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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2018-17-50-55</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2696</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЗДОРОВЫЙ РЕБЕНОК</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HEALTHY CHILD</subject></subj-group></article-categories><title-group><article-title>Вкусовые рецепторы – наши посредники в формировании вкусовых предпочтений ребенка</article-title><trans-title-group xml:lang="en"><trans-title>Taste receptors are our mediators in shaping the taste preferences of a child</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарова</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharova</surname><given-names>I. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Захарова Ирина Николаевна – доктор медицинских наук, профессор, заслуженный врач России, заведующая кафедрой педиатрии с курсом поликлинической педиатрии им. академика Г.Н. Сперанского ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» МЗ РФ, полный член EAACI, ESPGHAN</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Касьянова</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kasyanova</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Касьянова Анна Николаевна – клинический ординатор кафедры педиатрии с курсом поликлинической педиатрии им. академика Г.Н. Сперанского</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дмитриева</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dmitrieva</surname><given-names>Yu. А.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дмитриева Юлия Андреевна – кандидат медицинских наук, доцент кафедры педиатрии с курсом поликлинической педиатрии имени академика Г.Н. Сперанского</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мачнева</surname><given-names>Е. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Machneva</surname><given-names>Е. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мачнева Елена Борисовна – кандидат медицинских наук</p><p>Москва</p></bio><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuing Vocational Education of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российская детская клиническая больница, ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Children’s Clinical Hospital, Pirogov Russian National Research Medical University (RNRMU) of the Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>20</day><month>10</month><year>2018</year></pub-date><volume>0</volume><issue>17</issue><fpage>50</fpage><lpage>55</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Захарова И.Н., Касьянова А.Н., Дмитриева Ю.А., Мачнева Е.Б., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Захарова И.Н., Касьянова А.Н., Дмитриева Ю.А., Мачнева Е.Б.</copyright-holder><copyright-holder xml:lang="en">Zakharova I.N., Kasyanova A.N., Dmitrieva Y.А., Machneva Е.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2696">https://www.med-sovet.pro/jour/article/view/2696</self-uri><abstract><p>В статье представлены современные данные об основных молекулярных и генетических детерминантах формирования вкусовых предпочтений человека. Рассмотрена структура и механизм функционирования рецепторов сладкого вкуса, вкуса умами, кислого и горького вкусов, а также других молекул и клеточных структур, влияющих на восприятие вкусов, – белка густина, толлподобных рецепторов. Описана роль структур, обеспечивающих восприятие вкуса вне полости рта, – клеток гипоталамуса. Подчеркнуто значение генетического полиморфизма данных структур и важность взаимодействия генетических факторов и факторов внешней среды в формировании вкусовых предпочтений и пищевого поведения младенца. Особое внимание уделено практической значимости представленных данных в аспекте введения продуктов прикорма детям первого года жизни.</p></abstract><trans-abstract xml:lang="en"><p>The article presents modern data on the main molecular and genetic determinants of shaping the taste preferences. The authors present the structure and mechanism of the functioning of sweet taste receptors, umami taste, acidic and bitter tastes, as well as other molecules and cellular structures influencing the perception of flavors – the gust protein, toll-like receptors. They described the role of structures ensuring perception of taste outside the oral cavity – the cells of the hypothalamus. The article underlines the importance of the genetic polymorphism of these structures and the importance of interaction of genetic factors and environmental factors in shaping the taste preferences and eating behavior of the infant. Particular attention is given to the practical significance of the presented data in the context of introduction of supplemental foods for infants.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рецептор</kwd><kwd>ребенок</kwd><kwd>вкус</kwd><kwd>генетика</kwd><kwd>пища</kwd><kwd>рецепторы горького вкуса</kwd><kwd>рецепторы вкуса умами</kwd><kwd>рецепторы сладкого вкуса</kwd><kwd>вкусовые почки</kwd><kwd>ген белка густина</kwd><kwd>капсаицин</kwd><kwd>толл-подобные рецепторы (TLR)</kwd><kwd>танициты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>receptor</kwd><kwd>child</kwd><kwd>taste</kwd><kwd>genetics</kwd><kwd>food</kwd><kwd>bitter taste receptors</kwd><kwd>umami taste receptors</kwd><kwd>sweet taste receptors</kwd><kwd>taste buds</kwd><kwd>gust protein gene</kwd><kwd>capsaicin</kwd><kwd>toll-like receptors (TLR)</kwd><kwd>tanycytes</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kinnamon S.C. 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