<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2018-17-114-117</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2705</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БРОНХОПУЛЬМОНОЛОГИЯ И ЛОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BRONCHIAL PULMONOLOGY AND ENT</subject></subj-group></article-categories><title-group><article-title>Значение топической противовоспалительной терапии в лечении острых тонзиллофарингитов у детей</article-title><trans-title-group xml:lang="en"><trans-title>The role of topical anti-inflammatory therapy in the management of acute tonsillopharyngitis in children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кириченко</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kirichenko</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кириченко Ирина Михайловна – доктор медицинских наук, профессор кафедры оториноларингологии РУДН, заведующая отделением заболеваний носа и глотки ФГБУ НКЦО ФМБА</p><p>Москва </p></bio><bio xml:lang="en"><p>MD, Professor of the Department of Otorhinolaryngology, Russian Peoples’ Friendship University, Head of the Department of Nasal and Pharyngeal Diseases, Federal Research and Clinical Center of Otorhinolaryngology of FMBA Russia</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российского университета дружбы народов;&#13;
ФГБУ «Научно-клинический центр оториноларингологии» Федерального медико-биологического агентства России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Peoples’ Friendship University;&#13;
Federal Research and Clinical Center of Otorhinolaryngology of FMBA Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>20</day><month>10</month><year>2018</year></pub-date><volume>0</volume><issue>17</issue><fpage>114</fpage><lpage>117</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кириченко И.М., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Кириченко И.М.</copyright-holder><copyright-holder xml:lang="en">Kirichenko I.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2705">https://www.med-sovet.pro/jour/article/view/2705</self-uri><abstract><p>Острый тонзиллофарингит (ОТФ) – наиболее распространенное внебольничное инфекционное заболевание, в особенности среди детей. Основным проявлением ОТФ является боль в горле. Это самая частая причина обращения за амбулаторной медицинской помощью или самолечения. Повсеместное необоснованное применение антибиотиков при боли в горле как основной компонент в лечении ОТФ без учета наличия БГСА приводит к увеличению группы часто болеющих детей и дисбиозу слизистых. Топическая терапия боли в горле при лечении ОТФ наиболее эффективна и безопасна.</p></abstract><trans-abstract xml:lang="en"><p>Acute tonsillopharyngitis (ATP) is the most common community-acquired infection, especially in children. Sore throat is the main manifestation of ATP. This is the most common reason for seeking outpatient medical care or self-medication. The widespread, unreasonable use of antibiotics for the therapy of sore throat, as the main component in the treatment of ATP without taking into account the presence of group A beta-hemolytic streptococcus, leads to an increase in the number of frequently ill children and dysbiosis of the mucous membranes. Topical therapy of sore throat is the most effective and safe approach to the management of ATP.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>боль в горле</kwd><kwd>острый тонзиллофарингит</kwd><kwd>топическая терапия боли в горле</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sore throat</kwd><kwd>acute tonsillopharyngitis</kwd><kwd>topical therapy of sore throat</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Shulman ST, Bisno AL, Clegg HW, Gerber MA, Kaplan EL, Lee G, et al. Infectious Diseases Society of America. Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis, 2012, 55(10): e86-102.</mixed-citation><mixed-citation xml:lang="en">Shulman ST, Bisno AL, Clegg HW, Gerber MA, Kaplan EL, Lee G, et al. Infectious Diseases Society of America. Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America. Clin Infect Dis, 2012, 55(10): e86-102.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические рекомендации: острый тонзиллофарингит, КР306. Министерство здравоохранения Российской Федерации, Национальная медицинская ассоциация отоларингологов, 2016 г.</mixed-citation><mixed-citation xml:lang="en">Clinical guidelines for acute tonsillopharyngitis, CR306. Ministry of Health of the Russian Federation, National Medical Association of Otolaryngologists, 2016</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Острые респираторные заболевания у детей: лечение и профилактика. Научнопрактическая программа Союза педиатров России. М.: Международный Фонд охраны здоровья матери и ребенка, 2002. 69 с.</mixed-citation><mixed-citation xml:lang="en">Acute respiratory infections in children: treatment and prevention. Research and practical program of the Union of Pediatricians of Russia. M.: International Foundation for Maternal and Child Health, 2002. 69 p.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Белов Б.Н., Гришаева Т.П. Стрептококковый тонзиллит: современные аспекты антибактериальной терапии. Пед. фарм., 2007, 4(3): 58–66.</mixed-citation><mixed-citation xml:lang="en">Belov BN, Grishaeva TP. Streptococcal tonsillitis: modern aspects of antibiotic therapy. Ped Farm., 2007, 4 (3): 58–66.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">http: //mkb-10.com/index.php?pid = 9012.</mixed-citation><mixed-citation xml:lang="en">http: //mkb-10.com/index.php?pid = 9012.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">http: //mkb-10.com/index.php?pid = 9016</mixed-citation><mixed-citation xml:lang="en">http: //mkb-10.com/index.php?pid = 9016</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Самсыгина Г.А. Острый тонзиллофарингит у детей. Педиатрия, 2008, 3(8): 91-95.</mixed-citation><mixed-citation xml:lang="en">Самсыгина Г.А. Острый тонзиллофарингит у детей. Педиатрия, 2008, 3(8): 91-95. /Samsygin GA. Acute tonsillopharyngitis in children. Pediatriya, 2008, 3 (8): 91-95</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Bartlett JG. Management of respiratory tract infection. 3rd Ed. Philadelphia, 2001: 178–182.</mixed-citation><mixed-citation xml:lang="en">Bartlett JG. Management of respiratory tract infection. 3rd Ed. Philadelphia, 2001: 178–182.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Chiappini E, Regoli M, Bonsignori F, Sollai S, Parretti A, Galli L, de Martino M. Analysis of different recommendations from international guidelines for the management of acute pharyngitis in adults and children. Clin Ther, 2011, 33(1): 48-58.</mixed-citation><mixed-citation xml:lang="en">Chiappini E, Regoli M, Bonsignori F, Sollai S, Parretti A, Galli L, de Martino M. Analysis of different recommendations from international guidelines for the management of acute pharyngitis in adults and children. Clin Ther, 2011, 33(1): 48-58.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Pelucchi C, Grigoryan L, Galeone C, Esposito S, Huovinen P, Little P, et al. ESCMID Guideline for the management of acute sore throat. Clin Microbiol Infect, 2012, 18(Suppl 1): 1-28.</mixed-citation><mixed-citation xml:lang="en">Pelucchi C, Grigoryan L, Galeone C, Esposito S, Huovinen P, Little P, et al. ESCMID Guideline for the management of acute sore throat. Clin Microbiol Infect, 2012, 18(Suppl 1): 1-28.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Centor RM, Witherspoon JM, Dalton HP, et al. The diagnosis of strep throat in adults in the emergency room. Med Decis Making, 1981, 1(3): 239-46.</mixed-citation><mixed-citation xml:lang="en">Centor RM, Witherspoon JM, Dalton HP, et al. The diagnosis of strep throat in adults in the emergency room. Med Decis Making, 1981, 1(3): 239-46.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Гаращенко Т.Н., Богомильский М.Р., Радциг Е.Ю. Мукоактивные препараты в лечении острых и хронических заболеваний носа и околоносовых пазух, негнойных заболеваниях среднего уха у детей. Актуальные вопросы оториноларингологии детского возраста и фармакотерапии болезней ЛОР-органов. Юбилейный сборник научных трудов. М: 2001: 144-151.</mixed-citation><mixed-citation xml:lang="en">Garashchenko TN, Bogomilsky MR, Radtsig EYu. Mucoactive drugs in the treatment of acute and chronic diseases of the nose and paranasal sinuses, non-purulent diseases of the middle ear in children. Topical issues of children’s otorhinolaryngology and pharmacotherapy of diseases of ENT-organs. Jubilee collection of scientific papers. M: 2001: 144-151.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Учайкин В.Ф. Руководство по инфекционным заболеваниям у детей. М., 2002, 809 c.</mixed-citation><mixed-citation xml:lang="en">Учайкин В.Ф. Руководство по инфекционным заболеваниям у детей. М., 2002, 809 c. / Uchaykin VF. Guidelines for infectious diseases in children. M., 2002, 809 c.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Маянский А.Н., Маянский Н.А., Заславская М.И. Нуклеарный фактор-κB и воспаление. Цитокины и воспаление, 2007, 6(2): 3-9.</mixed-citation><mixed-citation xml:lang="en">Mayansky AN, Mayansky NA, Zaslavskaya MI. Nuclear factor-κB and inflammation. Tsitokiny i Vospalenie, 2007, 6 (2): 3-9.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Савлевич Е.Л., Дорощенко Н.Э. Патогенетическое обоснование топической терапии воспалительной патологии ротоглотки. Фарматека, 2015, 1: 76-79.</mixed-citation><mixed-citation xml:lang="en">Savlevich EL, Doroschenko NE. Pathogenetic justification of topical treatment of inflammatory pathology of the oropharynx. Pharmateca, 2015, 1: 76-79.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Савлевич Е.Л., Дорощенко Н.Э., Славинская И.С., Фариков С.Э. Важные нюансы воспалительного процесса в ротоглотке и выбор тактики оптимального лечения. Медицинский совет, 2017, 16: 48-52.</mixed-citation><mixed-citation xml:lang="en">Savlevich EL, Doroschenko NE, Slavinskaya IS, Farikov SE. Important nuances of the inflammatory process in the oropharynx and the choice of optimal treatment tactics. Meditsinsky Sovet, 2017, 16: 48-52</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
