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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2018-19-122-125</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2759</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original studies</subject></subj-group></article-categories><title-group><article-title>Общая выживаемость при олигометастатическом поражении у пациентов с немелкоклеточным раком легкого в группе комбинированного лечения</article-title><trans-title-group xml:lang="en"><trans-title>Intermediate results of combination therapy in patients with oligometastatic non-small cell lung cancer</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юдин</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Yudin</surname><given-names>D. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., старший научный сотрудник</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лактионов</surname><given-names>К. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Laktionov</surname><given-names>K. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, зав. отд.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маринов</surname><given-names>Д. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Marinov</surname><given-names>D. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., ведущий научный сотрудник</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бредер</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Breder</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., ведущий научный сотрудник</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аллахвердиев</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Allakhverdiev</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., ведущий научный сотрудник</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борисова</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Borisova</surname><given-names>T. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., старший научный сотрудник</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бекяшев</surname><given-names>А. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Bekyashev</surname><given-names>A. H.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, зав. отд.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лактионов</surname><given-names>К. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Laktionov</surname><given-names>K. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, ведущий научный сотрудник</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алешин</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Aleshin</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., с.н.с.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ардзинба</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ardzinba</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., врач-хирург</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Blokhin National Medical Research Cancer Centre, Federal State Budgetary Institution of the Ministry of Health of Russia, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>11</day><month>11</month><year>2018</year></pub-date><volume>0</volume><issue>19</issue><fpage>122</fpage><lpage>125</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Юдин Д.И., Лактионов К.К., Маринов Д.Т., Бредер В.В., Аллахвердиев А.К., Борисова Т.Н., Бекяшев А.Х., Лактионов К.П., Алешин В.А., Ардзинба М.С., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Юдин Д.И., Лактионов К.К., Маринов Д.Т., Бредер В.В., Аллахвердиев А.К., Борисова Т.Н., Бекяшев А.Х., Лактионов К.П., Алешин В.А., Ардзинба М.С.</copyright-holder><copyright-holder xml:lang="en">Yudin D.I., Laktionov K.K., Marinov D.T., Breder V.V., Allakhverdiev A.K., Borisova T.N., Bekyashev A.H., Laktionov K.P., Aleshin V.A., Ardzinba M.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2759">https://www.med-sovet.pro/jour/article/view/2759</self-uri><abstract><p>Среди больных метастатическим раком легкого в настоящее время выделяют небольшую группу с олигометастатическим поражением (наличием наряду с первичной опухолью легкого солитарного метастатического очага в другом органе). В приведенном в данной статье исследовании 14 больным было проведено комплексное лечение олигометастатического немелкоклеточного рака легкого (оНМРЛ), включавшее системную терапию и локальное воздействие на солитарный метастаз. Медиана общей выживаемости для этой группы составила 20 месяцев (16,0–32,6, ДИ 95%). 1-годичная и 2-годичная общая выживаемость составили 84,5 и 65,7% соответственно. Полученные результаты демонстрируют возможности агрессивного подхода к лечению больных оНМРЛ.</p></abstract><trans-abstract xml:lang="en"><p>At the present time, a small group of patients with oligometastases (who have a solitary metastatic lesion in another organ along with the primary tumour of the lung) is differentiated among the patients with metastatic lung cancer. A total of 14 patients of the study citied in this article underwent a comprehensive treatment of oligometastatic non-small cell lung cancer (ONSCLC), which included systemic therapy and local influence on solitary metastasis. The median overall survival for this group was 20 months (16.0–32.6, CI 95%). The 1-year and 2-year overall survival rates accounted for 84.5 and 65.7%, respectively. The findings of the study demonstrate the possibilities of an aggressive approach to the treatment of patients with ONLDLC.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>НМРЛ</kwd><kwd>олигометастатическое поражение</kwd><kwd>рак легкого</kwd></kwd-group><kwd-group xml:lang="en"><kwd>NSCLC</kwd><kwd>oligometastatic disease</kwd><kwd>lung cancer</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Каприн А.Д., Старинский В.В., Петрова Г.В. Состояние онкологической помощи населению России в 2015 году. М., 2016.</mixed-citation><mixed-citation xml:lang="en">Kaprin AD, Starinsky VV, Petrova GV. The state of cancer care in Russia, 2015. 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