medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2018-20-112-115medsovet-2784Research ArticleШкола оториноларингологаSchool otorhinolaryngologyНеинфекционные причины хронического фарингитаNon-infectious causes of chronic pharyngitisКосяковС. Я.KosyakovS. Ya.

д.м.н., профессор, заведующий кафедрой оториноларингологии

АнготоеваИ. Б.AngotoevaI. B.

к.м.н., доцент кафедры оториноларингологии

ИсамовА. Н.IsamovA. N.

ординатор кафедры оториноларингологии

ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России, МоскваРоссияRussian Medical Academy of Continuing Postgraduate Education of the Ministry of Health of Russia, MoscowRussian Federation201814112018020112115Copyright © Косяков С.Я., Анготоева И.Б., Исамов А.Н., 20182018Косяков С.Я., Анготоева И.Б., Исамов А.Н.Kosyakov S.Y., Angotoeva I.B., Isamov A.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/2784

Хронический фарингит (ХФ) – это часто встречающееся заболевание, не связанное с инфекциями и не требующее назначения системной антибиотикотерапии. К развитию ХФ приводит множество неинфекционных причин. Несмотря на их разнообразие и вариабельность, в основе патогенеза ХФ лежит воспалительный процесс слизистой оболочки ротоглотки. Основным симптомом этого процесса является боль в горле, которую с успехом могут купировать препараты местного действия.

Chronic pharyngitis (CP) is a common disease that is not associated with infections and does not require administration of any systemic antibiotic therapy. Many non-infectious factors cause CP. Despite diversity and variability of factors, the inflammatory process of the pharyngeal mucosa lie at the root of the pathogenesis of CP. A sore throat is the main symptom of this process, which can be successfully relieved with local drugs.

хронический фарингитболь в горлебензидаминchronic pharyngitissore throatbenzydamineReferencesEbell MN, Smith MA, Barry HC, Ives K, Carey M. The rational ckinical examination. Does this patient have strep throat? JAMA, 2000, 284(22): 2912-2918.Ebell MN, Smith MA, Barry HC, Ives K, Carey M. The rational ckinical examination. Does this patient have strep throat? JAMA, 2000, 284(22): 2912-2918.Пальчун В.Т., Магомедов М.М., Лучихин Л.А. Оториноларингология: учебник для вузов. 2-е изд., испр. и доп. 2008. 656 с.Palchun VT, Magomedov MM, Luchikhin LA. Otolaryngology: a textbook for higher educational institutions. 2nd revised and enlarged edition. 2008. 656 p.Лопатин А.С. Лечение острого и хронического фарингита. РМЖ, 2001, 16: 694.Lopatin AS. Treatment of acute and chronic pharyngitis. RMJ, 2001, 16: 694.Носуля Е.В. Диагностика и лечение заболеваний глотки: Учеб. пособие. М: Аванпорт, 2014. С. 19.Nosulya EV. Diagnosis and treatment of diseases of the pharynx: a study guide. M: Avanport, 2014. P. 19.Renner B, Mueller CA, Shepard A. Environmental and non-infectious factors in the aetiology of pharyngitis (sore throat). Inflamm Res, 2012, 61(10): 1041-1052.Renner B, Mueller CA, Shepard A. Environmental and non-infectious factors in the aetiology of pharyngitis (sore throat). Inflamm Res, 2012, 61(10): 1041-1052.Barry DW, Vaezi MF. Laryngopharyngeal reflux: more questions than answers. Cleve Clin J Med, 2010, 77(5): 327-334.Barry DW, Vaezi MF. Laryngopharyngeal reflux: more questions than answers. Cleve Clin J Med, 2010, 77(5): 327-334.Asahi S, Uehara R, Watanabe M, Tajimi M, Oki I, Ojima T et al. Respiratory symptoms correlating to smoking prevalence: the national nutrition survey and the national life-style survey in Japan. J Epidemiol, 2003, 13(4): 226-231.Asahi S, Uehara R, Watanabe M, Tajimi M, Oki I, Ojima T et al. Respiratory symptoms correlating to smoking prevalence: the national nutrition survey and the national life-style survey in Japan. J Epidemiol, 2003, 13(4): 226-231.Wakefield M, Cameron M, Inglis G, Letcher T, Durkin S. Second hand smoke exposure and respiratory symptoms among casino, club, and office workers in Victoria, Australia. J Occup Environ Med, 2005, 47(7): 698-703.Wakefield M, Cameron M, Inglis G, Letcher T, Durkin S. Second hand smoke exposure and respiratory symptoms among casino, club, and office workers in Victoria, Australia. J Occup Environ Med, 2005, 47(7): 698-703.Renner B, Meindorfner F, Kaegler M, Thurauf N, Barocka A, Kobal G. Discrimination of R and S-nicotine by the trigeminal nerve. Chem Senses, 1998, 23: 602.Renner B, Meindorfner F, Kaegler M, Thurauf N, Barocka A, Kobal G. Discrimination of R and S-nicotine by the trigeminal nerve. Chem Senses, 1998, 23: 602.Griesel AG, Germishuys PJ. Salivary immunoglobulin A levels of persons who have stopped smoking. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 1999, 87(2): 170-173.Griesel AG, Germishuys PJ. Salivary immunoglobulin A levels of persons who have stopped smoking. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 1999, 87(2): 170-173.Verones B, Oortgiesen M. Neurogenic inflammation and particulate matter (PM) air pollutants. Neurotoxicology, 2001, 22(6): 795-810.Verones B, Oortgiesen M. Neurogenic inflammation and particulate matter (PM) air pollutants. Neurotoxicology, 2001, 22(6): 795-810.Perez-Padilla R, Schilmann A, Riojas-Rodriguez H. Respiratory health effects of indoor air pollution. Int J Tuberc Lung Dis, 2010, 14(9): 1079-1086.Perez-Padilla R, Schilmann A, Riojas-Rodriguez H. Respiratory health effects of indoor air pollution. Int J Tuberc Lung Dis, 2010, 14(9): 1079-1086.Peters J, Hedley AJ, Wong CM, Lam TH, Ong SG, Liu J et al. Effects of an ambient air pollution intervention and environmental tobacco smoke on children’s respiratory health in Hong Kong. Int J Epidemiol, 1996, 25(4): 821-828.Peters J, Hedley AJ, Wong CM, Lam TH, Ong SG, Liu J et al. Effects of an ambient air pollution intervention and environmental tobacco smoke on children’s respiratory health in Hong Kong. Int J Epidemiol, 1996, 25(4): 821-828.Webber MP, Gustave J, Lee R, Niles JK, Kelly K, Cohen HW et al. Trends in respiratory symptoms of fire fighters exposed to the world trade center disaster: 2001–2005. Environ Health Perspect, 2009, 117(6): 975-980.Webber MP, Gustave J, Lee R, Niles JK, Kelly K, Cohen HW et al. Trends in respiratory symptoms of fire fighters exposed to the world trade center disaster: 2001–2005. Environ Health Perspect, 2009, 117(6): 975-980.Reinikainen LM, Jaakkola JJ. Effects of temperature and humidification in the office environment. Arch Environ Health, 2001, 56(4): 365-368.Reinikainen LM, Jaakkola JJ. Effects of temperature and humidification in the office environment. Arch Environ Health, 2001, 56(4): 365-368.Mäkinen TM, Juvonen R, Jokelainen J, Harju TH, Peitso A, Bloigu A et al.. Cold temperature and low humidity are associated with increased occurrence of respiratory tract infections. Respir Med, 2009, 103(3): 456-462.Mäkinen TM, Juvonen R, Jokelainen J, Harju TH, Peitso A, Bloigu A et al.. Cold temperature and low humidity are associated with increased occurrence of respiratory tract infections. Respir Med, 2009, 103(3): 456-462.Lyons RA, Temple JM, Evans D, Fone DL, Palmer SR. Acute health effects of the Sea Empress oil spill. J Epidemiol Community Health, 1999, 53(5): 306-310.Lyons RA, Temple JM, Evans D, Fone DL, Palmer SR. Acute health effects of the Sea Empress oil spill. J Epidemiol Community Health, 1999, 53(5): 306-310.Bener A, Lestringant GG, Beshwari MM, Pasha MA. Respiratory symptoms, skin disorders and serum IgE levels in farm workers. Allerg Immunol (Paris), 1999, 31(2): 52-56.Bener A, Lestringant GG, Beshwari MM, Pasha MA. Respiratory symptoms, skin disorders and serum IgE levels in farm workers. Allerg Immunol (Paris), 1999, 31(2): 52-56.Woodin MA, Hauser R, Liu Y, Smith TJ, Siegel PD, Lewis DM et al. Molecular markers of acute upper airway inflammation in workers exposed to fuel-oil ash. Am J Respir Crit Care Med, 1998, 158(1): 182-187.Woodin MA, Hauser R, Liu Y, Smith TJ, Siegel PD, Lewis DM et al. Molecular markers of acute upper airway inflammation in workers exposed to fuel-oil ash. Am J Respir Crit Care Med, 1998, 158(1): 182-187.Riboldi E, Frascaroli G, Transidico P, Luini W, Bernasconi S, Mancini F et al.. Benzydamine inhibits monocyte migration and MAPK activation induced by chemotactic agonists. Br J Pharmacol, 2003 Sep, 140(2): 377-383.Riboldi E, Frascaroli G, Transidico P, Luini W, Bernasconi S, Mancini F et al.. Benzydamine inhibits monocyte migration and MAPK activation induced by chemotactic agonists. Br J Pharmacol, 2003 Sep, 140(2): 377-383.Quane PA, Graham GG, Ziegler JB. Pharmacology of benzydamine. Inflammopharmacology, 1998, 6(2): 95-107.Quane PA, Graham GG, Ziegler JB. Pharmacology of benzydamine. Inflammopharmacology, 1998, 6(2): 95-107.Pina-Vaz C, Rodrigues AG, Sansonetty F, Martinez-De-Oliveira J, Fonseca AF, Mårdh PA. Antifungal activity of local anesthetics against Candida species. Infect Dis Obstet Gynecol, 2000, 8(3-4): 124-137.Pina-Vaz C, Rodrigues AG, Sansonetty F, Martinez-De-Oliveira J, Fonseca AF, Mårdh PA. Antifungal activity of local anesthetics against Candida species. Infect Dis Obstet Gynecol, 2000, 8(3-4): 124-137.Limb M et al. Scintigraphy can be used to compare delivery of sore throat formulations. Int J Clin Pract, 2009 Apr, 63(4): 606-612.Limb M et al. Scintigraphy can be used to compare delivery of sore throat formulations. Int J Clin Pract, 2009 Apr, 63(4): 606-612.Савлевич Е.Л., Дорошенко Н.Э., Славинская И.С., Фариков С.Э. Важные нюансы воспалительного процесса в ротоглотке и выбор тактики оптимального лечения. Медицинский Совет, 2017, 16: 48-54Savlevich EL, Doroshenko NE, Slavinskaya IS, Farikov SE./ Important nuances of the inflammatory process in the oropharynx and the choice of optimal management of the disease. Meditsinsky Sovet, 2017, 16: 48-54.

The authors declare that there are no conflicts of interest present.