medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2018-18-10-15medsovet-2787Research ArticleКОГНИТИВНЫЕ НАРУШЕНИЯ И ДЕМЕНЦИЯCOGNITIVE IMPAIRMENT AND DEMENTIAПостинсультные когнитивные нарушенияCognitive impairment and dementiaПарфеновВ. А.ParfenovV. A.

Парфенов Владимир Анатольевич – доктор медицинских наук, профессор, заведующий кафедрой нервных болезней и нейрохирургии ПМГМУ им. И.М. Сеченова; директор Клиники нервных болезней им. А. Я. Кожевникова ПМГМУ им. И.М. Сеченова

ВербицкаяС. В.VerbitskayaS. V.

Вербицкая Светлана Викторовна – кандидат медицинских наук, докторант кафедры нервных и нейрохирургии

ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский университет)РоссияSechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University)Russian Federation2018161120180181015Copyright © Парфенов В.А., Вербицкая С.В., 20182018Парфенов В.А., Вербицкая С.В.Parfenov V.A., Verbitskaya S.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/2787

Когнитивные нарушения (КН) представляют одну из причин инвалидности больных, перенесших инсульт. Анализируются распространенность, механизмы развития, проявления, диагноз, лечение и профилактика постинсультных КН. Отмечается, что КН у больного, перенесшего инсульт, могут быть вызваны не только очаговым сосудистым поражением головного мозга, но  и наличием сопутствующих сосудистых и дегенеративных поражений. Представлены результаты собственного изучения в течение 5 лет КН у 350 больных, перенесших инсульт. Лечение и профилактика прогрессирования КН основаны на профилактике инсульта, нелекарственных и лекарственных методах улучшения когнитивных функций. Обсуждаются данные по использованию Церебролизина при инсульте, результаты двух последних метаанализов применения Церебролизина.

Cognitive impairment (CI) is one of the causes of acquired disability in post-stroke patients. The article presents an analysis of the prevalence, pathogenesis, manifestations, diagnosis, treatment and prevention of post-stroke CI. It is noted that CI can be caused not only by focal vascular brain damage, but also by the presence of concomitant vascular and degenerative lesions in stroke patients. The authors present the results of their own study of CI in 350 patients after stroke within 5 years. The treatment and prevention of CI progression are based on stroke prevention, non-pharmaceutical and pharmaceutical methods for improving cognitive functions. The article discusses data on the use of Cerebrolysin in post-stroke patients, the results of the two latter meta-analyses of Cerebrolysin use.

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The authors declare that there are no conflicts of interest present.