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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2019-1-19-23</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2893</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОГНИТИВНЫЕ НАРУШЕНИЯ И ДЕМЕНЦИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COGNITIVE IMPAIRMENT AND DEMENTIA</subject></subj-group></article-categories><title-group><article-title>Безопасность терапии EGb 761® у коморбидных пациентов</article-title><trans-title-group xml:lang="en"><trans-title>Safety of EGb 761® therapy in comorbid patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пизова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pizova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, кафедра нервных болезней с медицинской генетикой и нейрохирургией Федерального государственного бюджетного образовательного учреждения высшего образования «Ярославский государственный медицинский университет» Министерства здравоохранения Российской Федерации</p></bio><bio xml:lang="en"><p>Dr. of Sci. (Med), Professor, Department of Nervous Diseases with Medical Genetics and Neurosurgery of the Federal State Budgetary Educational Institution of Higher Education «Yaroslavl State Medical University» of the Ministry of Health of the Russian Federation</p></bio><email xlink:type="simple">pizova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное образовательное учреждение высшего образования «Ярославский государственный медицинский университет» Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Educational Institution of Higher Education «Yaroslavl State Medical University» of the Ministry of Health of the&#13;
Russian Federation<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>05</day><month>03</month><year>2019</year></pub-date><volume>0</volume><issue>1</issue><fpage>19</fpage><lpage>23</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Пизова Н.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Пизова Н.В.</copyright-holder><copyright-holder xml:lang="en">Pizova N.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2893">https://www.med-sovet.pro/jour/article/view/2893</self-uri><abstract><p>В статье представлены данные различных исследований о частоте хронических заболеваний и состояний среди взрослых, что является серьезной проблемой общественного здравоохранения сегодня. Освещена проблема коморбидности в условиях демографического старения населения. Представлены результаты недавно проведенных исследований по частоте развития побочных явлений в зависимости от количества принимаемых лекарственных препаратов. Показано, что в пожилом возрасте еще одной проблемой становится развитие когнитивных нарушений. Описаны результаты выявляемости когнитивных нарушений среди пациентов стационаров общего профиля. Представлены данные об эффективности применения препарата из стандартизованного экстракта листьев гинкго билоба EGb 761® для профилактики и лечения когнитивных расстройств. Рассмотрен вопрос воздействия препарата EGb 761® у коморбидных пациентов, принимающих антиагреганты и антикоагулянты, на коагуляционные свойства крови.</p><sec><title> </title><p> </p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><p>The article presents data from various studies on the incidence of chronic diseases and conditions among adults, which is a serious public health problem today. The problem of comorbidity in the conditions of demographic aging of the population is highlighted. The results of recent studies on the frequency of side effects depending on the number of drugs taken are presented. It is shown that in old age another problem is the development of cognitive impairment. The results of detection of cognitive disorders among patients of general hospitals are described. Data on the efficacy of the drug application from the standardized extract of ginkgo biloba leaves EGb 761® for prophylaxis and treatment of cognitive disorders are presented. The question of the effect of EGb 761® preparation on blood coagulation properties in comorbid patients taking antiagregants and anticoagulants was considered.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>коморбидность</kwd><kwd>когнитивные нарушения</kwd><kwd>стандартизованный экстракт листьев гинкго билоба EGb 761®</kwd><kwd>Мемоплант</kwd></kwd-group><kwd-group xml:lang="en"><kwd>comorbidity</kwd><kwd>cognitive disorders</kwd><kwd>standardized extract of ginkgo biloba leaves EGb 761®</kwd><kwd>Memoplant</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">European Commission. Active ageing. [cited 2015 Jul 28]. 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