<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2019-8-60-65</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-2953</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКТУАЛЬНОЕ В ОТОРИНОЛАРИНГОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ACTUAL IN OTORHINOLARYNGOLOGY</subject></subj-group></article-categories><title-group><article-title>Применение назальных деконгестантов для коррекции дыхательной и обонятельной функции носа</article-title><trans-title-group xml:lang="en"><trans-title>The use of nasal decongestants to correction the respiratory and olfactory function of the nose</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Morozova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор кафедры болезней уха, горла и носа Федерального государственного автономного образовательного учреждения высшего образования «Первый Московский государственный медицинский университет имени И.М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский университет)</p></bio><bio xml:lang="en"><p>Dr. of Sci. (Med.), Professor of Chair for Ear, Nose and Throat Diseases, Federal State Autonomous Educational Institution of Higher Education «Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University)</p></bio><email xlink:type="simple">doctormorozova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Топоркова</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Toporkova</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант кафедры болезней уха, горла и носа Федерального государственного автономного образовательного учреждения высшего образования «Первый Московский государственный медицинский университет имени И.М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский университет)</p></bio><bio xml:lang="en"><p>a postgraduate student of Chair for Ear, Nose and Throat Diseases, Federal State Autonomous Educational Institution of Higher Education «Sechenov First Moscow State Medical University» of the Ministry of Heath of the Russian Federation (Sechenov University)</p></bio><email xlink:type="simple">linatoporkova94@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное автономное образовательное учреждение высшего образования «Первый Московский государственный&#13;
медицинский университет имени И.М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of&#13;
the Ministry of Health of the Russian Federation (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>18</day><month>04</month><year>2019</year></pub-date><volume>0</volume><issue>8</issue><fpage>60</fpage><lpage>65</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Морозова С.В., Топоркова Л.А., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Морозова С.В., Топоркова Л.А.</copyright-holder><copyright-holder xml:lang="en">Morozova S.V., Toporkova L.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/2953">https://www.med-sovet.pro/jour/article/view/2953</self-uri><abstract><p>Одними из основных функций носа является дыхательная и обонятельная. Затруднение носового дыхания, заложенность носа, выделения из носа могут затруднять дыхательную и обонятельную функции носа или делать их невозможными. Чаще всего причиной становится отек слизистой оболочки. Назальная обструкция и ринорея – наиболее часто встречающиеся симптомы при заболеваниях полости носа и околоносовых пазух. Большое значение имеет применение местных сосудосуживающих средств для устранения отека в полости носа и профилактики осложнений, связанных с дисфункцией слуховой трубы. Доказано, что применение назальных деконгестантов способствует уменьшению отека в полости носа и в области остеомеатального комплекса. Отривин Увлажняющая формула, Отривин Ментол, Отривин Комплекс являются эффективными и хорошо переносимыми средствами для устранения отека в полости носа и уменьшения выделений из носа, а следовательно, восстановления обонятельной функции.</p></abstract><trans-abstract xml:lang="en"><p>One of the main functions of the nose is respiratory and olfactory. Difficulty in nasal breathing, nasal congestion, nasal discharge can complicate the respiratory and olfactory functions of the nose or make them impossible. Most often the cause is swelling of the mucous. Nasal obstruction and rhinorrhea are the most common symptoms in diseases of the nasal cavity and paranasal sinuses. Of great importance is the use of local vasoconstrictors to eliminate swelling in the nasal cavity and prevent complications associated with auditory tube dysfunction. It is proved that the use of nasal decongestants helps to reduce swelling in the nasal cavity and in the osteomeatal complex. Otrivin Moisturizing formula, Otrivin Menthol, Otrivin Complex and Otrivin Sea are effective and well tolerated means to eliminate swelling in the nasal cavity and reduce nasal discharge and rehabilitation of olfactory function.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>назальная обструкция</kwd><kwd>ринорея</kwd><kwd>обоняние</kwd><kwd>назальные деконгестанты</kwd><kwd>ирригационная терапия</kwd><kwd>ксилометазолин</kwd><kwd>Отривин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>nasal obstruction</kwd><kwd>rhinorrhea</kwd><kwd>sense of smell</kwd><kwd>nasal degongestants</kwd><kwd>irrigation therapy</kwd><kwd>xylometazoline</kwd><kwd>otrivin</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Пискунов Г.З. Физиология и патофизиология носа и околоносовых пазух. Российская ринология. 2017;25(3):51-57. doi: 10.17116/ rosrino201725351-57. [Piskunov G.Z. Physiology and pathophysiology of the nose and paranasal sinuses. Rossijskaja rinologiya. 2017;25(3):51-57. doi: 10.17116/rosrino201725351-57.] (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Piskunov G.Z. Physiology and pathophysiology of the nose and paranasal sinuses. Rossijskaja rinologiya. 2017;25(3):51-57. doi: 10.17116/rosrino201725351-57.] (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Hummel T. et. al. EPOS. Supplement 26 Olfactory dysfunctions. 2017, p. 6.</mixed-citation><mixed-citation xml:lang="en">Hummel T. et. al. EPOS. Supplement 26 Olfactory dysfunctions. 2017, p. 6.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">European Position Paper on Rhinosinusitis and Nasal Polyps 2012. Rhinology supplement. 2012;23:1-298,</mixed-citation><mixed-citation xml:lang="en">European Position Paper on Rhinosinusitis and Nasal Polyps 2012. Rhinology supplement. 2012;23:1-298,</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Острый синусит. Клинические рекомендации. Национальная медицинская ассоциация оториноларингологов. 2016:3-25. [Acute sinusitis. Clinical guidelines. National medical Association of otolaryngologists. 2016:3-25.] (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Acute sinusitis. Clinical guidelines. National medical Association of otolaryngologists. 2016:3-25.] (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Свистушкин В.М., Славский А.Н., Пшонкина Д.М. Бактериофаги в комплексном лечении острого бактериального риносинусита. РМЖ.. 2014;26:19-25. [Svistushkin V.M., Slavsky A.N., Pshonkina D.M. Bacteriophages in the complex treatment of acute bacterial rhinosinusitis. RMG. 2014;26:19-25.] (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Svistushkin V.M., Slavsky A.N., Pshonkina D.M. Bacteriophages in the complex treatment of acute bacterial rhinosinusitis. RMG. 2014;26:19-25.] (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Onerci T.M. Diagnosis in otorhinolaryngology, Springer-Verlag Berlin Heidelberg. 2009: 60-65.</mixed-citation><mixed-citation xml:lang="en">Onerci T.M. Diagnosis in otorhinolaryngology, Springer-Verlag Berlin Heidelberg. 2009: 60-65.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Дюннебир Э.А. Лучевая диагностика. Оториноларингология. Медпресс-информ, 2013:202-213. [Dunnebier E.A. Radiodiagnostics. Otorhinolaryngology. Medpress-inform, 2013:202-213.] (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Dunnebier E.A. Radiodiagnostics. Otorhinolaryngology. Medpress-inform, 2013:202-213.] (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Свистушкин В.М., Топоркова Л.А. Национальные рекомендации по лечению больных острыми респираторными инфекциями верхних отделов дыхательных путей: что важно знать терапевту? Фарматека. 2017:2-17. [Svistushkin V.M., Toporkova L.A. National guidelines for the treatment of patients with acute respiratory infections of the upper respiratory tract: what is important to know the therapist? Pharmateca. 2017:2-17.] (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Svistushkin V.M., Toporkova L.A. National guidelines for the treatment of patients with acute respiratory infections of the upper respiratory tract: what is important to know the therapist? Pharmateca. 2017:2-17.] (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Фармакотерапия гнойно-воспалительной патологии ЛОР-органов. Под ред. А. И. Крюкова. М., 2018:1-30. [Pharmacotherapy of purulent inflammatory pathology of ENT organs. Under the editorship of A.I. Kryukov. Moscow, 2018:1-30.] (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Pharmacotherapy of purulent inflammatory pathology of ENT organs. Under the editorship of A.I. Kryukov. Moscow, 2018:1-30.] (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Sahin G. Nitric oxide: a promising methodological approach in airway diseases. Int Arch Allergy Immunol. 2011;156(4):352-61</mixed-citation><mixed-citation xml:lang="en">Sahin G. Nitric oxide: a promising methodological approach in airway diseases. Int Arch Allergy Immunol. 2011;156(4):352-61</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Пальчун В.Т. Оториноларингология. Национальное руководство. М.: ГЭОТАР-медиа, 2009:626-762. [Palchun V.T. Otorhinolaryngology. National leadership. M.: GEOTAR-media. 2009:626-762.] (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Palchun V.T. Otorhinolaryngology. National leadership. M.: GEOTAR-media. 2009:626-762.] (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Морозова С.В. Профилактика осложнений острого инфекционного ринита у детей. РМЖ. 2014;3:198-202. [Morozova S.V. Prevention of complications of acute infectious rhinitis in children. RMG. 2014;3:198-202.] (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Morozova S.V. Prevention of complications of acute infectious rhinitis in children. RMG. 2014;3:198-202.] (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Stringer S.P., Mancuso A.A., Avino A.J. Effect of a topical vasoconstrictor on computed tomography of paranasal sinus disease. The Laryngoscope. 1993;103(1 Pt 1):6-9</mixed-citation><mixed-citation xml:lang="en">Stringer S.P., Mancuso A.A., Avino A.J. Effect of a topical vasoconstrictor on computed tomography of paranasal sinus disease. The Laryngoscope. 1993;103(1 Pt 1):6-9</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Benammar-Englmaier M., Hallermeier J.K., Englmaier B. Alphamimetic effects on nasal mucosa in magnetic resonance tomography. Digitale Bild Diagn. 1990;10(2):46-50</mixed-citation><mixed-citation xml:lang="en">Benammar-Englmaier M., Hallermeier J.K., Englmaier B. Alphamimetic effects on nasal mucosa in magnetic resonance tomography. Digitale Bild Diagn. 1990;10(2):46-50</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Westerveld G.J., Voss H.P., van der Hee R.M., de Haan-Koelewijn G.J., den Hartog G.J., Scheeren R.A., et al. Inhibition of nitric oxide synthase by nasal decongestants. The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology. 2000;16(3):437-44</mixed-citation><mixed-citation xml:lang="en">Westerveld G.J., Voss H.P., van der Hee R.M., de Haan-Koelewijn G.J., den Hartog G.J., Scheeren R.A., et al. Inhibition of nitric oxide synthase by nasal decongestants. The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology. 2000;16(3):437-44</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Wester veld G.J., Scheeren R.A., Dekker I., Griffioen D.H., Voss H.P., Bast A. Anti-oxidant actions of oxymethazoline and xylomethazoline. Eur J Pharmacol. 1995;291(1):27-31</mixed-citation><mixed-citation xml:lang="en">Wester veld G.J., Scheeren R.A., Dekker I., Griffioen D.H., Voss H.P., Bast A. Anti-oxidant actions of oxymethazoline and xylomethazoline. Eur J Pharmacol. 1995;291(1):27-31</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Pneumatikos I., Konstantonis D., Dragoumanis C., Danielides V., Bouros D. Preventing nosocomial sinusitis in the ICU: Reply to van Zanten et al. Intensive Care Medicine. 2006;32(9):1452-3.</mixed-citation><mixed-citation xml:lang="en">Pneumatikos I., Konstantonis D., Dragoumanis C., Danielides V., Bouros D. Preventing nosocomial sinusitis in the ICU: Reply to van Zanten et al. Intensive Care Medicine. 2006;32(9):1452-3.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Инструкция по применению медицинского препарата Отривин Увлажняющая формула. http://www.otrivin.ru/products/otrivinuvlazhnyayuschaya-formula-instruktsiya.html. Ссылка активна на 15.03.19. [Instructions for use of the medical drug Otrivin Moisturizing formula. http://www.otrivin.ru/products/otrivinuvlazhnyayuschaya-formula-instruktsiya.html. Accessed 15.03.19.] (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Instructions for use of the medical drug Otrivin Moisturizing formula. http://www.otrivin.ru/products/otrivinuvlazhnyayuschaya-formula-instruktsiya.html. Accessed 15.03.19.] (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Eccles R. et al. The nasal decongestant effect of xylometazoline in the common cold. American Journal of Rhinology. 2008 September-October;22(5):495</mixed-citation><mixed-citation xml:lang="en">Eccles R. et al. The nasal decongestant effect of xylometazoline in the common cold. American Journal of Rhinology. 2008 September-October;22(5):495</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Инструкция по применению препарата Отривин Комплекс. http://www.otrivin.ru/ products/otrivin-uvlazhnyayuschaya-formulainstruktsiya.html. Ссылка активна на 15.03.19. [Instructions for use of the drug Otrivin Complex. http://www.otrivin.ru/products/otrivin-uvlazhnyayuschaya-formula-instruktsiya. html. Accessed 15.03.19.] (In Russ.)</mixed-citation><mixed-citation xml:lang="en">Instructions for use of the drug Otrivin Complex. http://www.otrivin.ru/products/otrivin-uvlazhnyayuschaya-formula-instruktsiya. html. Accessed 15.03.19.] (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Eccles R., Martensson K. &amp; Chen Sh.C. Effects of intranasal xylometazoline, alone or in combination with ipratropium, in patients with common cold. Current Medical Research and Opinion. 2010; 26(4):889-899. Doi: 10.1185/03007991003648015.</mixed-citation><mixed-citation xml:lang="en">Eccles R., Martensson K. &amp; Chen Sh.C. Effects of intranasal xylometazoline, alone or in combination with ipratropium, in patients with common cold. Current Medical Research and Opinion. 2010; 26(4):889-899. Doi: 10.1185/03007991003648015.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Hayden F.G., Diamond L., Wood P.B., Korts D.C., Wecker M.T. Effectiveness and Safety of Intranasal Ipratropium Bromide in Common Colds: A Randomized, Double-Blind, Placebo-Controlled Trial. Ann Intern Med.1996;125:89–97. doi: 10.7326/0003-4819-125-2-199607150-00002.</mixed-citation><mixed-citation xml:lang="en">Hayden F.G., Diamond L., Wood P.B., Korts D.C., Wecker M.T. Effectiveness and Safety of Intranasal Ipratropium Bromide in Common Colds: A Randomized, Double-Blind, Placebo-Controlled Trial. Ann Intern Med.1996;125:89–97. doi: 10.7326/0003-4819-125-2-199607150-00002.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
