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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2015-11-80-83</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-296</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИНЕКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GYNECOLOGY</subject></subj-group></article-categories><title-group><article-title>Бактериальный вагиноз: современный взгляд на проблему</article-title><trans-title-group xml:lang="en"><trans-title>Bacterial vaginosis: a modern view of the problem</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мурашко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Murashko</surname><given-names>MD, Prof.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мурашко</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Murashko</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First Moscow State Medical University named after I.M. Sechenov, Russia’s Ministry of Health</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2015</year></pub-date><volume>0</volume><issue>11</issue><fpage>80</fpage><lpage>83</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мурашко А.В., Мурашко А.А., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Мурашко А.В., Мурашко А.А.</copyright-holder><copyright-holder xml:lang="en">Murashko M.P., Murashko A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/296">https://www.med-sovet.pro/jour/article/view/296</self-uri><abstract><p>Бактериальный вагиноз (БВ) - одна из наиболее распространенных инфекционных патологий женщин детородного возраста. Бактериальный вагиноз - это состояние, при котором нормальная микрофлора влагалища, представленная в основном лактобактериями, заменяется многочисленной анаэробной и другой условно-патогенной флорой. Установлена связь дисбактериоза с такими осложнениями, как разрыв плодных оболочек, преждевременные роды, инфекции хориона, амниона, околоплодных вод, внутриутробная гибель плода. Это говорит о необходимости проведения скрининга бактериального вагиноза и его лечения до наступления беременности.</p></abstract><trans-abstract xml:lang="en"><p>Bacterial vaginosis (BV) is one of the most common infectious pathologies in women of childbearing age. Bacterial vaginosis is a condition in which the normal vaginal flora represented mostly by lactobacilli is invaded by anaerobic and other opportunistic flora. There is a relationship between dysbacteriosis and complications such as rupture of membranes, premature delivery, infection of the chorion, amnion, amniotic fluid, and intrauterine fetal death. This suggests the need for screening for bacterial vaginosis and its treatment before pregnancy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>бактериальный вагиноз</kwd><kwd>микрофлора лактобактерии</kwd><kwd>диагностика</kwd><kwd>лечение</kwd><kwd>bacterial vaginosis</kwd><kwd>microflora</kwd><kwd>lactobacilli</kwd><kwd>diagnosis</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гродницкая Е.Э. Микробиоценоз влагалища и пути его коррекции у женщин с самопроизвольным прерыванием беременности в поздние сроки гестации в анамнезе. Российский вестник акушера-гинеколога, 2011. 1.</mixed-citation><mixed-citation xml:lang="en">Гродницкая Е.Э. Микробиоценоз влагалища и пути его коррекции у женщин с самопроизвольным прерыванием беременности в поздние сроки гестации в анамнезе. Российский вестник акушера-гинеколога, 2011. 1.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Карапетян Т.Э. Значение оппортунистической инфекции влагалища в развитии внутриутробной инфекции плода и новорожденного (ретроспективное исследование). Акушерство и гинекология, 2010. 4: 59-63.</mixed-citation><mixed-citation xml:lang="en">Карапетян Т.Э. Значение оппортунистической инфекции влагалища в развитии внутриутробной инфекции плода и новорожденного (ретроспективное исследование). Акушерство и гинекология, 2010. 4: 59-63.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Кира Е.Ф. Современные подходы к выбору препарата локального действия в терапии бактериального вагиноза. Акушерство и гинекология, 2012. 7: 59-66.</mixed-citation><mixed-citation xml:lang="en">Кира Е.Ф. Современные подходы к выбору препарата локального действия в терапии бактериального вагиноза. Акушерство и гинекология, 2012. 7: 59-66.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Trama JP, Pascal KE, Zimmerman J, Self MJ, Mordechai E, Adelson ME. Rapid detection of Atopobium vaginae and association with organisms implicated in bacterial vaginosis. Mol Cell Probes, 2008. 22: 96-102.</mixed-citation><mixed-citation xml:lang="en">Trama JP, Pascal KE, Zimmerman J, Self MJ, Mordechai E, Adelson ME. Rapid detection of Atopobium vaginae and association with organisms implicated in bacterial vaginosis. Mol Cell Probes, 2008. 22: 96-102.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ling Z, Kong J, Liu F, Zhu H, Chen X, Wang Y et al. Molecular analysis of the diversity of vaginal microbiota associated with bacterial vaginosis. BMC Genom, 2010. 11: 488.</mixed-citation><mixed-citation xml:lang="en">Ling Z, Kong J, Liu F, Zhu H, Chen X, Wang Y et al. Molecular analysis of the diversity of vaginal microbiota associated with bacterial vaginosis. BMC Genom, 2010. 11: 488.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Кира Е.Ф. Нетрансмиссивные инфекции -новые болезни цивилизации? Акушерство и гинекология, 2008. 5: 61-66.</mixed-citation><mixed-citation xml:lang="en">Кира Е.Ф. Нетрансмиссивные инфекции -новые болезни цивилизации? Акушерство и гинекология, 2008. 5: 61-66.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Allsworth JE, Peipert JF. Prevalence of bacterial vaginosis: 2001-2004 National Health and Nutrition Examination Survey data. Obstet Gynecol, 2007. 109: 114-120.</mixed-citation><mixed-citation xml:lang="en">Allsworth JE, Peipert JF. Prevalence of bacterial vaginosis: 2001-2004 National Health and Nutrition Examination Survey data. Obstet Gynecol, 2007. 109: 114-120.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Кулаков В.И. Практическая гинекология: клинические лекции / под ред. акад. РАМН В.И. Кулакова, проф. В.Н. Прилепской. 4-е изд., доп. М.: МЕД- пресс-информ, 2008. 752 с.</mixed-citation><mixed-citation xml:lang="en">Кулаков В.И. Практическая гинекология: клинические лекции / под ред. акад. РАМН В.И. Кулакова, проф. В.Н. Прилепской. 4-е изд., доп. М.: МЕД- пресс-информ, 2008. 752 с.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Ryckman KK, Simhan HN, Krohn MA, Williams SM. Predicting risk of bacterial vaginosis: The role of race, smoking and corticotropin-releasing hormone-related genes. Mol Hum Reprod, 2009. 15: 31-7.</mixed-citation><mixed-citation xml:lang="en">Ryckman KK, Simhan HN, Krohn MA, Williams SM. Predicting risk of bacterial vaginosis: The role of race, smoking and corticotropin-releasing hormone-related genes. Mol Hum Reprod, 2009. 15: 31-7.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Hickey RJ, Zhou X, Pierson JD, Ravel J, Forney LJ. Understanding vaginal microbiome complexity from an ecological perspective. Transl Res, 2012.160: 267-282.</mixed-citation><mixed-citation xml:lang="en">Hickey RJ, Zhou X, Pierson JD, Ravel J, Forney LJ. Understanding vaginal microbiome complexity from an ecological perspective. Transl Res, 2012.160: 267-282.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Nam H, Whang K, Lee Y. Analysis of vaginal lactic acid producing bacteria in healthy women. J Microbiol, 2007. 45: 515-20.</mixed-citation><mixed-citation xml:lang="en">Nam H, Whang K, Lee Y. Analysis of vaginal lactic acid producing bacteria in healthy women. J Microbiol, 2007. 45: 515-20.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Hil lier S. The complexity of microbial diversity in bacterial vaginosis. N Eng J Med, 2005. 353: 1886-7.</mixed-citation><mixed-citation xml:lang="en">Hil lier S. The complexity of microbial diversity in bacterial vaginosis. N Eng J Med, 2005. 353: 1886-7.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Menard JP, Fenollar F, Henry M, Bretelle F, Raoult D. Molecular quantification of Gardnerella vaginalis and Atopobium vaginae loads to predict bacterial vaginosis. Clin. Infect. Dis., 2008. 47: 33-43.</mixed-citation><mixed-citation xml:lang="en">Menard JP, Fenollar F, Henry M, Bretelle F, Raoult D. Molecular quantification of Gardnerella vaginalis and Atopobium vaginae loads to predict bacterial vaginosis. Clin. Infect. Dis., 2008. 47: 33-43.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Darw i sh A, Elnshar EM, Hamadeh SM, Makarem MH. Treatment options for bacterial vaginosis in patients at high risk of preterm labor and premature rupture of membranes. J Obstet Gynaecol Res., 2007. 33: 781-7.</mixed-citation><mixed-citation xml:lang="en">Darw i sh A, Elnshar EM, Hamadeh SM, Makarem MH. Treatment options for bacterial vaginosis in patients at high risk of preterm labor and premature rupture of membranes. J Obstet Gynaecol Res., 2007. 33: 781-7.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Ворошилина Е.С. Современные возможности диагностики бактериального вагиноза: исследование количественного и качественного состава сложных микробных сообществ. Микробиология, 2011. 13: 70-74.</mixed-citation><mixed-citation xml:lang="en">Ворошилина Е.С. Современные возможности диагностики бактериального вагиноза: исследование количественного и качественного состава сложных микробных сообществ. Микробиология, 2011. 13: 70-74.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Amsel R, Totten PA, Spiegel CA, et al. Nonspecific vaginitis. Diagnostic criteria and microbial and epidemiologic associations. Am J Med, 1983. 74: 14-22.</mixed-citation><mixed-citation xml:lang="en">Amsel R, Totten PA, Spiegel CA, et al. Nonspecific vaginitis. Diagnostic criteria and microbial and epidemiologic associations. Am J Med, 1983. 74: 14-22.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Fredricks DN, Fiedler TL, Marrazzo JM. Molecular identification of bacteria associated with bacterial vaginosis. N Engl J Med, 2005. 353: 1899-911.</mixed-citation><mixed-citation xml:lang="en">Fredricks DN, Fiedler TL, Marrazzo JM. Molecular identification of bacteria associated with bacterial vaginosis. N Engl J Med, 2005. 353: 1899-911.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Livengood CH. Bacterial vaginosis: an overview for 2009. Rev Obstet Gynecol, 2009. 2: 28-37.</mixed-citation><mixed-citation xml:lang="en">Livengood CH. Bacterial vaginosis: an overview for 2009. Rev Obstet Gynecol, 2009. 2: 28-37.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Donati L, Di Vico A, Nucci M, Ouagliozzi L, Spagnuolo T, Labianca A, Bracaglia M, lanniello F, Caruso A, Paradisi G. Vaginal microbial flora and outcome of pregnancy. Arch Gynecol Obstet, 2010. 281: 589-600.</mixed-citation><mixed-citation xml:lang="en">Donati L, Di Vico A, Nucci M, Ouagliozzi L, Spagnuolo T, Labianca A, Bracaglia M, lanniello F, Caruso A, Paradisi G. Vaginal microbial flora and outcome of pregnancy. Arch Gynecol Obstet, 2010. 281: 589-600.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Mitchell CM, Hitti JE, Agnew KJ, Fredricks DN. Comparison of oral and vaginal metronidazole for treatment of bacterial vaginosis in pregnancy: Impact on fastidious bacteria. BMC Infect Dis, 2009. 9: 89.</mixed-citation><mixed-citation xml:lang="en">Mitchell CM, Hitti JE, Agnew KJ, Fredricks DN. Comparison of oral and vaginal metronidazole for treatment of bacterial vaginosis in pregnancy: Impact on fastidious bacteria. BMC Infect Dis, 2009. 9: 89.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Dickey LJ, Nailor MD, Sobel JD. Guidelines for the treatment of bacterial vaginosis: Focus on tinidazole. Ther Clin Risk Manag, 2009. 5: 485-9.</mixed-citation><mixed-citation xml:lang="en">Dickey LJ, Nailor MD, Sobel JD. Guidelines for the treatment of bacterial vaginosis: Focus on tinidazole. Ther Clin Risk Manag, 2009. 5: 485-9.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Decena DC, Co JT, Manalastas RM, Jr, Palaypayon EP, Padolina CS, Sison JM, et al. Metronidazole with Lactacyd vaginal gel in bacterial vaginosis. J Obstet Gynaecol Res, 2006. 32: 243-51.</mixed-citation><mixed-citation xml:lang="en">Decena DC, Co JT, Manalastas RM, Jr, Palaypayon EP, Padolina CS, Sison JM, et al. Metronidazole with Lactacyd vaginal gel in bacterial vaginosis. J Obstet Gynaecol Res, 2006. 32: 243-51.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Schwebke JR, Desmond RA. Tinidazole vs metronidazole for the treatment of bacterial vaginosis. Am J Obstet Gynecol, 2011. 204: 211.e1-e6.</mixed-citation><mixed-citation xml:lang="en">Schwebke JR, Desmond RA. Tinidazole vs metronidazole for the treatment of bacterial vaginosis. Am J Obstet Gynecol, 2011. 204: 211.e1-e6.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Anukam K, Reid G. Probiotics: 100 years (19072007) after Elie Metchnikoffs Observation. Kingsley C Anukam, 2008: 21.</mixed-citation><mixed-citation xml:lang="en">Anukam K, Reid G. Probiotics: 100 years (19072007) after Elie Metchnikoffs Observation. Kingsley C Anukam, 2008: 21.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Delia A, Morgante G, Rago G, Musacchio MC, Petraglia F, De Leo V. Effectiveness of oral administration of Lactobacillus paracasei subsp. paracasei F19 in association with vaginal suppositories of Lactobacillus acidofilus in the treatment of vaginosis and in the prevention of recurrent vaginitis. Minerva Ginecol, 2006. 58: 227-31.</mixed-citation><mixed-citation xml:lang="en">Delia A, Morgante G, Rago G, Musacchio MC, Petraglia F, De Leo V. Effectiveness of oral administration of Lactobacillus paracasei subsp. paracasei F19 in association with vaginal suppositories of Lactobacillus acidofilus in the treatment of vaginosis and in the prevention of recurrent vaginitis. Minerva Ginecol, 2006. 58: 227-31.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Mclean N, Rosenstein IJ. Characterisation and selection of a Lactobacillus species to recolo-nise the vagina of women with recurrent bacterial vaginosis. J Med Microbio, 2000. 49: 543-52.</mixed-citation><mixed-citation xml:lang="en">Mclean N, Rosenstein IJ. Characterisation and selection of a Lactobacillus species to recolo-nise the vagina of women with recurrent bacterial vaginosis. J Med Microbio, 2000. 49: 543-52.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Anukam K, Osazuwa E, Ahonkhai I, Ngwu M, Osemene G, Bruce AW, et al. Augmentation of antimicrobial metronidazole therapy of bacterial vaginosis with oral probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14: randomized, double-blind, placebo controlled trial. Microb Infect, 2006. 8: 1450-4.</mixed-citation><mixed-citation xml:lang="en">Anukam K, Osazuwa E, Ahonkhai I, Ngwu M, Osemene G, Bruce AW, et al. Augmentation of antimicrobial metronidazole therapy of bacterial vaginosis with oral probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14: randomized, double-blind, placebo controlled trial. Microb Infect, 2006. 8: 1450-4.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Martinez RC, Franceschini SA, Patta MC, et al. Improved cure of bacterial vaginosis with single dose of tinidazole (2 g), Lactobacillus rhamnosus GR-1, and Lactobacillus reuteri RC-14: a randomized, double-blind, placebo-controlled trial. Can J Microbiol, 2009. 55: 133-138.</mixed-citation><mixed-citation xml:lang="en">Martinez RC, Franceschini SA, Patta MC, et al. Improved cure of bacterial vaginosis with single dose of tinidazole (2 g), Lactobacillus rhamnosus GR-1, and Lactobacillus reuteri RC-14: a randomized, double-blind, placebo-controlled trial. Can J Microbiol, 2009. 55: 133-138.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Larsson PG, Stray-Pedersen B, Ryttig KR, Larsen S. Human lactobacilli as supplementation of clindamycin to patients with bacterial vagino-sis reduce the recurrence rate; a 6-month, double-blind, randomized, placebo-controlled study. BMC Womens Health, 2008. 8: 3.</mixed-citation><mixed-citation xml:lang="en">Larsson PG, Stray-Pedersen B, Ryttig KR, Larsen S. Human lactobacilli as supplementation of clindamycin to patients with bacterial vagino-sis reduce the recurrence rate; a 6-month, double-blind, randomized, placebo-controlled study. BMC Womens Health, 2008. 8: 3.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Holley RL, Richter HE, Varner RE, Pair L, Schwebke JR. A randomized, double-blind clinical trial of vaginal acidification versus placebo for the treatment of symptomatic bacterial vaginosis. Sex Transm Dis, 2004. 31: 236-238.</mixed-citation><mixed-citation xml:lang="en">Holley RL, Richter HE, Varner RE, Pair L, Schwebke JR. A randomized, double-blind clinical trial of vaginal acidification versus placebo for the treatment of symptomatic bacterial vaginosis. Sex Transm Dis, 2004. 31: 236-238.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Simoes JA, Bahamondes LG, Camargo RP et al. A pilot clinical trial comparing an acid-buffering formulation (ACIDFORM gel) with metronidazole gel for the treatment of symptomatic bacterial vaginosis. Br J Clin Pharmacol, 2006. 61: 211-217.</mixed-citation><mixed-citation xml:lang="en">Simoes JA, Bahamondes LG, Camargo RP et al. A pilot clinical trial comparing an acid-buffering formulation (ACIDFORM gel) with metronidazole gel for the treatment of symptomatic bacterial vaginosis. Br J Clin Pharmacol, 2006. 61: 211-217.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
