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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2019-3-141-147</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-3018</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДИССЕРТАНТ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DISSERTANT</subject></subj-group></article-categories><title-group><article-title>Анализ качества жизни реципиентов печени</article-title><trans-title-group xml:lang="en"><trans-title>Liver recipient quality of life analysis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Космачева</surname><given-names>Е. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kosmacheva</surname><given-names>E. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, завкафедрой терапии №1 факультета повышения квалификации и профессиональной переподготовки специалистов, 350086, г. Краснодар, ул. 1 Мая, д. 167;</p><p>зам. главного врача по мед. части, главный кардиолог Краснодарского края, 350086, г. Краснодар, ул. 1 Мая, д. 167</p></bio><bio xml:lang="en"><p>Dr. of Sci. (Med), Professor, Head of Therapy Depart ment No.1 of the Faculty of Advanced Training and Professional Retraining of Specialists, 350086, Krasnodar, Maya st. 1, 167, Krasnodar;</p><p>deputy Chief Medical Officer for the medical part, 350063, Krasnodar, Sedina St., 4</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабич</surname><given-names>А. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Babich</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-гастроэнтеролог, 350086, г. Краснодар, ул. 1 Мая, д. 167;</p><p>аспирант кафедры терапии №1 факультета повышения квалификации и профессиональной переподготовки специалистов, 350086, г. Краснодар, ул. 1 Мая, д. 167</p></bio><bio xml:lang="en"><p>Gastroenterologist at the Research Institute – Ochapovsky Regional Clinical Hospital No. 1, 350086, Krasnodar, Maya st. 1, 167, Krasnodar;</p><p>Postgraduate student of the Therapy Department No.1 of the Skills Development and Professional Retraining Faculty, 350063, Krasnodar, Sedina St., 4</p></bio><email xlink:type="simple">anna-babich1@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малышева</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Malysheva</surname><given-names>S. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-гастроэнтеролог,</p><p>350086, г. Краснодар, ул. 1 Мая, д. 167</p></bio><bio xml:lang="en"><p>Gastroenterologist,</p><p>350086, Krasnodar, Maya st. 1, 167, Krasnodar</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения «Научно-исследовательский институт – Краевая клиническая больница №1 имени профессора С.В. Очаповского» Министерства здравоохранения Краснодарского края;&#13;
Федеральное государственное бюджетное образовательное учреждение высшего образования «Кубанский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State budgetary institution of public health «Research Institute - Regional Clinical Hospital No.1 named after Professor S.V. Ochapovsky» ofthe Ministry of Health of the Krasnodar Region;&#13;
 Federal State Budgetary Educational Institution of Higher Education «Kuban State Medical University» of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения «Научно-исследовательский институт – Краевая клиническая больница №1 имени профессора С.В. Очаповского» Министерства здравоохранения Краснодарского края;&#13;
Федеральное государственное бюджетное образовательное учреждение высшего образования «Кубанский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State budgetary institution of public health «Research Institute - Regional Clinical Hospital No.1 named after Professor S.V. Ochapovsky» ofthe Ministry of Health of the Krasnodar Region;Federal State Budgetary Educational Institution of Higher Education «Kuban State Medical University» of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения «Научно-исследовательский институт – Краевая клиническая больница №1 имени профессора С.В. Очаповского» Министерства здравоохранения Краснодарского края</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State budgetary institution of public health «Research Institute - Regional Clinical Hospital No.1 named after Professor S.V. Ochapovsky» ofthe Ministry of Health of the Krasnodar Region</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>12</day><month>05</month><year>2019</year></pub-date><volume>0</volume><issue>3</issue><fpage>141</fpage><lpage>147</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Космачева Е.Д., Бабич А.Э., Малышева С.Ю., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Космачева Е.Д., Бабич А.Э., Малышева С.Ю.</copyright-holder><copyright-holder xml:lang="en">Kosmacheva E.D., Babich A.E., Malysheva S.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/3018">https://www.med-sovet.pro/jour/article/view/3018</self-uri><abstract><p>Цель исследования – оценить качество жизни пациентов после трансплантации печени.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Исследовано качество жизни пациентов после проведения трансплантации печени с помощью опросника «SF-36 Health Status Survey» и проведен корреляционный анализ всех шкал опросника с показателями MELD, Child-Pugh до трансплантации, SCORE до и после трансплантации, индексом массы тела, иммуносупрессантами, наличием опухоли, энцефалопатии, гепатита трансплантата.</p></sec><sec><title>Результаты</title><p>Результаты. В обследованной группе по сравнению со здоровыми снижены средние показатели по шкалам «физическое функционирование» на 31,3%, «ролевое функционирование, обусловленное физическим состоянием» – на 60,8%, «интенсивность боли» – на 13,2%, «общее состояние здоровья» – на 33,4%, «жизненная активность» – на 19,9%, «социальное функционирование» – на 19,8%, «ролевое функционирование, обусловленное эмоциональным состоянием» – на 52,9%, «психическое здоровье» – на 11,7%, «физический компонент здоровья» – на 24,5%, «психологический компонент здоровья» – на 15,6%. Между гепатитами трансплантатов и психологическим здоровьем, а также между наличием опухолей и интенсивностью боли коэффициент корреляции сопряженности больше чем 0,25, а уровни значимости обоих критериев Хи-квадрат меньше чем 0,05.</p></sec><sec><title>Выводы</title><p>Выводы. Реципиенты печени в сравнении со здоровыми обладают наиболее низким уровнем качества жизни по шкале ролевого функционирования, обусловленного физическим состоянием. Выявлена умеренная статистически значимая взаимосвязь между гепатитами трансплантатов и психологическим здоровьем, а также наличием опухолей и интенсивностью боли. Гендерных отличий по всем компонентам КЖ в группе реципиентов печени нет. </p></sec></abstract><trans-abstract xml:lang="en"><p>The aim of the study – to evaluate the quality of life of patients after liver transplantation.</p><sec><title>Patients and methods</title><p>Patients and methods. The quality of life of patients after liver transplantation was studied with the help of «SF-36 Health Status Survey» questionnaire and correlation analysis of all scales of the questionnaire with the MELD indices, Child-Pugh before transplantation, SCORE before and after transplantation, body mass index, immunosuppressants, presence of tumor, encephalopathy, hepatitis transplant was performed.</p></sec><sec><title>The results</title><p>The results. In the surveyed group, the average indicators on the scales «physical functioning» were reduced by 31.3%, «role functioning due to physical condition» - by 60.8%, «pain intensity» - by 13.2%, «general health condition» - by 33.4%, «Life activity» by 19.9%, «social functioning» by 19.8%, «emotional role functioning» by 52.9%, «mental health» by 11.7%, «physical component of health» by 24.5% and «psychological component of health» by 15.6%. Between hepatitis grafts and psychological health, as well as between the presence of tumors and pain intensity, the correlation coefficient is greater than 0.25, and the significance levels of both chi-square criteria are less than 0.05.</p></sec><sec><title>Conclusions</title><p>Conclusions. Liver recipients have the lowest quality of life on the role-playing scale due to their physical condition compared to healthy liver recipients. A moderate statistically significant relationship between hepatitis grafts and psychological health, as well as the presence of tumors and pain intensity, has been revealed. There are no gender differences in all components of QL in the group of liver recipients. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>трансплантация печени</kwd><kwd>качество жизни</kwd><kwd>пол</kwd><kwd>опросник SF-36</kwd></kwd-group><kwd-group xml:lang="en"><kwd>liver transplantation</kwd><kwd>quality of life</kwd><kwd>sex</kwd><kwd>SF-36 questionnaire</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дзуева С.С., Ахубекова З.А., Жамборова Ф.А., Арамисова Р.М. Оценка качества жизни при сердечно-сосудистых заболеваниях. Трудный пациент. 2018;10(16):6-9.</mixed-citation><mixed-citation xml:lang="en">Dzueva S.S., Akhubekova Z.A., Zhamborova F.A., Aramisova R.M. Assessment of quality of life in cardiovascular diseases. Difficult patient [Trudnyj pacient]. 2018;10(16):6-9. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Новик А.А., Ионова Т.И., Руководство по исследованию качества жизни в медицине. Под ред. Шевченко Ю.Л. 2-е изд. М.: ОЛМА Медиа Групп, 2007.</mixed-citation><mixed-citation xml:lang="en">Novik A.A., Ionova T.I., Guidelines for Quality of Life Research in Medicine. Edited by Y.L. Shevchenko, 2nd ed. M.: OLMA Media Group, 2007. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Готье С.В., Хомяков С.М. Донорство и трансплантация органов в Российской Федерации в 2017 году. Сообщение регистра Российского трансплантологического общества. Вестник трансплантологии и искусственных органов. 2018;XX(2):6-28.</mixed-citation><mixed-citation xml:lang="en">Gautier S.V., Khomyakov S.M. Donorship and organ transplantation in the Russian Federation in 2017. Report from the register of the Russian Transplant Society. Herald of transplantology and artificial organs [Vestnik transplantologii i iskusstvennyh organov]. 2018;XX(2):6-28. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Onghena L., Develtere W., Poppe C. Et al. Quality of life after liver transplantation: State of the art. World J Hepatol. 2016;8(18):749-756.</mixed-citation><mixed-citation xml:lang="en">Onghena L., Develtere W., Poppe C. Et al. Quality of life after liver transplantation: State of the art. World J Hepatol. 2016;8(18):749-756.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Solak O., Yaman F., Ulasli A.M. et al. Improvement in Quality of Life, Functional Capacity, and Depression Level after Cardiac Rehabilitation. Turkish Journal of Medical Rehabilitation. 2015;61:130–136.</mixed-citation><mixed-citation xml:lang="en">Solak O., Yaman F., Ulasli A.M. et al. Improvement in Quality of Life, Functional Capacity, and Depression Level after Cardiac Rehabilitation. Turkish Journal of Medical Rehabilitation. 2015;61:130–136.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Тихомирова Н.Ю., Елисеева Л.Н., Федорова Н.П. и др. Оценка качества жизни у лиц молодого возраста с недифференцированной дисплазией соединительной ткани и артралгиями по опроснику SF-36. Медицинские науки. Фундаментальные исследования. 2014;10:1191-1194.</mixed-citation><mixed-citation xml:lang="en">Tikhomirova N.Y., Eliseeva L.N., Fedorova N.P., etc. Assessment of quality of life in young people with undifferentiated connective tissue dysplasia and arthralgia according to the SF-36 questionnaire. Medical sciences. Fundamental research [Medicinskie nauki. Fundamental’nye issledovanija]. 2014;10:1191-1194. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Шевченко А.О., Халилулин Т.А., Миронков Б.Л. и др. Оценка качества жизни пациентов с трансплантированным сердцем. Трансплантация органов. 2014;16(4):45–50.</mixed-citation><mixed-citation xml:lang="en">Shevchenko A.O., Khalilulin T.A., Mironkov B.L. and others. Assessment of the quality of life of patients with transplanted heart. Organ transplantation [Transplantacija organov]. 2014;16(4):45–50. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Kostro J.Z., Hellmann A., Kobiela J. et al. Quality of Life After Kidney Transplantation: A Prospective Study. Transplant Proc. 2016;48(1):50-4.</mixed-citation><mixed-citation xml:lang="en">Kostro J.Z., Hellmann A., Kobiela J. et al. Quality of Life After Kidney Transplantation: A Prospective Study. Transplant Proc. 2016;48(1):50-4.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Lønning K., Heldal K., Bernklev T. et al. Improved Health-Related Quality of Life in Older Kidney Recipients 1 Year After Transplantation. Transplantation Direct. 2018 April;4(4):351.</mixed-citation><mixed-citation xml:lang="en">Lønning K., Heldal K., Bernklev T. et al. Improved Health-Related Quality of Life in Older Kidney Recipients 1 Year After Transplantation. Transplantation Direct. 2018 April;4(4):351.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Burra P., Ferrarese A., Feltring G. Quality of life and adherence in liver transplant recipients. Minerva Gastroenterol Dietol. 2017.</mixed-citation><mixed-citation xml:lang="en">Burra P., Ferrarese A., Feltring G. Quality of life and adherence in liver transplant recipients. Minerva Gastroenterol Dietol. 2017.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Martín-Rodríguez A., Pérez-San-Gregorio M.A., Domínguez-Cabello E., et al. Biopsychosocial functioning among cirrhotic patients in various stages of transplant process in comparison to liver transplant recipients. Ann Psicol-Spain. 2014;30:83–92.</mixed-citation><mixed-citation xml:lang="en">Martín-Rodríguez A., Pérez-San-Gregorio M.A., Domínguez-Cabello E., et al. Biopsychosocial functioning among cirrhotic patients in various stages of transplant process in comparison to liver transplant recipients. Ann Psicol-Spain. 2014;30:83–92.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Phillips A.L., Walker E.L., Martin J.E. et al. Quality of Life as a Predictor of Morbidity, Mortality, and Resource Utilization After Solid Organ Transplant. Transplantation Proceedings. 1922;2001:33.</mixed-citation><mixed-citation xml:lang="en">Phillips A.L., Walker E.L., Martin J.E. et al. Quality of Life as a Predictor of Morbidity, Mortality, and Resource Utilization After Solid Organ Transplant. Transplantation Proceedings. 1922;2001:33.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Готье С.В., Климушева Н.Ф. Психологическая адаптация и реабилитация реципиентов донорских органов. Вестник трансплантологии и искусственных органов. 2016;18(2):37- 45.</mixed-citation><mixed-citation xml:lang="en">Gauthier S.V., Klimusheva N.F. Psychological adaptation and rehabilitation of recipients of donor organs. Herald of transplantology and artificial organs [Vestnik transplantologii i iskusstvennyh organov].2016;18(2):37-45. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Кухарев Д.Ю., Вечера Е.А., Сверчинская А.А. и др. Трансплантация печени как способ улучшения качества жизни детей с билиарной атрезией. Молодой ученый. 2018;14(200):128- 130.</mixed-citation><mixed-citation xml:lang="en">Kukharev D.Y., Vechera E.A., Sverchinskaya A.A. and others. Liver transplantation as a way to improve the quality of life of children with biliary atresia. Young scientist [Molodoj uchenyj]. 2018;14(200):128-130. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Lobo E., Stiefel F., Söllner W. et al. Care complexity, mood, and quality of life in liver pretransplant patients. Clin Transplant. 2013;27:417-425.</mixed-citation><mixed-citation xml:lang="en">Lobo E., Stiefel F., Söllner W. et al. Care complexity, mood, and quality of life in liver pretransplant patients. Clin Transplant. 2013;27:417-425.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Dąbrowska-Bender M., Kozaczuk A., Pączek L., Milkiewicz P., Słoniewski R., Staniszewska A. Patient Quality of Life After Liver Transplantation in Terms of Emotional Problems and the Impact of Sociodemographic Factors. Transplant Proc. 2018;50(7):2031-2038.</mixed-citation><mixed-citation xml:lang="en">Dąbrowska-Bender M., Kozaczuk A., Pączek L., Milkiewicz P., Słoniewski R., Staniszewska A. Patient Quality of Life After Liver Transplantation in Terms of Emotional Problems and the Impact of Sociodemographic Factors. Transplant Proc. 2018;50(7):2031-2038.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Louis O., Wouter D., Carine P., Anja G., Roberto T., Aude V. Quality of life after liver transplantation: State of the art. World J Hepatol. 2016;8(18):749-756.</mixed-citation><mixed-citation xml:lang="en">Louis O., Wouter D., Carine P., Anja G., Roberto T., Aude V. Quality of life after liver transplantation: State of the art. World J Hepatol. 2016;8(18):749-756.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Орлов В.А., Гиляревский С.Р. Проблемы изучения качества жизни в современной медицине: обзорная информация. М., 1992.</mixed-citation><mixed-citation xml:lang="en">Orlov V.A., Gilyarevsky S.R. Problems of studying the quality of life in modern medicine: overview information. М., 1992. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Petrucci L., Ricotti S., Michelini I. et al. Return to work after thoracic organ transplantation in a clinically-stable population. The European Heart Journal of Heart Failure. 2007;9:1112–1119.</mixed-citation><mixed-citation xml:lang="en">Petrucci L., Ricotti S., Michelini I. et al. Return to work after thoracic organ transplantation in a clinically-stable population. The European Heart Journal of Heart Failure. 2007;9:1112–1119.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Albert W., Hudalla A., Traue K., Hetzer R. Impact of heart transplantation in infancy and adolescence on quality of life and compliance. HSR Proceedings in Intensive Care and Cardiovascular Anesthesia. 2012;4(2):125–128.</mixed-citation><mixed-citation xml:lang="en">Albert W., Hudalla A., Traue K., Hetzer R. Impact of heart transplantation in infancy and adolescence on quality of life and compliance. HSR Proceedings in Intensive Care and Cardiovascular Anesthesia. 2012;4(2):125–128.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Величко Н.А., Некрасов А.Ю., Агапов В.К., Сергеев А.В. Оценка качества жизни пациентов пожилого и старческого возраста после различных видов холецистэктомии по поводу острого деструктивного холецистита. Вестник Ивановской академии. 2015;4(20):28-3.</mixed-citation><mixed-citation xml:lang="en">Velichko N.A., Nekrasov A.Y., Agapov V.K., Sergeev A.V. Assessment of the quality of life of elderly and senile patients after various types of cholecystectomy for acute destructive cholecystitis. Herald of the Ivanovo Academy [Vestnik Ivanovskoj akademii]. 2015;4(20):28-3. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Щербаков Д.В., Власенко Н.Ю., Бельский В.В. и др. Изучение качества жизни пациентов с болезнями системы кровообращения на этапе реабилитации. Современные проблемы науки и образования. 2015;4:12-16.</mixed-citation><mixed-citation xml:lang="en">Scherbakov D.V., Vlasenko N.Y., Belsky V.V., etc. Study of the quality of life of patients with circulatory system diseases at the stage of rehabilitation. Modern problems of science and education [Sovremennye problemy nauki i obrazovanija]. 2015;4:12-16. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Шелехова Т.Ю., Ачкасов Е.Е., Цирульникова О.М., Володина К.А. Дозированная ходьба как метод повышения физической активности и улучшения качества жизни реципиентов донорской почки. Клиническая медицина. 2017;12(95):1122-1126.</mixed-citation><mixed-citation xml:lang="en">Shelekhova T.Y., Achkasov E.E., Tsirulnikova O.M., Volodina K.A. Dosed walking as a method of increasing physical activity and improving the quality of life of kidney recipients. Clinical medicine [Klinicheskaja medicina]. 2017;12(95):1122- 1126. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Жирнова Т.Ю., Ачкасов Е.Е., Цирульникова О.М. и др. Влияние физической реабилитации на качество жизни после трансплантации почки. Вестник Российской академии медицинских наук. 2014;3-4(69):65-70.</mixed-citation><mixed-citation xml:lang="en">Zhirnova T.Y., Achkasov E.E., Tsirulnikova O.M., etc. Influence of physical rehabilitation on the quality of life after kidney transplantation. Bulletin of the Russian Academy of Medical Sciences [Vestnik Rossijskoj akademii medicinskih nauk]. 2014;3- 4(69):65-70. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Brazier J.E., Harper R., Jones N.M. et al. Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ. 1992;305:160–164.</mixed-citation><mixed-citation xml:lang="en">Brazier J.E., Harper R., Jones N.M. et al. Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ. 1992;305:160–164.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Hellgren A., Berglund B., Gunnarsson U. et al. Health-related quality of life after liver transplantation. Liver Transplant Surg. 1998;4:215–221.</mixed-citation><mixed-citation xml:lang="en">Hellgren A., Berglund B., Gunnarsson U. et al. Health-related quality of life after liver transplantation. Liver Transplant Surg. 1998;4:215–221.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">McHorney C.A., Ware Jr J.E., Lu J.F., Sherbourne C.D. The MOS 36-item Short-Form Health Survey (SF-36): III. Tests of data quality, scaling assumptions, and reliability across diverse patient groups. Med Care. 1994;32:40–66.</mixed-citation><mixed-citation xml:lang="en">McHorney C.A., Ware Jr J.E., Lu J.F., Sherbourne C.D. The MOS 36-item Short-Form Health Survey (SF-36): III. Tests of data quality, scaling assumptions, and reliability across diverse patient groups. Med Care. 1994;32:40–66.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">McHorney C.A., Ware Jr J.E., Raczek A.E. The MOS 36-Item ShortForm Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. Med Care. 1993;31:247–263.</mixed-citation><mixed-citation xml:lang="en">McHorney C.A., Ware Jr J.E., Raczek A.E. The MOS 36-Item ShortForm Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. Med Care. 1993;31:247–263.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Stewart A.L., Hays R.D., Ware Jr J.E. The MOS short-form general health survey. Reliability and validity in a patient population. Med Care. 1988;26:724–735.</mixed-citation><mixed-citation xml:lang="en">Stewart A.L., Hays R.D., Ware Jr J.E. The MOS short-form general health survey. Reliability and validity in a patient population. Med Care. 1988;26:724–735.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Cannesson A., Boleslawski E., Declerck N. et al. Daily life, pregnancy, and quality of life after liver transplantation. Presse Med. 2009;38:1319-1324.</mixed-citation><mixed-citation xml:lang="en">Cannesson A., Boleslawski E., Declerck N. et al. Daily life, pregnancy, and quality of life after liver transplantation. Presse Med. 2009;38:1319-1324.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Bianco T., Cillo U., Amodio P. et al. Gender Differences in the Quality of Life of Patients with Liver Cirrhosis Related to Hepatitis C after Liver Transplantation. Blood Purificationю 2013;36:231-236.</mixed-citation><mixed-citation xml:lang="en">Bianco T., Cillo U., Amodio P. et al. Gender Differences in the Quality of Life of Patients with Liver Cirrhosis Related to Hepatitis C after Liver Transplantation. Blood Purificationю 2013;36:231-236.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Cowling T., Jennings L.W., Goldstein M.R. Liver Transplantation and health – related quality of life; scoring differences between men and women. Liver Transplantation. 2004;10:88-96.</mixed-citation><mixed-citation xml:lang="en">Cowling T., Jennings L.W., Goldstein M.R. Liver Transplantation and health – related quality of life; scoring differences between men and women. Liver Transplantation. 2004;10:88-96.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Blanch J., Sureda B., Flavia M. et al. Psychosocial adjustment to orthotopic liver in 266 recipients. Liver Transplantation. 2004;10:228-234.</mixed-citation><mixed-citation xml:lang="en">Blanch J., Sureda B., Flavia M. et al. Psychosocial adjustment to orthotopic liver in 266 recipients. Liver Transplantation. 2004;10:228-234.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Desai R., Jamieson N.V., Gimson A.E. et al. Quality of Life up to 30 years Following Liver Transplantation. Liver Transplantation. 2008;14:1473-1479.</mixed-citation><mixed-citation xml:lang="en">Desai R., Jamieson N.V., Gimson A.E. et al. Quality of Life up to 30 years Following Liver Transplantation. Liver Transplantation. 2008;14:1473-1479.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Kotarska K., Wunsch E., Kempińska – Podhordecka A. et al. Factors Affecting HealthRelated Quality of Life and Physical Activity after Liver Transplantation for Autoimmune and Nonautoimmune Liver Diseases: A Prospective, Single Centre Study. Journal of Immunology Research. 2014;9.</mixed-citation><mixed-citation xml:lang="en">Kotarska K., Wunsch E., Kempińska – Podhordecka A. et al. Factors Affecting HealthRelated Quality of Life and Physical Activity after Liver Transplantation for Autoimmune and Nonautoimmune Liver Diseases: A Prospective, Single Centre Study. Journal of Immunology Research. 2014;9.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Saab S., Bownik H., Ayoub N. et al. Differences in Health-Related Quality of Life Scores After Orthotopic Liver Transplantation With Respect to Selected Socioeconomic Factors. Liver Transplantation. 2011;17(5):580-590.</mixed-citation><mixed-citation xml:lang="en">Saab S., Bownik H., Ayoub N. et al. Differences in Health-Related Quality of Life Scores After Orthotopic Liver Transplantation With Respect to Selected Socioeconomic Factors. Liver Transplantation. 2011;17(5):580-590.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Zahn A., Seubert L., Jűnger J. et al. Factors influencing long-term quality of life and depression in German liver transplant recipients: A singlecentre cross-sectional study. Annals of Transplantation. 2013;18:327-335.</mixed-citation><mixed-citation xml:lang="en">Zahn A., Seubert L., Jűnger J. et al. Factors influencing long-term quality of life and depression in German liver transplant recipients: A singlecentre cross-sectional study. Annals of Transplantation. 2013;18:327-335.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Beyer N., Aadahl M., Strange B. et al. Improved physical performance after orthotopic liver transplantation. Liver Transpl Surg. 1999;5:301.</mixed-citation><mixed-citation xml:lang="en">Beyer N., Aadahl M., Strange B. et al. Improved physical performance after orthotopic liver transplantation. Liver Transpl Surg. 1999;5:301.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Комелягина Е.Ю., Уварова О.М., Анциферов М.Б. Русскоязычная версия опросника для оценки качества жизни больных с периферической полинейропатией: валидация и перспективы применения. Сахарный диабет. 2014;(2):56-65.</mixed-citation><mixed-citation xml:lang="en">Komeliagina E.Y., Uvarova O.M., Antsiferov M.B. Russian version of the questionnaire for assessment of the quality of life of patients with peripheral polyneuropathy: validation and prospects of application. Diabetes mellitus [Saharnyj diabet]. 2014;(2):56- 65. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Шелехова Т.Ю., Ачкасов Е.Е., Цирульникова О.М. и др. Спорт для пациентов с трансплантированными органами. Вестник трансплантологии и искусственных органов. 2018;3(20):6-12.</mixed-citation><mixed-citation xml:lang="en">Shelekhova T.Y., Achkasov E.E., Tsirulnikova O.M., etc. Sports for patients with transplanted organs. Herald of transplantology and artificial organs [Vestnik transplantologii i iskusstvennyh organov]. 2018;3(20):6-12. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Krasnoff J.B., Vintro A.Q., Ascher N.I. et al. Obectives measures of health – related quality of life over 24 months post – liver transplantation. Clinical Transplantation. 2005;19(1):1-9.</mixed-citation><mixed-citation xml:lang="en">Krasnoff J.B., Vintro A.Q., Ascher N.I. et al. Obectives measures of health – related quality of life over 24 months post – liver transplantation. Clinical Transplantation. 2005;19(1):1-9.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Готье С.В., Ачкасов Е.Е., Шилов Е.М. и др. Физическая реабилитация в трансплантологии (обзор литературы). Нефрология и диализ. 2013;3(15):200-208.</mixed-citation><mixed-citation xml:lang="en">Gauthier  S.V., Achkasov E.E., Shilov E.M., etc. Physical rehabilitation in transplantology (literature review). Nephrology and dialysis [Nefrologija i dializ]. 2013;3(15):200-208. (In Russ.)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
