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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2019-11-89-94</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-3087</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БРОНХОПУЛЬМОНОЛОГИЯ, ЛОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BRONCHOPULMONOLOGY, ENT</subject></subj-group></article-categories><title-group><article-title>Лечение респираторных заболеваний с использованием пластырей для ингаляций</article-title><trans-title-group xml:lang="en"><trans-title>Treatment of respiratory diseases with inhalation patches</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Старостина</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Starostina</surname><given-names>L S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Старостина Лада Сергеевна – кандидат медицинских наук, педиатр, пульмонолог, неонатолог Университетской клинической детской больницы, доцент кафедры детских болезней лечебного факультета</p><p>119991, г. Москва, ул. Трубецкая, д. 8, стр. 2; 119991, Москва, ул. Б. Пироговская, д. 6, стр. 1</p></bio><bio xml:lang="en"><p>Starostina Lada Sergeevna – Cand. of Sci. (Med.), Pediatrician, Pulmonologist, Neonatologist of University Clinical Children’s Hospital, Associate Professor of Chair for Pediatric Diseases at Medical Faculty</p><p>119991,  Moscow, Trubetskaya Street, 8, p. 2, 119991, Moscow, B. Pirogovskaya St., 6, Bldg. 1 </p></bio><email xlink:type="simple">Starostina-ls@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное автономное образовательное учреждение высшего образования «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health of the Russian Federation (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>16</day><month>07</month><year>2019</year></pub-date><volume>0</volume><issue>11</issue><fpage>89</fpage><lpage>94</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Старостина Л.С., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Старостина Л.С.</copyright-holder><copyright-holder xml:lang="en">Starostina L.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/3087">https://www.med-sovet.pro/jour/article/view/3087</self-uri><abstract><p>Высокая заболеваемость респираторными инфекциями в раннем возрасте требует постоянного внимания врачей различных специальностей. Необходимо помнить об особенностях развития дыхательных путей у детей раннего возраста, воздействия лекарственных веществ на слизистую оболочку и мерцательный эпителий. А также учитывать возможность использования разных методов введения лекарственных веществ для профилактики и лечения респираторных инфекций с учетом возраста ребенка, эффективности воздействия и снижения риска развития побочных реакций.</p></abstract><trans-abstract xml:lang="en"><p>The high incidence of respiratory infections at an early age requires constant attention of doctors of various specialties. It should be born in mind that the development of the respiratory tract in young children has unique features, and that different drugs can have different effects on the mucous membrane and ciliated epithelium. Also take into account the possibility of using different ways drugs can be administered to prevent and treat respiratory infections with due account for the age of the child, the effectiveness of action and adverse events risk reduction.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>респираторные инфекции</kwd><kwd>дыхательные пути</kwd><kwd>слизистая оболочка</kwd><kwd>мерцательный эпителий</kwd><kwd>ингаляция</kwd><kwd>ароматерапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>respiratory infections</kwd><kwd>respiratory tract</kwd><kwd>mucosa</kwd><kwd>ciliated epithelium</kwd><kwd>inhalation</kwd><kwd>aromatherapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Радциг Е.Ю., Богомильский М.Р., Лаберко Е.Л., Ермилова Н.В. Взаимосвязь возрастных особенностей строения слизистой оболочки полости носа и способов введения препаратов для лечения острого инфекционного ринита у детей и подростков. Педиатрия им. Г.Н. Сперанского. 2012 Т. 91;(4):83-88</mixed-citation><mixed-citation xml:lang="en">Radcig E.Yu., Bogomil’skij M.R., Laberko E.L., Ermilova N.V. Vzaimosvyaz’ vozrastnyh osobennostej stroeniya slizistoj obolochki polosti nosa i sposobov vvedeniya preparatov dlya lecheniya ostrogo infekcionnogo rinita u detej i podrostkov. Pediatriya im. G.N. Speranskogo. 2012 T. 91;(4):83-8 (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Сагалович Е.М. Физиология и патофизиология верхних дыхательных путей. М.: Медицина, 1967. 328 с.</mixed-citation><mixed-citation xml:lang="en">Sagalovich E. M. Physiology and pathophysiology of the upper respiratory tract. M.: Medicine, 1967. 328 p. (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Пискунов Г.З., Пискунов С.З. Клиническая ринология. М.: ГЭОТАР-Медиа, 2007. 800 c.</mixed-citation><mixed-citation xml:lang="en">Piskunov G. Z., Piskunov S. Z. Clinical rhinology. M.: GEOTAR-Media, 2007. 800 p. (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Dalhamm T, Holma B, Tomenius L. In vitro studies of the ciliotoxic action of ethanol vapour in relation to its concentration in tracheal tissue. Acta Pharmacol. Toxicol. (Copenh). 1967;25 (2):272-280.</mixed-citation><mixed-citation xml:lang="en">Dalhamm T, Holma B, Tomenius L. In vitro studies of the ciliotoxic action of ethanol vapour in relation to its concentration in tracheal tissue. Acta Pharmacol. Toxicol. (Copenh). 1967;25 (2):272-280.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Alberty J, Stoll W. The effect of antiallergic intranasal formulations on ciliary beat frequency of human nasal epithelium in vitro. Allergy. 1998;53(10):986-989.</mixed-citation><mixed-citation xml:lang="en">Alberty J, Stoll W. The effect of antiallergic intranasal formulations on ciliary beat frequency of human nasal epithelium in vitro. Allergy. 1998;53(10):986-989.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Inanli S, Ozturk O, Korkmaz M, Tutkun A. The effects of topical agents of fluticasone propionate, oxymetazoline, and 3% and 0,9 % sodium chloride solutions on mucociliary clearance in the therapy of acute bacterial rhinosinusitis in vivo. Laryngoscope. 2002;112(2): 320-325.</mixed-citation><mixed-citation xml:lang="en">Inanli S, Ozturk O, Korkmaz M, Tutkun A. The effects of topical agents of fluticasone propionate, oxymetazoline, and 3% and 0,9 % sodium chloride solutions on mucociliary clearance in the therapy of acute bacterial rhinosinusitis in vivo. Laryngoscope. 2002;112(2): 320-325.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Mickenhagen A, Siefer O, Neugebauer P, Stennert E. The influence of different alphasympathomimetic drugs and benzalkoniumchlorid on the ciliary beat frequency of in vitro cultured human nasal mucosa cells. Laryngorhinootologie. 2008;87(1):30-38.</mixed-citation><mixed-citation xml:lang="en">Mickenhagen A, Siefer O, Neugebauer P, Stennert E. The influence of different alphasympathomimetic drugs and benzalkoniumchlorid on the ciliary beat frequency of in vitro cultured human nasal mucosa cells. Laryngorhinootologie. 2008;87(1):30-38.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Gosepath J, Grebneva N, Mossikhin S, Mann WJ. Topical antibiotic, antifungal, and antiseptic solutions decrease ciliary activity in nasal respiratory cells. Am. J. Rhinol. 2002;16(1):25-31.</mixed-citation><mixed-citation xml:lang="en">Gosepath J, Grebneva N, Mossikhin S, Mann WJ. Topical antibiotic, antifungal, and antiseptic solutions decrease ciliary activity in nasal respiratory cells. Am. J. Rhinol. 2002;16(1):25-31.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Remigius UA, Jorissen M, Willems T, Kinget R. Mechanistic appraisal of the effects of some protease inhibitors on ciliary beat frequency in a sequential cell culture system of human nasal epithelium. Eur. J. Pharm. Biopharm. 2003;55(3):283-289.</mixed-citation><mixed-citation xml:lang="en">Remigius UA, Jorissen M, Willems T, Kinget R. Mechanistic appraisal of the effects of some protease inhibitors on ciliary beat frequency in a sequential cell culture system of human nasal epithelium. Eur. J. Pharm. Biopharm. 2003;55(3):283-289.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Boek WM, Romeijn SG, Graamans K, Verhoef JC. Validation of animal experiments on ciliary function in vitro. I. The influence of substances used clinically. Acta Otolaryngol. 1999;119(1):93-97.</mixed-citation><mixed-citation xml:lang="en">Boek WM, Romeijn SG, Graamans K, Verhoef JC. Validation of animal experiments on ciliary function in vitro. I. The influence of substances used clinically. Acta Otolaryngol. 1999;119(1):93-97.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang L, Han D, Song X, Wang K. Effect of oxymetazoline on healthy human nasal ciliary beat frequency measured with high-speed digital microscopy and mucociliary transport time. Ann. Otol. Rhinol. Laryngol. 2008;117(2):127-133.</mixed-citation><mixed-citation xml:lang="en">Zhang L, Han D, Song X, Wang K. Effect of oxymetazoline on healthy human nasal ciliary beat frequency measured with high-speed digital microscopy and mucociliary transport time. Ann. Otol. Rhinol. Laryngol. 2008;117(2):127-133.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Петров В.В., Молдавская А.А., Аведисян В.Э. Морфогенез слизистой оболочки полости носа человека в раннем постнатальном онтогенезе и его клинические аспекты. Издательство АГМА, Астрахань, 2007</mixed-citation><mixed-citation xml:lang="en">Petrov V. V., Moldavian A. A., Avedisyan V. E. Morphogenesis of the mucous membrane of the human nasal cavity in early postnatal ontogenesis and its clinical aspects. AGMA publishing house, Astrakhan, 2007 (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">http://tonus.by/velnes/aromaterapiya/istoriyaaromaterapiichast-1-drevnie-civilizacii.html</mixed-citation><mixed-citation xml:lang="en">http://tonus.by/velnes/aromaterapiya/istoriyaaromaterapiichast-1-drevnie-civilizacii.html</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Саков И.В. Материалы V научно-практической конференции «Аромакоррекция психофизического состояния человека». Никитский ботанический сад – национальный научный центр. Ялта.: ИП Цветков С.Л., 2015:107-113.</mixed-citation><mixed-citation xml:lang="en">Sakov I. V. Materials of the V scientific-practical conference «aroma Correction of human psychophysical state». Nikitsky Botanical garden – national scientific center. Yalta.: SP Tsvetkov S. L., 2015:107-113 (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Радциг Е.Ю., Ермилова Н.В., Сапаева Н.В., Богомильский М.Р. Альтернатива топическим деконгестантам в симптоматической терапии острых ринитов у детей. Вопросы современной педиатрии. 2007;5:48-51</mixed-citation><mixed-citation xml:lang="en">Radzig E. Yu., Ermilova N. In. Sapaeva N. In. Bogomilsky M. R. Alternative to topical decongestants in symptomatic therapy of acute rhinitis in children. Questions modern Pediatrics. 2007;5:48-51 (In Russ).</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Старостина Л.С. Варианты муколитической терапии кашля. РМЖ «Медицинское обозрение». 2019;3:60-64</mixed-citation><mixed-citation xml:lang="en">Starostina L.S. Options mucolytic therapy cough. RMJ «Medical review», 2019;3:60-64 (In Russ).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
