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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2019-4-24-29</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-3111</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>САХАРНЫЙ ДИАБЕТ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DIABETES MELLITUS</subject></subj-group></article-categories><title-group><article-title>Клинические аспекты и перспективы применения ингибиторов ДПП-4</article-title><trans-title-group xml:lang="en"><trans-title>Clinical aspects and prospects of using DPP-4 inhibitors</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бирюкова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Biryukova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бирюкова Елена Валерьевна - доктор медицинских наук, профессор кафедры эндокринологии и диабетологии.</p><p>127473, Москва, ул. Делегатская, д. 20, стр. 1</p></bio><bio xml:lang="en"><p>Biryukova Elena Valeryevna - Dr. of Sci. (Med), Professor of the Department of Endocrinology and Diabetology.</p><p>127473, Moscow, 20, Delegateskaya St., b. 1</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное образовательное учреждение высшего образования «Московский государственный медикостоматологический университет имени А.И. Евдокимова» Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Educational Institution of the Higher Education «Moscow State University of Medicine and Dentistry named after A.I. Yevdokimov» of the Ministry of Healthcare of the Russian Federation<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>20</day><month>08</month><year>2019</year></pub-date><volume>0</volume><issue>4</issue><fpage>24</fpage><lpage>29</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бирюкова Е.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Бирюкова Е.В.</copyright-holder><copyright-holder xml:lang="en">Biryukova E.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/3111">https://www.med-sovet.pro/jour/article/view/3111</self-uri><abstract><p>Сахарный диабет 2 типа - тяжелое заболевание, связанное с развитием тяжелых осложнений. Последние успехи в области диабетологии связаны с инкретин-направленной терапией. Обсуждается механизм действия ингибиторов ДПП-4.Представлены результаты клинических исследований эффективности и безопасности гозоглиптина.</p></abstract><trans-abstract xml:lang="en"><p>Type 2 diabetes mellitus is a serious disease associated with the development of severe complications. Recent advances in diabetology are related to hormone therapy. The mechanism of action of DPP-4 inhibitors is discussed. The results of clinical studies of the efficacy and safety of gosogliptine are presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет 2 типа</kwd><kwd>сосудистые осложнения</kwd><kwd>сахароснижающая терапия</kwd><kwd>ингибиторы ДПП-4</kwd><kwd>гозоглиптин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>type 2 diabetes mellitus</kwd><kwd>vascular complications</kwd><kwd>sugar-reducing therapy</kwd><kwd>DPP-4 inhibitors</kwd><kwd>gosogliptine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Алгоритмы специализированной медицинской помощи больных сахарным диабетом. Под редакцией И.И. Дедова, М.В. Шестаковой, А.Ю. Майорова. 9-й выпуск. М., 2019.</mixed-citation><mixed-citation xml:lang="en">Algorithms of specialized medical care for patients with diabetes mellitus. Edited by I.I. Dedov, M.V. Shestakova, A.Yu. Mayorov. 9th issue. М., 2019. 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