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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2019-4-94-102</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-3122</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДРУГИЕ ПРОБЛЕМЫ ЭНДОКРИНОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OTHER PROBLEMS OF ENDOCRINOLOGY</subject></subj-group></article-categories><title-group><article-title>Ожирение как фактор онкологического риска. Обзор литературы</article-title><trans-title-group xml:lang="en"><trans-title>Obesity as an oncological risk factor. Literature review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Салухов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Salukhov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Салухов Владимир Владимирович – доктор медицинских наук, начальник 1-й кафедры и клиники (терапии усовершенствования врачей).</p></bio><bio xml:lang="en"><p>Salukhov Vladimir Vladimirovich - Dr. of Sci. (Med.), Head of the 1st Department and Clinic (for Therapy of Continuing Medical Education).</p><p>194044, Saint-Petersburg, 6, Akademika Lebedev Street</p></bio><email xlink:type="simple">vlasaluk@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кадин</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kadin</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кадин Дмитрий Владимирович – врач.</p><p>194044, Санкт-Петербург, ул. Академика Лебедева, д. 6</p></bio><bio xml:lang="en"><p>Kadin Dmitry Vladimirovich – Doctor.</p><p>194044, Saint-Petersburg, 6, Akademika Lebedev Street</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное военное образовательное учреждение высшего образования «Военно-медицинская академия имени С.М. Кирова» Министерства обороны Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Military Educational Institution of Higher Education Military Medical Academy named after S.M. Kirov of the Ministry of Defense of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>21</day><month>08</month><year>2019</year></pub-date><volume>0</volume><issue>4</issue><fpage>94</fpage><lpage>102</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Салухов В.В., Кадин Д.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Салухов В.В., Кадин Д.В.</copyright-holder><copyright-holder xml:lang="en">Salukhov V.V., Kadin D.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/3122">https://www.med-sovet.pro/jour/article/view/3122</self-uri><abstract><p>Ожирение становится все более распространенным и проявляет себя как фактор риска многих неинфекционных заболеваний. За последние десятилетия получены значительные массивы информации относительно связи ожирения с риском развития некоторых злокачественных новообразований, в особенности желудочно-кишечного тракта и женской половой системы. В данной обзорной статье обсуждаются вопросы достоверности имеющихся статистических данных, влияние типа опухоли, возрастных и гендерных особенностей на онкологический риск, освещаются традиционные и перспективные гипотезы о возможной роли ожирения в онкогенезе. В сжатом виде представлены сведения о влиянии ожирения на течение развившейся онкопатологии и о роли снижения массы тела в снижении онкологического риска.</p></abstract><trans-abstract xml:lang="en"><p>Obesity is becoming increasingly common and is becoming a risk factor for many non-communicable diseases. Over the past decades, considerable information has been gathered on the relationship between obesity and the risk of certain malignant neoplasms, particularly the gastrointestinal tract and the female genital system. This review article discusses the reliability of available statistical data, the impact of the type of tumor, age and gender peculiarities on cancer risk, highlights traditional and prospective hypotheses about the possible role of obesity in oncogenesis. The data on the influence of obesity on the course of developed oncopathology and the role of weight loss in reducing cancer risk are presented in a concise form.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>рак</kwd><kwd>онкологический риск</kwd><kwd>обсервационные исследования</kwd><kwd>Менделевский анализ</kwd><kwd>патогенез</kwd><kwd>адипоцитокины</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>cancer</kwd><kwd>oncological risk</kwd><kwd>observational studies</kwd><kwd>Mendelian analysis</kwd><kwd>pathogenesis</kwd><kwd>adipocytokines</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">NCD Risk Factor Collaboration (NCD-RisC). Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 192 million participants. 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