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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2019-16-50-58</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-3757</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Сердечная недостаточность</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Heart failure</subject></subj-group></article-categories><title-group><article-title>Хроническая сердечная недостаточность: актуальные аспекты лечения в реальной клинической практике</article-title><trans-title-group xml:lang="en"><trans-title>Chronic heart failure: actual aspects of treatment in real clinical practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1597-1876</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трухан</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Trukhan</surname><given-names>D. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трухан Дмитрий Иванович, д.м.н., доцент, профессор кафедры внутренних болезней и поликлинической терапии</p></bio><bio xml:lang="en"><p>Dmitriy I. Trukhan, Dr. of Sci. (Med.), Associate Professor, Professor of Chair for Internal Diseases and Outpatient Therapy</p></bio><email xlink:type="simple">dmitry_trukhan@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7765-2726</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Давыдов</surname><given-names>Е. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Davydov</surname><given-names>E. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Давыдов Евгений Леонардович, д.м.н., доцент кафедры пропедевтики внутренних болезней и терапии</p></bio><bio xml:lang="en"><p>Evgeniy L. Davydov, Dr. of Sci. (Med.), Associate Professor, Chair for Propaedeutics of Internal Diseases and Therapy</p></bio><email xlink:type="simple">devgenii@bk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Омский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>09</day><month>10</month><year>2019</year></pub-date><volume>0</volume><issue>16</issue><fpage>50</fpage><lpage>58</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Трухан Д.И., Давыдов Е.Л., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Трухан Д.И., Давыдов Е.Л.</copyright-holder><copyright-holder xml:lang="en">Trukhan D.I., Davydov E.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/3757">https://www.med-sovet.pro/jour/article/view/3757</self-uri><abstract><p>Актуальной проблемой здравоохранения является оптимизация лекарственной терапии у пациентов с хронической сердечной недостаточностью (ХСН).</p><p>Большое число работ, посвященных вопросам лечения ХСН, формирует точку зрения, что про лечение ХСН «все давно и хорошо известно». Однако в реальной клинической практике, особенно на этапе оказания первичной медико-санитарной помощи, в силу разных причин не учитываются возможные «подводные камни, рифы и мели», недооценка которых может создать определенные сложности и быть причиной неэффективности лечения пациентов с ХСН.</p><p>В обзорной статье рассмотрен ряд важных аспектов лечения ХСН, которые в силу разных причин недооцениваются при курации пациентов. В первую очередь это относится к антагонистам минералокортикоидных рецепторов, в частности к спиронолактону, и ингибитору If-каналов синусового узла ивабрадину.</p><p>Результаты зарубежных и российских исследований, современные рекомендации по курации пациентов с ХСН свидетельствуют, что наличие в арсенале практикующего врача препаратов спиронолактон и ивабрадин позволяет оптимизировать лекарственную терапию у пациентов с ХСН и повысить ее эффективность.</p></abstract><trans-abstract xml:lang="en"><p>An urgent public health problem is the optimization of drug therapy in patients with chronic heart failure.</p><p>A large number of works devoted to the treatment of chronic heart failure form the point of view that about the treatment of chronic heart failure «all is well known for a long time.» However, in real clinical practice, especially at the stage of primary health care, for various reasons, possible pitfalls, reefs and shallows are not taken into account, the underestimation of which can introduce certain difficulties and cause the treatment of patients with chronic heart failure to be ineffective.</p><p>The review article examined a number of important aspects of the treatment of chronic heart failure, which, for various reasons, are underestimated in the supervision of patients. First of all, this refers to antagonists of mineralocorticoid receptors, in particular to spironolactone, and an inhibitor of If - channels of the sinus node ivabradine.</p><p>The results of foreign and Russian studies, modern recommendations for the supervision of patients with chronic heart failure, indicate that the presence of spironolactone and ivabradine in the arsenal of a practical doctor allows optimizing drug therapy in patients with chronic heart failure and increasing its effectiveness.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая сердечная недостаточность</kwd><kwd>лечение</kwd><kwd>лекарственная терапия</kwd><kwd>антагонисты минералокортикоидных рецепторов</kwd><kwd>спиронолактон</kwd><kwd>ингибитор If-каналов синусового узла</kwd><kwd>ивабрадин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic heart failure</kwd><kwd>treatment</kwd><kwd>drug therapy</kwd><kwd>mineralocorticoid receptor antagonists</kwd><kwd>spironolactone</kwd><kwd>If - channel inhibitor of the sinus node</kwd><kwd>ivabradine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Демографический ежегодник России. 2013. 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