medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2015-15-40-43medsovet-381Research ArticleЗАБОЛЕВАНИЯ ГОРТАНИ И ГЛОТКИDISEASES OF THE LARYNX AND PHARYNXВыбор антибиотика при обострении тонзиллитаAntibiotic of choice for exacerbation of tonsillitisКарпищенкоС. А.KarpischenkoS. A.noemail@neicon.ruКолесниковаО. М.KolesnikovaO. M.noemail@neicon.ruНИИ хирургии и неотложной медицины; Первый Санкт-Петербургский государственный медицинский университет им. академика И.П. ПавловаРоссияResearch Institute of Surgery and Emergency Medicine; First St. Petersburg State Medical University named after academician I.P. PavlovRussian Federation2015301220150154043Copyright © Карпищенко С.А., Колесникова О.М., 20152015Карпищенко С.А., Колесникова О.М.Karpischenko S.A., Kolesnikova O.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/381

В статье проанализирован подход к выбору антибактериальной терапии в лечении тонзиллита. Традиционно эрадикацию в-гемолитического стрептококка проводят пенициллинами. Недооценка микроорганизмов, вызывающих обострение тонзиллита, может приводить к неэффективности антибактериальной терапии. Золотистый стафилококк играет немаловажную роль в рецидивировании тонзиллита. Выделение данными бактериями в-лактамаз приводит к неэффективности лечения незащищенными в-лактамными антибиотиками. Комбинация амоксициллина с клавулановой кислотой действует бактерицидно, эффективна в отношении золотистого стафилококка как возбудителя часто рецидивирующего тонзиллита.

The article analyzes an approach to the choice of antibiotic therapy in the treatment of tonsillitis. Traditionally, β-hemolytic streptococcus is eradicated with penicillins. Underestimating the role of microorganisms causing exacerbation of tonsillitis can lead to ineffective antibiotic therapy. Staphylococcus aureus plays an important role in the recurrence of tonsillitis. Unprotected β-lactam antibiotics are not effective in the treatment as these bacteria produce β-lactamase. Amoxicillin in combination with clavulanic acid has bactericidal action and is effective against Staphylococcus aureus as a pathogen of frequently recurring tonsillitis.

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The authors declare that there are no conflicts of interest present.