medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2019-16-78-85medsovet-3856Research ArticleПрактикаPracticeГиперфосфатемия при хронической болезни почекHyperphosphatemia in chronic kidney diseasehttps://orcid.org/0000-0003-2257-3224МартыновС. А.MartynovS. A.

Мартынов Сергей Андреевич, д.м.н., заведующий кабинетом экс - тракорпоральных методов лечения почечной патологии

Sergey A. Martynov, Dr. of Sci. (Med.), Head of Room for Extra - corporeal Techniques in the Treatment of Renal Pathology

smartynov@inbox.ruhttps://orcid.org/0000-0002-3433-0142ШамхаловаМ. Ш.ShamkhalovaM. Sh.

Шамхалова Минара Шамхаловна, д.м.н., заведующая отделением диабетической болезни почек и посттрансплантационной реаби - литации

Minara Sh. Shamkhalova, Dr. of Sci. (Med.), Head of Department of Diabetic Kidney Disease and Post-Transplant Rehabilitation

shamkhalova@mail.ruНациональный медицинский исследовательский центр эндокринологииРоссияNational Medical Research Center for EndocrinologyRussian Federation2019091020190167885Copyright © Мартынов С.А., Шамхалова М.Ш., 20192019Мартынов С.А., Шамхалова М.Ш.Martynov S.A., Shamkhalova M.S.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/3856

Гиперфосфатемия при почечной патологии является ключевым фактором развития минеральных и костных нарушений. Она может развиться уже при начальном снижении фильтрационной функции почек и быть предиктором формирования сосудистой кальцификации и повышения риска развития сердечно-сосудистых осложнений у пациентов с хронической болезнью почек, особенно находящихся на лечении программным гемодиализом. Применение кальций-несодержащих фосфорсвязывающих препаратов без риска развития гиперкальциемии позволяет замедлить развитие кальцификации сосудов, сократить частоту неблагоприятных кардиоваскулярных событий и снизить смертность у пациентов с хронической болезнью почек.

Hyperphosphatemia in renal pathology is a key factor for developing mineral and bone disorders. It can develop even in the early stages of renal function decline and predict the formation of vascular calcification and an increased risk for developing cardiovascular complications in patients with chronic kidney disease, especially in those, who receive program hemodialysis. The use of calcium-free phosphate-binding agents that are not associated with the risk for developing hypercalcemia can slow the development of vascular calcification, reduce the incidence of adverse cardiovascular events and mortality in patients with chronic kidney disease.

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The authors declare that there are no conflicts of interest present.