medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2019-20-52-56medsovet-4398Research ArticleАКТУАЛЬНОЕ В ОТОРИНОЛАРИНГОЛОГИИACTUAL IN OTORHINOLARYNGOLOGYМесто муколитиков в лечении острого синуситаPlace of mucolytics in the treatment of acute sinusitishttps://orcid.org/0000-0001-8483-2530КрюковА. И.KryukovA. I.

Крюков Андрей Иванович, заслуженный деятель науки РФ, д.м.н., профессор, главный внештатный специалист по оториноларингологии Департамента здравоохранения города Москвы, директор, Государственное бюджетное учреждение здравоохранения «Научно-исследовательский клинический институт оториноларингологии им. Л.И. Свержевского» Департамента здравоохранения города Москвы

117152, Россия, Москва, Загородное шоссе, д. 18А, стр. 2;  117997, Россия, Москва, ул. Островитянова, д. 1

Andrey I. Kryukov, Honored Scientist of the Russian Federation, Dr. of Sci. (Med), Professor, Chief External Expert in Otorhinolaryngology of the Moscow City Health Department, Director, State Budgetary Healthcare Institution «L.I. Sverzhevskiy Scientific Research Institute of Clinical Otorhinolaryngology» of the Department of Healthcare of Moscow

18A/2, Zagorodnoye shosse, Moscow, 117152;  1, Ostrovityanova St., Moscow, 117997

KryukovAI@zdrav.mos.ruhttps://orcid.org/0000-0002-5235-7584ТуровскийА. Б.TurovskiyA. B.

Туровский Андрей Борисович, заместитель главного врача по медицинской части

 

Andrey B. Turovskiy,  Deputy Chief Medical Officer for Treatment

18A/2, Zagorodnoye shosse, Moscow, 117152; 10, Lobnenskaya Street, Moscow,  127644

an_tur@mail.ruhttps://orcid.org/0000-0002-5159-3630КолбановаИ. Г.KolbanovaI. G.

Колбанова Инна Григорьевна, к.м.н., старший научный сотрудник научно-исследовательского отдела патологии верхних дыхательных путей и ринофациальной хирургии

 

Inna G. Kolbanova, Cand. of Sci. (Med), Senior Researcher of the Research Department of Upper Respiratory Pathology and Rhinofacial Surgery

18A/2, Zagorodnoye shosse, Moscow, 117152

kolbines@yandex.ruhttps://orcid.org/0000-0003-2761-0717МусаевК. М.MusayevK. M.

Мусаев Камран Мазахир-оглы, аспирант отдела патологии верхних дыхательных путей и ринофациальной эстетической хирургии

 

Kamran M. Musayev, Postgraduate Student of the Department of Upper Respiratory Tract Pathology and Rhinofacial Aesthetic Surgery

18A/2, Zagorodnoye shosse, Moscow, 117152

qenius.m@gmail.comhttps://orcid.org/0000-0003-4311-4203КарасовА. Б.KarasovA. B.

Карасов Альберт Баймурзович, аспирант отдела патологии верхних дыхательных путей и ринофациальной эстетической хирургии

117152, Россия, Москва, Загородное шоссе, д. 18А, стр. 2

Al’bert B. Karasov, Postgraduate Student of the Department of Upper Respiratory Tract Pathology and Rhinofacial Aesthetic Surgery

18A/2, Zagorodnoye shosse, Moscow, 117152

karasov.albert@inbox.ruhttps://orcid.org/0000-0003-3960-1893ДанилюкЛ. И.DanilyukL. I.

Данилюк Леокадия Игоревна, ординатор отдела патологии верхних дыхательных путей и ринофациальной эстетической хирургии

117152, Россия, Москва, Загородное шоссе, д. 18А, стр. 2

Leokadiya I. Danilyuk, Resident of the Department of Upper Respiratory Tract Pathology and Rhinofacial Aesthetic Surgery

18A/2, Zagorodnoye shosse, Moscow, 117152

likusya2007@bk.ruНаучно-исследовательский клинический институт оториноларингологии им. Л.И. Свержевского; Российский национальный исследовательский медицинский университет им. Н.И. ПироговаРоссияL.I. Sverzhevskiy Scientific Research Institute of Clinical Otorhinolaryngology; N.I. Pirogov Russian National Research Medical UniversityRussian FederationНаучно-исследовательский клинический институт оториноларингологии им. Л.И. Свержевского; Государственное бюджетное учреждение здравоохранения города Москвы «Городская клиническая больница им. В.В. Вересаева Департамента здравоохранения города Москвы»РоссияL.I. Sverzhevskiy Scientific Research Institute of Clinical Otorhinolaryngology; City Clinical Hospital named after V.V. VeresaevRussian FederationНаучно-исследовательский клинический институт оториноларингологии им. Л.И. СвержевскогоРоссияL.I. Sverzhevskiy Scientific Research Institute of Clinical OtorhinolaryngologyRussian Federation2019161120190205256Copyright © Крюков А.И., Туровский А.Б., Колбанова И.Г., Мусаев К.М., Карасов А.Б., Данилюк Л.И., 20192019Крюков А.И., Туровский А.Б., Колбанова И.Г., Мусаев К.М., Карасов А.Б., Данилюк Л.И.Kryukov A.I., Turovskiy A.B., Kolbanova I.G., Musayev K.M., Karasov A.B., Danilyuk L.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/4398

Цель работы – анализ современных представлений о местных изменениях слизистой оболочки ОНП при ОС, а также о методах фармакотерапии этого заболевания. Авторами рассмотрены основные механизмы патогенеза как острого, так и хронического синусита. Подробно описана одна из причин, лежащая в основе развития инфекционного воспаления: нарушение дренажной функции околоносовых пазух, аэрации, мукоцилиарного транспорта. Произведена аналитическая оценка современных средств рациональной фармакотерапии. Сделан вывод, что использование муколитических препаратов улучшает результаты лечения.

Aim of the study - the analysis of the current understanding of local changes in the mucous membrane of PNS in AS, as well as methods of pharmacotherapy of the disease. The authors consider the main mechanisms of pathogenesis of both acute and chronic sinusitis. One of the reasons underlying the development of infectious inflammation is described in detail: disturbance of drainage function of paranasal sinuses, aeration, mucociliary transport. Analytical evaluation of modern means of rational pharmacotherapy was made. It is concluded that the use of mucolytic drugs improves treatment results.

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The authors declare that there are no conflicts of interest present.