medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2015-18-6-10medsovet-444Research ArticleЦЕРЕБРОВАСКУЛЯРНЫЕ ЗАБОЛЕВАНИЯCEREBROVASCULAR DISEASESЦитиколин при ишемическом инсульте: от острого периода к реабилитацииCiticoline for ischemic stroke: from acute phase to rehabilitationСергеевД. В.SergeevD. V.noemail@neicon.ruДомашенкоМ. А.DomashenkoM. A.noemail@neicon.ruПирадовМ. А.PiradovM. A.noemail@neicon.ruНаучный центр неврологииРоссияResearch Center of NeurologyRussian Federation201530122015018610Copyright © Сергеев Д.В., Домашенко М.А., Пирадов М.А., 20152015Сергеев Д.В., Домашенко М.А., Пирадов М.А.Sergeev D.V., Domashenko M.A., Piradov M.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/444

Применение эффективной патогенетической терапии ишемического инсульта - реперфузионных вмешательств - существенно ограничено необходимостью тщательного отбора пациентов и организации службы специализированной помощи. В связи с этим особое значение приобретают фармакологические методы лечения, направленные на поддержание жизнеспособности нейронов в зоне ишемии. К наиболее изученным и перспективным нейропротекторам относится цитиколин. Препарат улучшает исход у отдельных групп пациентов с острым ишемическим инсультом, а также оказывает благоприятный эффект в отношении когнитивных функций в восстановительном периоде. Кроме того, существуют свидетельства эффективности препарата в отношении восстановления функции верхней конечности у пациентов с гемиплегией. Цитиколин можно рекомендовать как в остром периоде ишемического инсульта, так и на этапе реабилитации.

Effective pathogenetic therapy of ischemic stroke - reperfusion intervention - is largely restricted by mandatory careful selection of patients and availability of specialized care. Pharmacological treatments are therefore becoming especially relevant as they are aimed at maintaining viability of neurons in the ischemic area. The most studied and promising neuroprotectives are citicolines. They improve outcomes in individual groups of patients with acute ischemic stroke, and have beneficial effects on cognitive function in the recovery period. The drug also proved to be effective in the recovery of upper limb function in patients with hemiplegia. Citicoline can be recommended both for acute ischemic stroke and at the rehabilitation stage.

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The authors declare that there are no conflicts of interest present.