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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2019-20-115-120</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-4508</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДИССЕРТАНТ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DISSERTANT</subject></subj-group></article-categories><title-group><article-title>Роль гомеостатических нарушений в развитии генерализованных воспалительных заболеваний пародонта у больных большой β-талассемией</article-title><trans-title-group xml:lang="en"><trans-title>The role of homeostatic disorders in development of periodontal generalized inflammatory diseases in patients with β-thalassemya major</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8296-1280</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шадлинская</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shadlinskaya</surname><given-names>R. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шадлинская Рамида Вагиф-кызы, доцент кафедры детской стоматологии, стоматологическая клиника</p><p>AZ1078, Азербайджан, Баку, ул. Самеда Вургуна, д. 175 </p></bio><bio xml:lang="en"><p>Ramida Vaqif Shadlinskaya, Associate Professor, Chair for Pediatric Dentistry, Dental Clinic</p><p>175, S. Vurgun st., Baku, AZЕ1078</p></bio><email xlink:type="simple">r.shadlinskaya@yahoo.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Азербайджанский медицинский университет<country>Азербайджан</country></aff><aff xml:lang="en">Azerbaijan Medical University<country>Azerbaijan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>16</day><month>11</month><year>2019</year></pub-date><volume>0</volume><issue>20</issue><fpage>115</fpage><lpage>120</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шадлинская Р.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Шадлинская Р.В.</copyright-holder><copyright-holder xml:lang="en">Shadlinskaya R.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/4508">https://www.med-sovet.pro/jour/article/view/4508</self-uri><abstract><p>Пародонтальный синдром как элемент симптомокомплекса системных заболеваний в современной классификации заболеваний пародонта выделен в отдельную группу и имеет собственные отличительные черты, обусловленные особенностями системной патологии. Влияние на состояние тканей пародонта при большой β-талассемии, особенно в старших возрастных группах, можно расценивать как формирование пародонтального синдрома, обусловленного как опосредованным влиянием через формирование травмирующей патологии прикуса, так и непосредственным включением в классическую модель иммунопатогенеза воспалительных заболеваний пародонта, степень выраженности которых зависит от уровня компенсации системной патологии.</p></abstract><trans-abstract xml:lang="en"><p>Periodontitis as a manifestation of the systemic diseases was placed in separated part in the contemporary periodontal diseases classification. It has its own specific traits caused by features of the common pathology. The way as ß-thalassemia major is impacting to periodontium could be recognized as the indirect acting out of the side of dental and occlusal anomalies or direct acting of ß-thalassemia major to the periodontium. The range of the influence on periodontium depends on the degree of intensity of the systemic diseases.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>талассемия</kwd><kwd>воспалительные заболевания пародонта</kwd><kwd>гомеостатические нарушения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>thalassemia</kwd><kwd>periodontal diseases</kwd><kwd>homeostatic disorders</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Орехова Л.Ю., Кирсанов А.И., Горбачева И.А. Перекисное окисление липидов у больных генерализованным пародонтитом в сочетании с хроническими заболеваниями внутренних органов. Актуальные проблемы экспериментальной и клинической фармакологии: материалы Всероссийской научной конференции. СПб., 2–5 июня, 1999: 197–198.</mixed-citation><mixed-citation xml:lang="en">Orekhova L.Yu., Kirsanov A.I., Gorbacheva I.A. 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