medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2019-17-17-23medsovet-4541Research ArticleНЕОНАТОЛОГИЯNEONATOLOGYНовые возможности для сохранения грудного вскармливания за счет применения пробиотиков для профилактики мастита и лактостаза у кормящих женщинNew trends in preserving breastfeeding by use of probiotics to prevent mastitis and lactostasis in breastfeeding womenhttps://orcid.org/0000-0003-4200-4598ЗахароваИ. Н.ZakharovaI. N.

Захарова Ирина Николаевна, доктор медицинских наук, профессор, заслуженный врач России, заведующая кафедрой педиатрии с курсом поликлинической педиатрии им. Г.Н. Сперанского

125993, Москва, ул. Баррикадная, д. 2/1, стр. 1

Irina N. Zakharova, Dr. of Sci. (Med.), Professor, Honoured Doctor of Russia, Head of Speranskiy Chair for Paediatrics with Outpatient Pediatrics Module

Bldg. 1, 2/1 Barrikadnaya St., Moscow, 125993

kafedra25@yandex.ruКучинаА. Е.KuchinaА. Е.

Кучина Анастасия Евгеньевна, врач-педиатр, аспирант кафедры педиатрии с курсом поликлинической педиатрии им. Г.Н. Сперанского

125993, Москва, ул. Баррикадная, д. 2/1, стр. 1

Anastasiya E. Kuchina, Paediatrician, Post-Graduate Student of Speranskiy Chair for Paediatrics with Outpatient Pediatrics Module

Bldg. 1, 2/1 Barrikadnaya St., Moscow, 125993

kafedra25@yandex.ruБережнаяИ. В.BerezhnayaI. V.

Бережная Ирина Владимировна, кандидат медицинских наук, доцент кафедры педиатрии с курсом поликлинической педиатрии им. Г.Н. Сперанского

125993, Москва, ул. Баррикадная, д. 2/1, стр. 1

Irina V. Berezhnaya, Cand. of Sci. (Med.), Associate Professor, Speranskiy Chair for Paediatrics with Outpatient Pediatrics Module

Bldg. 1, 2/1 Barrikadnaya St., Moscow, 125993

 

berezhnaya-irina26@yandex.ruРоссийская медицинская академия непрерывного профессионального образованияРоссияRussian Medical Academy of Continuing Postgraduate EducationRussian Federation2019231120190171723Copyright © Захарова И.Н., Кучина А.Е., Бережная И.В., 20192019Захарова И.Н., Кучина А.Е., Бережная И.В.Zakharova I.N., Kuchina А.Е., Berezhnaya I.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/4541

В статье обсуждается уникальное свойство автономной изменчивости состава грудного молока под воздействием внешних факторов, в т. ч. под влиянием эндогенных (гормональных) и экзогенных (диетических, экологических) факторов. Представлен анализ результатов исследований, каким образом влияют способ родоразрешения и антибиотикопрофилактика на бактериальный состав молока, а также обсуждается вопрос, есть ли разница между этими двумя факторами. Приводятся результаты исследований EUROMAPGROUP и HUMAP и ориентировочный подсчет объема антибиотиков (в тоннах), применяемых в животноводстве, что демонстрирует одну из гло бальных проблем современности – антибиотикорезистентность. С целью предотвращения получения ребенком субтерапевтических доз антибиотика с молоком матери предложен современный способ профилактики лактационного мастита с помощью пробиотика Lactobacillus fermentum CECT5716, недавно появившегося на российском фармацевтическом рынке. Приведены основные исследования, посвященные пробиотикам грудного молока и профилактике мастита и лактостаза у кормящих женщин.

The article discusses the unique property of autonomous variability in breast milk composition under the influence of external factors, including endogenous (hormonal) and exogenous (dietary, environmental) factors. The authors presented the analysis of study findings, how the method of delivery and antibiotic prophylaxis affect the bacterial composition of milk and discuss whether there is a difference between two factors. The results of EUROMAPGROUP and HUMAP studies and an approximate estimation of antibiotics volume (in tons) used in food animal production are presented, which demonstrates one of the global problems of our time antibiotic resistance. A modern method for preventing lactational mastitis using the probiotic Lactobacillus fermentum CECT5716, which was recently launched to the Russian pharmaceutical market, is proposed to prevent the child from receiving subtherapeutic antibiotic doses with mother’s milk. The main studies on the breast milk probiotics and the prevention of mastitis and lactostasis in breastfeeding women are presented.

грудное молокогрудное вскармливаниеантибиотикопрофилактикамикробиота грудного молокапробиотикимаститлактостазкормящая женщинадетикесарево сечениеантибиотикипрофилактикаантибиотикорезистентностьL. fermentumL. salivariusbreast milkbreastfeedingantibiotic prophylaxisbreast milk microbiotaprobioticsmastitislactostasisbreastfeeding womanchildrencesarean sectionantibioticspreventionantibiotic resistanceL. fermentumL. salivariusReferencesVictora C.G., Bahl R., Barros A.J., Victora C.G., Bahl R., Barros A.J., Franca G.V., Horton S., Krasevec J., Murch S., Sankar M.J., Walker N., Rollins N.C. Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect. Lancet. 2016;387(10017):475–490. doi: 10.1016/S0140-6736(15)01024-7.Victora C.G., Bahl R., Barros A.J., Victora C.G., Bahl R., Barros A.J., Franca G.V., Horton S., Krasevec J., Murch S., Sankar M.J., Walker N., Rollins N.C. Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect. 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The authors declare that there are no conflicts of interest present.