medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2019-17-147-155medsovet-4717Research ArticleГАСТРОЭНТЕРОЛОГИЯGASTROENTEROLOGYМладенческая колика с позиций доказательной медицины: распространенность, принципы дифференциальной диагностики, алгоритм выбора диетотерапииInfantile colic from the perspective of evidence-based medicine: prevalence, principles of differential diagnosis and diet therapy algorithmhttps://orcid.org/0000-0002-2666-4759ГуроваМ. М.GurovaМ. М.

Гурова Маргарита Михайловна, доктор медицинских наук, профессор, ведущий научный сотрудник, лаборатория медико-социальных проблем в педиатрии, Федеральное государственное бюджетное образовательное учреждение высшего образования «Санкт-Петербургский государственный педиатрический медицинский университет» Министерства здравоохранения Российской Федерации; кафедра педиатрии с курсом детской хирургии, Федеральное государственное автономное образовательное учреждение высшего образования «Белгородский государственный национальный исследовательский университет»; заведующая отделением абдоминальной патологии с эндоскопией и функциональной диагностикой, Санкт-Петербургское государственное бюджетное учреждение здравоохранения «Консультативно-диагностический центр для детей»

194100, Санкт-Петербург, ул. Литовская, д. 2;

308015, Белгород, ул. Победы, д. 85,

192289, Санкт-Петербург, ул. Олеко Дундича, д. 36, корп. 2

Margarita M. Gurova, Dr. of Sci. (Med.), Professor, Senior Researcher, Laboratory of Medical and Social Problems in Pediatrics, Federal State Budgetary Educational Institution of Higher Education «St. Petersburg State Pediatric Medical University» of the Ministry of Health of the Russian Federation; Chair for Pediatrics with Pediatric Surgery Module, Federal State Autonomous Educational Institution of Higher Education «Belgorod State University»; Head of Department of Abdominal Pathology with Endoscopy and Functional Diagnostics, St. Petersburg State Budgetary Healthcare Institution «Consultative and Diagnostic Center for Children»

2, Litovskaya St., St. Petersburg, 194100,

85, Pobedy St., Belgorod, 308015,

Bldg. 2, 36, Oleko Dundicha St., Saint Petersburg, 192289

itely@mail.ruСанкт-Петербургский государственный педиатрический медицинский университет; Белгородский государственный национальный исследовательский университет; Консультативно-диагностический центр для детейРоссияSt. Petersburg State Pediatric Medical University; Russia Belgorod State University; Clinical diagnostic center for childrenRussian Federation201924112019017147155Copyright © Гурова М.М., 20192019Гурова М.М.Gurova М.М.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/4717

В статье представлены данные по распространенности младенческой колики, этиологическим факторам, критериям диагностики, дифференциальной диагностики и терапии с обоснованием подходов к выбору смесей у детей, находящихся на искусственном вскармливании. При выборе смеси необходимо учитывать особенности состава, направленные на преодоление функциональной незрелости желудочно-кишечного тракта, энтеральной нервной системы, продолжающееся формирование микробиома кишечника – наличие частично-гидролизованного белка, сниженное содержание лактозы, наличие пребиотиков (фруктоолигосахариды) и пробиотиков. Смесь Similac Комфорт полностью соответствует предъявляемым требованиям. Смесь содержит олигосахарид грудного молока 2-фукозиллактозу (2’-FL) 0,2 г/л – полностью идентичный содержащемуся в грудном молоке, имеющий доказанные положительные эффекты в виде иммуномодулирующего действия, противоинфекционного эффекта за счет антиадгезивного действия, участвует в регуляции роста и созревании эпителиальных клеток кишечника, в развитии нервной системы.

The article presents data on the prevalence of infant colic, etiological factors, diagnostic criteria, differential diagnosis and therapy with justification of approaches to the choice of formula in children on artificial feeding. When choosing a formula, it is necessary to take into account the compositional features aimed at overcoming the functional immaturity of the gastrointestinal tract, enteric nervous system, and the ongoing formation of the intestinal microbiome – the presence of a partially hydrolyzed protein, a reduced lactose content, the presence of prebiotics (fructooligosaccharides) and probiotics. The formula Similac Comfort is fully compliant. This formula additionally contains oligosaccharide of the breast milk 2 fucosillactose (2’-FL), 0.2 g / l – identical to that found in breast milk, which has proven positive effects in the form of an immunomodulating effect, anti-infectious effect, is involved in the regulation of growth and maturation of intestinal epithelial cells, in the development of the nervous system.

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The authors declare that there are no conflicts of interest present.