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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2015-XX-64-67</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-475</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Инфекции в акушерстве и гинекологии</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Infections in obstetrics and gynecology</subject></subj-group></article-categories><title-group><article-title>Патогенетическая терапия бактериального вагиноза - приоритеты и акценты</article-title><trans-title-group xml:lang="en"><trans-title>Pathogenetic therapy of bacterial vaginosis - priorities and focus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Озолиня</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ozolinya</surname><given-names>L. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бондаренко</surname><given-names>К. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Bondarenko</surname><given-names>K. R.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лапина</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lapina</surname><given-names>I. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н.И. Пирогова Минздрава России, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2015</year></pub-date><volume>0</volume><issue>XX</issue><fpage>64</fpage><lpage>67</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Озолиня Л.А., Бондаренко К.Р., Лапина И.А., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Озолиня Л.А., Бондаренко К.Р., Лапина И.А.</copyright-holder><copyright-holder xml:lang="en">Ozolinya L.A., Bondarenko K.R., Lapina I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/475">https://www.med-sovet.pro/jour/article/view/475</self-uri><abstract><p>Нарушения влагалищного микробиоценоза проявляются различными заболеваниями и клиническими синдромами. При этом чаще всего дисбаланс микрофлоры влагалища манифестирует в виде бактериального вагиноза (БВ), патогенетически обусловленного вытеснением вагинальных лактобацилл условно-патогенными облигатными анаэробами. Основной проблемой, с которой сталкиваются врачи-клиницисты при лечении БВ, считается его склонность к частому рецидивированию. Так, по некоторым данным, у 30% пролеченных женщин рецидив БВ в среднем регистрируется в течение 3 мес., у 50% -в течение 6 мес. соответственно [<xref ref-type="bibr" rid="cit1">1</xref>]. Но в связи с тем, что до настоящего времени не удалось установить этиологию указанного синдрома, унифицированная терапевтическая стратегия при рецидивах БВ не разработана и не включена в отечественные и зарубежные клинические рекомендации.</p></abstract><trans-abstract xml:lang="en"><p>Impaired vaginal microbiocenosis results in various diseases and clinical syndromes. Vaginal microflora imbalance is most often manifested in the form of bacterial vaginosis (BV) caused by the displacement of vaginal lactobacilli with pathogenic obligate anaerobes. The major problem faced by clinicians in the treatment of BV is its tendency towards frequent recurrence. Thus, according to some sources, in 30% of women recurring BV is registered on average within three months after treatment, in 50% - within six months, respectively [<xref ref-type="bibr" rid="cit1">1</xref>]. However, as the etiology of the syndrome has not been established so far, there is not a unified therapeutic strategy for recurrent BV, neither is it included in any local and global clinical guidelines.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>влагалищный микробиоценоз</kwd><kwd>бактериальный вагиноз</kwd><kwd>лактобациллы pH вагинальной среды</kwd><kwd>L-аскорбиновая кислота</kwd><kwd>vaginal microbiocaenosis</kwd><kwd>bacterial vaginosis</kwd><kwd>lactobacilli</kwd><kwd>vaginal pH</kwd><kwd>L-ascorbic acid</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bradshaw C.S., Tabrizi S.N., Fairley C.K. et al. The association of Ato-pobium vaginae and Gardnerella vaginalis with bacterial vaginosis and recurrence after oral metronidazole therapy // J. Infect. 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