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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2016-2-100-101</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-49</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДИССЕРТАНТ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DISSERTANT</subject></subj-group></article-categories><title-group><article-title>Клиническое значение естественного аутоиммунитета у пациенток со спаечным процессом и наружным генитальным эндометриозом</article-title><trans-title-group xml:lang="en"><trans-title>The clinical significance of natural autoimmunity in patients with adhesive process and external genital endometriosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каракашян</surname><given-names>Н. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Karakashian</surname><given-names>N. R.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Манухина</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Manukhina</surname><given-names>E. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Геворкян</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gevorgyan</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Манухин</surname><given-names>И. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Manukhin</surname><given-names>I. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Московский государственный медико-стоматологический университет им. А.И. Евдокимова<country>Россия</country></aff><aff xml:lang="en">First Moscow State University of Medicine and Dentistry named after A.I. Evdokimov<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2016</year></pub-date><volume>0</volume><issue>2</issue><fpage>100</fpage><lpage>101</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Каракашян Н.Р., Манухина Е.И., Геворкян М.А., Манухин И.Б., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Каракашян Н.Р., Манухина Е.И., Геворкян М.А., Манухин И.Б.</copyright-holder><copyright-holder xml:lang="en">Karakashian N.R., Manukhina E.I., Gevorgyan M.A., Manukhin I.B.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/49">https://www.med-sovet.pro/jour/article/view/49</self-uri><abstract><p>В статье представлены результаты исследований 71 пациентки со спаечным процессом и лапаро-скопически подтвержденным диагнозом «наружный генитальный эндометриоз» (НГЭ). В соответствии с оценкой специфической сывороточной иммунореактивности все пациентки были разделены на 3 группы: группа А (нормореактивный тип), группа В (гиперреактивный тип) и группа С (гипоре-активный тип). Длительность бесплодия - в среднем 6,1 ± 1,3 года. После хирургического лечения проводилась антигонадотропная терапия: бусерелин 3,75 мг (курсом 4-6 инъекций). Всем больным групп В и С на фоне основной терапии проводилась коррекция иммунологических нарушений. Вывод: коррекция иммунологических нарушений у больных со спаечным процессом, ассоциированным с НГЭ, способствует повышению эффективности восстановления репродуктивной функции.</p></abstract><trans-abstract xml:lang="en"><p>The article presents the results of a study of 71 patients with adhesive process diagnosed with external genital endometriosis (EGE) confirmed by laparoscopy. In accordance with the specific serum immunoreactivity evaluation, all patients were divided into 3 groups: Group A (normal response type), Group B (hyper-response type) and group C (hypo-response type). The duration of infertility was on average 6,1 ± 1,3 years. After surgery patients underwent antigonadotropic therapy with 3.75 mg buserelin (a course of 4--6 injections). Against a background of the baseline therapy, all patients in groups B and C underwent correction of immunological disorders. Conclusion: Management of immunological disorders in patients with adhesive process associated with EGE enhances the effectiveness of recovery of the reproductive function</p></trans-abstract><kwd-group xml:lang="ru"><kwd>наружный генитальный эндометриоз</kwd><kwd>бесплодие</kwd><kwd>спаечный процесс</kwd><kwd>иммунореактивность</kwd><kwd>external genital endometriosis</kwd><kwd>infertility</kwd><kwd>adhesive process</kwd><kwd>immunoreactivity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Краснопольская К.В., Штыров С.В., Мачанските О.В., Чеченова Ф.К. Исходы реконструктивно-пластических операций при трубно-перито-неальной форме бесплодия. Проблемы репродукции. 2001, 3: 12-5.</mixed-citation><mixed-citation xml:lang="en">Краснопольская К.В., Штыров С.В., Мачанските О.В., Чеченова Ф.К. 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