medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2019-18-119-126medsovet-5014Research ArticleПрактикаPracticeБоль в спине и остеопороз позвоночника в клинической практикеBack pain and spinal osteoporosis in clinical practiceПизоваН. В.PizovaN. V.

Пизова Наталия Вячеславовна, д.м.н., профессор, кафедра нервных болезней с медицинской генетикой и нейрохирургией

150000,  Ярославль, ул. Революционная, д. 5

Nataliya V. Pizova, Dr. of Sci. (Med), Professor, Department of Nervous Diseases with Medical Genetics and Neurosurgery

5, Revolutsionnaya St., Yaroslavl, 150000

pizova@yandex.ruПизовА. В.PizovA. V.

Пизов Александр Витальевич, к.б.н., доцент кафедры методики преподавания естественно-математических дисциплин

150000, Ярославль, ул. Республиканская, д. 108/1

Aleksandr V. Pizov, Cand. of Sci. (Bio), Associate Professor

108/1, Respublikanskaya St., Yaroslavl, 150000

Ярославский государственный медицинский университетРоссияFederal State Budgetary Educational Institution of Higher Education «Yaroslavl State Medical University» of the Ministry of Health of the Russian FederationRussian FederationЯрославский государственный педагогический университет им. К.Д. УшинскогоРоссияFederal State Budgetary Educational Institution of Higher Education «Yaroslavl State Medical University» of the Ministry of Health of the Russian FederationRussian Federation201901122019018119126Copyright © Пизова Н.В., Пизов А.В., 20192019Пизова Н.В., Пизов А.В.Pizova N.V., Pizov A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/5014

Боль в спине является распространенной клинической и значительной социально-экономической проблемой. Боль в спине – симптом, а не нозологическая форма. Остеопороз – болезнь скелета, при которой, несмотря на нормальную минерализацию костной ткани, наблюдается снижение костной массы и нарушение целостности (структуры) костной ткани. В статье рассмотрены основные причины первичного и вторичного остеопороза. Представлены основные модифицируемые и немодифицируемые факторы риска возникновения остеопороза и переломов. Описаны основные патологические состояния и заболевания, ассоциированные с риском развития остеопороза. Углубленно рассмотрена проблема остеопороза позвоночника как одна из причин механических болевых эпизодов в спине у пожилых пациентов. Представлены клинические особенности компрессионных переломов позвонков при остеопорозе у женщин после наступления менопаузы. Рассмотрены методы консервативного лечения остеопороза. Наибольшее внимание уделено таким эффективным антиостеопоротическим препаратам, как бисфосфонаты. Проанализированы данные об эффективности и переносимости препаратов алендроновой кислоты как наиболее изученного препарата из группы бисфосфонатов. Представлена информация о новой лекарственной форме алендроновой кислоты – шипучих растворимых таблетках (Биносто).

Back pain is a common clinical and socioeconomic problem. Back pain is a symptom, not a nosological form. Osteoporosis is a skeletal disease in which, despite normal bone mineralization, bone loss and bone (structure) integrity is observed. The article considers the main causes of primary and secondary osteoporosis. The main modifiable and unmodifiable risk factors for osteoporosis and fractures are presented. The main pathological conditions and diseases associated with the risk of osteoporosis are described. The problem of osteoporosis of the spine as one of the causes of mechanical painful episodes in the back of elderly patients is considered in depth. Clinical features of compression vertebral fractures in osteoporosis in women after menopause are presented. The methods of conservative treatment of osteoporosis are considered. The greatest attention is paid to such effective antiosteoporotic drugs as bisphosphonates. The data on the efficacy and tolerability of alendronic acid preparations as the most studied preparation from the group of bisphosphonates are analyzed. The information on the new medicinal form of alendronic acid – sparkling soluble tablets (Binosto) is presented.

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The authors declare that there are no conflicts of interest present.