medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2014-2-18-25medsovet-502Research ArticleКАРДИОЛОГИЯCARDIOLOGYВозможности коррекции гиперурикемии при метаболическом синдромеCorrection of hyperuricemia in metabolic syndromeНедогодаС. В.NedogodaS. V.noemail@neicon.ruСаласюкА. С.SalasyukA. S.noemail@neicon.ruБарыкинаИ. Н.BarykinaI. N.noemail@neicon.ruЛедяеваА. А.LedyaevaA. A.noemail@neicon.ruЦомаВ. В.TsomaV. V.noemail@neicon.ruЧумачекЕ. В.ChumachekE. V.noemail@neicon.ruХрипаеваВ. Ю.KhripaevaV. Y.noemail@neicon.ruВолгоградский государственный медицинский университетРоссияVolgograd State Medical UniversityRussian Federation201430122014021825Copyright © Недогода С.В., Саласюк А.С., Барыкина И.Н., Ледяева А.А., Цома В.В., Чумачек Е.В., Хрипаева В.Ю., 20142014Недогода С.В., Саласюк А.С., Барыкина И.Н., Ледяева А.А., Цома В.В., Чумачек Е.В., Хрипаева В.Ю.Nedogoda S.V., Salasyuk A.S., Barykina I.N., Ledyaeva A.A., Tsoma V.V., Chumachek E.V., Khripaeva V.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/502

Метаболический синдром (МС) имеет многогранный патогенез, в большинстве механизмов которого так или иначе участвует мочевая кислота. Активную роль избыток уратов играет в процессе воспаления, эндотелиальной дисфункции, атерогенезе, инсулинорезистентности. Нацеленность на выявление гиперурикемии является инструментом успешного контроля сердечно-сосудистого риска. Выбор антигипертензивных и гиполипидемических препаратов при МС должен определяться их способностью контролировать уровень мочевой кислоты сыворотки крови.

Metabolic syndrome (MS) is a complex pathogenic condition, many mechanisms of which involve uric acid. Inflammation, endothelial dysfunction, atherogenesis and insulin resistance are largely determined by high level of uric acid. Focus on the identification of hyperuricemia is the prerequisite for successful management of cardiovascular risk. The choice of antihypertensive and lipid-lowering drugs in MS should be determined by their ability to control the level of serum uric acid.

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The authors declare that there are no conflicts of interest present.