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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2019-19-44-49</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-5135</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТАРГЕТНАЯ ТЕРАПИЯ ОПУХОЛЕЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Target therapy of tumors</subject></subj-group></article-categories><title-group><article-title>Постнеоадъювантная терапия – новый подход в лечении HER2-положительного рака молочной железы (результаты исследования KATHERINE)</article-title><trans-title-group xml:lang="en"><trans-title>Postneoadjuvant therapy: a new approach to the treatment of HER2-positive breast cancer (KATHERINE study results)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4848-6938</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жукова</surname><given-names>Л. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhukova</surname><given-names>L. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор РАН, заместитель директора по онкологии</p><p>111123, Россия, Москва, шоссе Энтузиастов, д. 86 </p></bio><bio xml:lang="en"><p>Dr. of Sci. (Med.), Professor of RAS, Deputy Oncology Director</p><p>86 Shosse Entuziastov, Moscow, 111123, Russia </p></bio><email xlink:type="simple">l.zhukova@mknc.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8887-2660</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смолин</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Smolin</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>младший научный сотрудник отделения химиотерапии </p><p>111123, Россия, Москва, шоссе Энтузиастов, д. 86 </p></bio><bio xml:lang="en"><p>Junior Researcher, Chemotherapy Department</p><p>86 Shosse Entuziastov, Moscow, 111123, Russia </p></bio><email xlink:type="simple">hsifdaeh@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский клинический научно-практический центр имени А.С. Логинова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Budgetary Health Institution of the city of Moscow «Loginov Moscow Clinical Research Center» of Moscow Health Department</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>05</day><month>12</month><year>2019</year></pub-date><volume>0</volume><issue>19</issue><fpage>44</fpage><lpage>50</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Жукова Л.Г., Смолин С.А., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Жукова Л.Г., Смолин С.А.</copyright-holder><copyright-holder xml:lang="en">Zhukova L.G., Smolin S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/5135">https://www.med-sovet.pro/jour/article/view/5135</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>HER2-позитивный РМЖ</kwd><kwd>адъювантная терапия</kwd><kwd>трастузумаб эмтанзин</kwd><kwd>T-DM1</kwd><kwd>KATHERINE</kwd><kwd>iDFS</kwd><kwd>остаточная опухоль</kwd></kwd-group><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>HER2-positive breast cancer</kwd><kwd>adjuvant therapy</kwd><kwd>trastuzumab emtansine</kwd><kwd>T-DM1</kwd><kwd>KATHERINE</kwd><kwd>iDFS</kwd><kwd>residual tumor</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Susmitha Apuri. 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