medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2019-19-51-56medsovet-5146Research ArticleТАРГЕТНАЯ ТЕРАПИЯ ОПУХОЛЕЙTarget therapy of tumorsРациональный подход к терапии EGFR-позитивного рака легкогоRational approach to the treatment of EGFR-positive lung cancerhttps://orcid.org/0000-0002-2154-3376РеутоваЕ. В.ReutovaE. V.

к.м.н., старший научный сотрудник

115478, Россия, Москва, Каширское шоссе, д. 23

Cand. of Sci. (Med), Senior Researcher

23, Kashirskoye sh., Moscow, 115478, Russia

evreutova@rambler.ruhttps://orcid.org/0000-0003-4469-502XЛактионовК. К.LaktionovK. K.

д.м.н., профессор, заведующий отделением химиотерапии №1 торако-абдоминального отдела

115478, Россия, Москва, Каширское шоссе, д. 23 

Dr. of Sci. (Med), Professor, Head of the Department of Chemotherapy No.1 of the Thoraco-Abdominal Department

23, Kashirskoye sh., Moscow, 115478, Russia

lkoskos@mail.ruhttps://orcid.org/0000-0002-0620-2696ЮдинД. И.YudinD. I.

к.м.н., старший научный сотрудник

115478, Россия, Москва, Каширское шоссе, д. 23 

Cand. of Sci. (Med), Senior Researcher

23, Kashirskoye sh., Moscow, 115478, Russia

yudinden@mail.ruАрдзинбаМ. С.ArdzinbaM. S.

к.м.н., врач-онколог, онкологическое отделение лекарственных методов лечения №17 (химиотерапевтическое)

115478, Россия, Москва, Каширское шоссе, д. 23 

Cand. of Sci. (Med), Oncologist, Oncological Department of Medicinal Methods of Treatment No. 17 (chemotherapeutic)

23, Kashirskoye sh., Moscow, 115478, Russia

merabii@mail.ruНациональный медицинский исследовательский центр онкологии имени Н.Н. БлохинаРоссияFederal State Budgetary Institution «N.N. Blokhin Russian Cancer Research Center» of the Ministry of Health of the Russian FederationRussian Federation2019051220190195156Copyright © Реутова Е.В., Лактионов К.К., Юдин Д.И., Ардзинба М.С., 20192019Реутова Е.В., Лактионов К.К., Юдин Д.И., Ардзинба М.С.Reutova E.V., Laktionov K.K., Yudin D.I., Ardzinba M.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/5146немелкоклеточный рак легкогоприобретенная резистентностьмутации EGFRингибиторы тирозинкиназы EGFRT790MDel19L858Rnon-small-cell lung canceracquired resistanceEGFR mutationsEGFR tyrosine kinase inhibitorsT790MDel19L858RReferencesTjulandin S., Imyanitov E., Moiseyenko V., Ponomarenko D., Gurina L., Koroleva I., Karaseva V. 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The authors declare that there are no conflicts of interest present.