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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2019-19-132-136</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-5298</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКОЕ НАБЛЮДЕНИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATION</subject></subj-group></article-categories><title-group><article-title>Иммунотерапия рецидивного немелкоклеточного рака легкого в первой линии</article-title><trans-title-group xml:lang="en"><trans-title>Immunotherapy in first-line treatment of recurrent non-small cell lung cancer</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4980-8986</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Родионов</surname><given-names>Е. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Rodionov</surname><given-names>E. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p> к.м.н., старший научный сотрудник отделения торакальной онкологии; ассистент кафедры онкологии, </p><p>SPIN-код: 7650-2129, AuthorID: 805452, ResearcherID: B-7280-2017, SCOPUS: 57189622130</p><p>634028, Россия, Томск, ул. Савиных, д. 12/1</p><p>634050, Россия, Томск, Московский тракт, д. 2</p></bio><bio xml:lang="en"><p>Cand. of Sci. (Med), Senior Researcher of the Department of Thoracic Oncology, Research Institute of Oncology; Assistant at the Department of Oncology </p><p>SPIN-сode: 7650-2129, AuthorID: 805452, ResearcherID: B-7280-2017, SCOPUS: 57189622130</p><p>12/1, Savinykh st. Tomsk, 634028, Russia</p><p>2, Moskovskiy Hwy., Tomsk, 634050, Russia</p></bio><email xlink:type="simple">rodionov_eo@oncology.tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5365-9840</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Миллер</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Miller</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., ведущий научный сотрудник отделения торакальной онкологии</p><p>SPIN-код: 6510-9849, AuthorID: 558789, ResearcherID: C-8970-2012, SCOPUS: 56525429400 </p><p>634028, Россия, Томск, ул. Савиных, д. 12/1</p></bio><bio xml:lang="en"><p>Dr. of Sci. (Med), Head Researcher of the Department of Thoracic Oncology</p><p>SPIN-code: 6510-9849, AuthorID: 558789, ResearcherID: C-8970-2012, SCOPUS: 56525429400</p><p>12/1, Savinykh st. Tomsk, 634028, Russia</p></bio><email xlink:type="simple">miller_sv@sibmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0884-1838</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тузиков</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tuzikov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> д.м.н., заведующий отделением торакальной онкологии; профессор кафедры онкологии</p><p>SPIN-код: 5662-6431, AuthorID: 455003, ResearcherID: D-1176-2012, SCOPUS: 6507842873</p><p>634028, Россия, Томск, ул. Савиных, д. 12/1</p><p>634050, Россия, Томск, Московский тракт, д. 2</p><p> </p></bio><bio xml:lang="en"><p>Dr. of Sci. (Med), Head of the Department of Thoracic Oncology, Professor of the Department of Oncology</p><p> 12/1, Savinykh st. Tomsk, 634028, Russia</p><p>2, Moskovskiy Hwy., Tomsk, 634050, Russia; </p><p>SPIN-code: 5662-6431, AuthorID: 455003, ResearcherID: D-1176-2012, SCOPUS: 6507842873 </p></bio><email xlink:type="simple">TuzikovSA@oncology.tomsk.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9054-0742</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефтеев</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Efteev</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>младший научный сотрудник отделения торакальной онкологии </p><p>634028, Россия, Томск, ул. Савиных, д. 12/1</p><p>SPIN-код: 3474-4654, AuthorID: 978000</p></bio><bio xml:lang="en"><p>Junior Researcher of the Department of Thoracic Oncology</p><p>12/1, Savinykh st. Tomsk, 634028, Russia</p><p> SPIN-code: 3474-4654, AuthorID: 978000 </p></bio><email xlink:type="simple">efteyco@rambler.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7599-1211</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маркович</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Markovich</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>младший научный сотрудник отделения торакальной онкологии 634028, Россия, Томск, ул. Савиных, д. 12/1</p><p>SPIN-код: 2954-8330, AuthorID: 968514 </p></bio><bio xml:lang="en"><p>Junior Researcher of the Department of Thoracic Oncology</p><p>12/1, Savinykh st. Tomsk, 634028, Russia;</p><p>SPIN-code: 2954-8330, AuthorID: 968514 </p></bio><email xlink:type="simple">vitalii.markovich.87@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6015-7032</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Миллер</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Miller</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>студентка 4-го курса лечебного факультета</p><p>634050, Россия, Томск, Московский тракт, д. 2</p><p>SPIN: 3384-4789 </p></bio><bio xml:lang="en"><p>4th year medical student</p><p>2, Moskovskiy Hwy., Tomsk, 634050, Russia</p><p>SPIN: 3384-4789 </p></bio><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт онкологии, Томский национальный исследовательский медицинский центр Российской академии наук;&#13;
Сибирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Scientific Institution «Tomsk National Research Medical Center» of the Russian Academy of Sciences;</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-исследовательский институт онкологии, Томский национальный исследовательский медицинский центр Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Oncology, Federal State&#13;
Budgetary Scientific Institution «Tomsk National Research Medical Center» of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Научно-исследовательский институт онкологии, Томский национальный исследовательский медицинский центр Российской академии наук;&#13;
Сибирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Oncology, Federal State Budgetary Scientific Institution «Tomsk National Research Medical Center» of the Russian Academy of Sciences;&#13;
Federal State Budgetary Educational Institution of Higher Education «Siberian State Medical University» of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Научно-исследовательский институт онкологии, Томский национальный исследовательский медицинский центр Российской академии наук</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Oncology, Federal State Budgetary Scientific Institution «Tomsk National Research Medical Center» of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Сибирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Education «Siberian State Medical University» of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>07</day><month>12</month><year>2019</year></pub-date><volume>0</volume><issue>19</issue><fpage>132</fpage><lpage>136</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Родионов Е.О., Миллер С.В., Тузиков С.А., Ефтеев Л.А., Маркович В.А., Миллер Д.С., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Родионов Е.О., Миллер С.В., Тузиков С.А., Ефтеев Л.А., Маркович В.А., Миллер Д.С.</copyright-holder><copyright-holder xml:lang="en">Rodionov E.O., Miller S.V., Tuzikov S.A., Efteev L.A., Markovich V.A., Miller D.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/5298">https://www.med-sovet.pro/jour/article/view/5298</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>иммунотерапия</kwd><kwd>пембролизумаб</kwd><kwd>немелкоклеточный рак легкого</kwd><kwd>аутоиммунный гипотиреоз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>immunotherapy</kwd><kwd>pembrolizumab</kwd><kwd>non-small-cell lung cancer</kwd><kwd>autoimmune hypothyroidism</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Цыганов М.М., Родионов Е.О., Дерюшева И.В., Миллер С.В., Ибрагимова М.К., Писарева Л.Ф. и др. 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Clin Lung Cancer. 2017;18(5):559-564. doi: 10.1016/j.cllc.2017.01.012.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
