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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2019-19-138-143</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-5308</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКОЕ НАБЛЮДЕНИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL OBSERVATION</subject></subj-group></article-categories><title-group><article-title>Клинический пример длительного контроля диссеминированного перстневидноклеточного рака желудка на фоне химиотерапии второй линии лечения в комбинации с бевацизумабом</article-title><trans-title-group xml:lang="en"><trans-title>Clinical example of long-term control of disseminated signet-ring cell carcinoma of the stomach against the background of chemotherapy of the second line of treatment in combination with bevacizumab</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5039-6360</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Титова</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Titova</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-онколог онкологического отделения лекарственных методов лечения (химиотерапевтического) №1 Научно-исследовательского института клинической онкологии имени академика РАН и РАМН Н.Н. Трапезникова</p><p>115478, Россия, Москва, Каширское шоссе, д. 24 </p></bio><bio xml:lang="en"><p>Oncologist at the Oncology Department of Medicinal Methods of Treatment (Chemotherapy) No. 1 of the Scientific ResearchInstitute of Clinical Oncology named after Academician of RAS and RAMS N.N. Trapeznikov</p><p>24, Kashirskoye sh., 115478, Moscow, Russia </p></bio><email xlink:type="simple">tatiana.titovadoc@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1693-0523</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бесова</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Besova</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., старший научный сотрудник онкологического отделения лекарственных методов лечения (химиотерапевтического) №1 Научно-исследовательского института клинической онкологии имени академика РАН и РАМН Н.Н. Трапезникова</p><p>115478, Россия, Москва, Каширское шоссе, д. 24 </p></bio><bio xml:lang="en"><p>Cand. of Sci. (Med), Senior Researcher at the Oncology Department of Medicinal Methods of Treatment (Chemotherapy) No. 1 of the Scientific Research Institute of Clinical Oncology named after Academician of RAS and RAMS N.N. Trapeznikov</p><p>24, Kashirskoye sh., 115478, Moscow, Russia </p></bio><email xlink:type="simple">besovans@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8936-3590</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Артамонова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Artamonova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., заведующая онкологическим отделением лекарственных методов лечения (химиотерапевтического) №1 Научно-исследовательского института клинической онкологии имени академика РАН и РАМН Н.Н. Трапезникова</p><p>115478, Россия, Москва, Каширское шоссе, д. 24 </p></bio><bio xml:lang="en"><p>Dr. of Sci. (Med), Head of the Oncology Department of Medicinal Methods of Treatment (Chemotherapy) No. 1 of the Scientific Research Institute of Clinical Oncology named after Academician of RAS and RAMS N.N. Trapeznikov</p><p>24, Kashirskoye sh., 115478, Moscow, Russia </p></bio><email xlink:type="simple">artamonovaE@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Institution «N.N.Blokhin Russian Cancer Research Centre» of the Ministry  of Health of Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>07</day><month>12</month><year>2019</year></pub-date><volume>0</volume><issue>19</issue><fpage>138</fpage><lpage>143</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Титова Т.А., Бесова Н.С., Артамонова Е.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Титова Т.А., Бесова Н.С., Артамонова Е.В.</copyright-holder><copyright-holder xml:lang="en">Titova T.A., Besova N.S., Artamonova E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/5308">https://www.med-sovet.pro/jour/article/view/5308</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>рак желудка</kwd><kwd>бевацизумаб</kwd><kwd>вторая линия терапии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>stomach cancer</kwd><kwd>bevacizumab</kwd><kwd>second line of therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bray F., Ferlay J., Soerjomataram I., Siegel R.L., Torre L.A., Jemal A. 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