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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2020-1-130-133</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-5549</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АЛЛЕРГОЛОГИЯ И ИММУНОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ALLERGOLOGY AND IMMUNOLOGY</subject></subj-group></article-categories><title-group><article-title>Аллергический ринит у детей: современный взгляд на терапию</article-title><trans-title-group xml:lang="en"><trans-title>Allergic rhinitis in children: a modern view of therapy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7516-5756</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крутихина</surname><given-names>С. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Krutikhina</surname><given-names>S. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Крутихина Светлана Борисовна - кандидат медицнских наук, ассистент кафедры детских болезней Клинического института детского здоровья им. Н.Ф. Филатова.</p><p>119991, Москва, ул. Трубецкая, д. 8, стр. 2</p></bio><bio xml:lang="en"><p>Svetlana B. Krutikhina - Cand. of Sci. (Med), Assistant of the Department of ChiLdren's Diseases of the N.F. FiLatov CLinicaL Institute of ChiLdren's HeaLth.</p><p>8/2, Trubetskaya St., Moscow, 119991</p></bio><email xlink:type="simple">svetulkakru@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3364-610X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яблокова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yablokova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Яблокова Екатерина Александровна - кандидат медицнских наук, доцент кафедры детских болезней Клинического института детского здоровья им. Н.Ф. Филатова.</p><p>119991, Москва, ул. Трубецкая, д. 8, стр. 2</p></bio><bio xml:lang="en"><p>Ekaterina A. Yablokova - Cand. of Sci. (Med), Associate Professor of the Department of ChiLdren's Diseases of the N.F. FiLatov CLinicaL Institute of ChiLdren's HeaLth.</p><p>8/2, Trubetskaya St., Moscow, 119991</p></bio><email xlink:type="simple">catcom@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>08</day><month>03</month><year>2020</year></pub-date><volume>0</volume><issue>1</issue><fpage>130</fpage><lpage>133</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Крутихина С.Б., Яблокова Е.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Крутихина С.Б., Яблокова Е.А.</copyright-holder><copyright-holder xml:lang="en">Krutikhina S.B., Yablokova E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/5549">https://www.med-sovet.pro/jour/article/view/5549</self-uri><abstract><p>В последние десятилетия во всем мире отмечается рост распространенности аллергических заболеваний. В промышленно развитых странах распространение аллергического ринита достигает до 40%. Симптомы аллергического ринита могут негативно влиять на качество жизни пациентов, нарушать сон, а также способствовать плохой успеваемости в школе. При аллергическом рините отмечаются характерные изменения эпителия слизистой оболочки носовой полости: метаплазия бокаловидных клеток; слущивание эпителия; снижение числа клеток с подвижными ресничками; потеря ресничек эпителиальными клетками; инфильтрация слизистой оболочки клетками воспаления; утолщение базальной мембраны. Симптомы аллергического ринита включают ринорею, затруднение носового дыхания, зуд и чихание. Современные классификации аллергического ринита учитывают этиологию, длительность симптомов и их тяжесть, патофизиологические изменения. Часто аллергический ринит дебютирует у детей до 6 лет, которому часто предшествует сенсибилизация. Алгоритм ведения пациентов с аллергическим ринитом предусматривает четыре основных метода, которые необходимы одновременно: обучение пациентов, в т. ч. детей и их родителей, элиминация аллергенов, фармакотерапия, иммунотерапия. Элиминационные мероприятия крайне важны для больных с аллергическим ринитом, но не всегда возможно полностью исключить контакт с причинным аллергеном. Выбор медикаментозной терапии зависит от формы и клинической выраженности заболевания, возраста пациента (возрастные ограничения препарата), наличия препарата в аптеках и его цены, а также приемлемости и удовлетворенности пациента конкретным методом лечения. Интраназальные антигистаминные препараты показали высокую эффективность в уменьшении таких симптомов, как чихание, ринорея, зуда, в меньшей степени - заложенность носа. Интраназальные антигистаминные препараты также имеют более быстрое начало действия, чем оральные антигистаминные препараты. Заложенность носа при этом наиболее эффективно облегчается деконгестантами.</p></abstract><trans-abstract xml:lang="en"><p>In recent decades, there has been an increase in the prevalence of allergic diseases around the world. In industrialized countries, the prevalence of allergic rhinitis reaches up to 40%. Symptoms of allergic rhinitis can have a negative impact on patients’ quality of life, disturb sleep, and contribute to poor school performance. In allergic rhinitis, characteristic changes of the nasal mucous membrane epithelium are noted: metaplasia of goblet cells; exfoliation of the epithelium; decrease in number of cells with mobile cilia; loss of cilia by epithelial cells; infiltration of mucous membrane by inflammatory cells; thickening of basal membrane. Symptoms of allergic rhinitis include rhinorrhoea, obstructed nasal breathing, itching and sneezing. Modern classifications of allergic rhinitis take into account the etiology, duration and severity of symptoms and pathophysiological changes. Allergic rhinitis often debut in children under 6, which is often preceded by sensitization. The algorithm of management of patients with allergic rhinitis has four main methods that are necessary simultaneously: training of patients, including children and their parents, elimination of allergens, pharmacotherapy, immunotherapy. Elimination measures are very important for patients with allergic rhinitis, but it is not always possible to completely eliminate contact with the causal allergen. The choice of drug therapy depends on the form and clinical severity of the disease, the age of the patient (age restriction of the drug), the availability of the drug in pharmacies and its price, as well as the acceptability and satisfaction of the patient with the specific treatment method. Intranasal antihistamines have been shown to be highly effective in reducing symptoms such as sneezing, rhinorrhoea, itching, and to a lesser extent - nasal congestion. Intranasal antihistamines also have faster onset than oral antihistamines. Nasal congestion is most effectively facilitated by decongestants.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>аллергический ринит</kwd><kwd>дети</kwd><kwd>антигистаминные препараты</kwd><kwd>лечение</kwd><kwd>деконгестанты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>allergic rhinitis</kwd><kwd>children</kwd><kwd>antihistamines</kwd><kwd>treatment</kwd><kwd>decongestants</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Белов В.А. Основные принципы аллергического ринита в педиатрической практике. 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