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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2020-11-124-130</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-5761</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭНДОКРИНОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ENDOCRINOLOGY</subject></subj-group></article-categories><title-group><article-title>Гипотиреоз: лекция для врачей первичного звена</article-title><trans-title-group xml:lang="en"><trans-title>Hypothyroidism: a lecture for primary care physicians</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2770-1205</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панфилова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Panfilova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Панфилова Елена Александровна, врач-эндокринолог </p><p>117036, Москва, ул. Дмитрия Ульянова, д. 11</p></bio><bio xml:lang="en"><p>Elena A. Panfilova, Endocrinologist </p><p>11, Dmitry Ulyanov St., Moscow, 117036</p></bio><email xlink:type="simple">e4erepanova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9963-6783</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исаева</surname><given-names>М. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Isaeva</surname><given-names>M. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Исаева Мария Петровна, клинический ординатор </p><p>117036, Москва, ул. Дмитрия Ульянова, д. 11</p></bio><bio xml:lang="en"><p>Mariya P. Isaeva, Resident Medical Practitioner </p><p>11, Dmitry Ulyanov St., Moscow, 117036</p></bio><email xlink:type="simple">impdoctorx@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8520-8702</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трошина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Troshina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трошина Екатерина Анатольевна, член-корр. РАН, д.м.н., профессор, заместитель директора по координации эндокринологической службы, руководитель отдела терапевтической эндокринологии </p><p>117036, Москва, ул. Дмитрия Ульянова, д. 11</p></bio><bio xml:lang="en"><p>Ekaterina A. Troshina, Corr.-Member. RAS, Dr. of Sci. (Med), Professor, Deputy Director for Coordination of Endocrinology Service, Head of Department of Therapeutic Endocrinology </p><p>11, Dmitry Ulyanov St., Moscow, 117036</p></bio><email xlink:type="simple">troshina@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр эндокринологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center for Endocrinology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>06</day><month>08</month><year>2020</year></pub-date><volume>0</volume><issue>11</issue><fpage>124</fpage><lpage>130</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Панфилова Е.А., Исаева М.П., Трошина Е.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Панфилова Е.А., Исаева М.П., Трошина Е.А.</copyright-holder><copyright-holder xml:lang="en">Panfilova E.A., Isaeva M.P., Troshina E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/5761">https://www.med-sovet.pro/jour/article/view/5761</self-uri><abstract><p>Распространенность гипотиреоза в популяции велика. Частота манифестного гипотиреоза в мире, по разным данным, составляет 0,2–2,0%, субклинического — до 10% у женщин и до 3% у мужчин, а у лиц старшей возрастной группы (старше 70 лет) достигает 14%, при этом большинство случаев гипотиреоза приходится на первичный гипотиреоз. Таким образом, врач любой специальности в своей практике имеет вероятность встретить пациента с гипотиреозом как с установленным диагнозом или столкнуться с необходимостью проведения дифференциальной диагностики различных патологических состояний с гипотиреозом. В статье представлена классификация гипотиреоза, основанная на этиологических аспектах, описана клиническая картина заболевания, отдельное внимание уделено так называемым маскам гипотиреоза, что, с нашей точки зрения, может быть полезным для врача любой специальности, приведены доступные методы диагностики данного синдрома (особое внимание уделено лабораторным методам), а также цели и принципы лечения, освещена необходимость контроля лабораторных показателей в динамике на фоне лечения. Кроме того, приведены особенности коррекции гипотиреоза во время беременности, представлены особенности подбора доз препаратов в зависимости от возраста и коморбидности пациента. Отличительной особенностью и целью данной статьи, с нашей точки зрения, является ее потенциальная польза не только для врачей-эндокринологов, но и для других специалистов в области здравоохранения.</p></abstract><trans-abstract xml:lang="en"><p>The prevalence of hypothyroidism in the population is high. The frequency of manifest hypothyroidism in the world, according to various data, is 0.2–2.0%, subclinical one – up to 10% for women and up to 3% for men, and in the older age group (over 70 years) reaches 14%, with the majority of cases of hypothyroidism accounted for primary hypothyroidism. Thus, a doctor of any specialty in his practice is likely to meet a patient with hypothyroidism: both with the established diagnosis, and face the need for differential diagnosis of various pathological conditions with hypothyroidism. This article presents a classification of hypothyroidism based on etiological aspects, describes the clinical picture of the disease, pays special attention to the so-called «masks» of hypothyroidism, which, in our view, can be useful for a doctor of any specialty, provides available methods for diagnosing this syndrome (special attention is paid to laboratory methods), as well as the goals and principles of treatment, highlights the need to monitor laboratory indicators in dynamics against the background of treatment. In addition, the features of correction of hypothyroidism during pregnancy are given. The article presents the peculiarities of selecting drug doses depending on the patient’s age and comorbidity. The distinctive feature and the purpose of this article, from our point of view, is its potential benefits not only for endocrinologists, but also for other health professionals.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гипотиреоз</kwd><kwd>маски гипотериоза</kwd><kwd>аутоиммунный тиреоидит</kwd><kwd>тиреотропный гормон</kwd><kwd>щитовидная железа</kwd><kwd>лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hypothyroidism</kwd><kwd>masks of hypothyroidism</kwd><kwd>autoimmune thyroiditis</kwd><kwd>thyroid-stimulating hormone</kwd><kwd>thyroid gland</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Aoki Y., Belin R.M., Clickner R., Jeffries R., Phillips L., Mahaffey K.R. 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