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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2020-13-58-64</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-5787</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭКСТРАГЕНИТАЛЬНЫЕ ЗАБОЛЕВАНИЯ И БЕРЕМЕННОСТЬ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXTRAGENITAL DISEASES AND PREGNANCY</subject></subj-group></article-categories><title-group><article-title>Опыт организации скрининга патологии щитовидной железы при беременности в регионе йодного дефицита</article-title><trans-title-group xml:lang="en"><trans-title>Experience in organizing screening of thyroid pathology during pregnancy in the region of iodine deficiency</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8551-5895</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Булгакова</surname><given-names>А. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Bulgakova</surname><given-names>A. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Булгакова Альфия Зуфаровна - врач-эндокринолог.</p><p>450078, Уфа, ул. Кирова, д. 52</p></bio><bio xml:lang="en"><p>Alfiya Z. Bulgakova - endocrinologist.</p><p>52, Kirov St., Ufa, 450078</p></bio><email xlink:type="simple">alfia_bulg@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6217-1812</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фазлыева</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Fazlyeva</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Фазлыева Эльза Ахметовна - кандидат медицинских наук, главный врач.</p><p>450078, Уфа, ул. Кирова, д. 52</p></bio><bio xml:lang="en"><p>Elza A. Fazlyeva, Cand. of Sci. (Med.), Director.</p><p>52, Kirov St., Ufa, 450078</p></bio><email xlink:type="simple">ufadoctor@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6685-8603</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галиева</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Galieva</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галиева Гузель Ахметовна –доктор медицинских наук профессор кафедры факультетской терапии, БГМУ; врач-терапевт, Клиника ЗЖ.</p><p>450008, Уфа, ул. Ленина, д. 3; 450078, Уфа, ул. Кирова, д. 52</p></bio><bio xml:lang="en"><p>Guzel A. Galieva - Dr. of Sci. (Med.), Professor of the Department of Faculty therapy, BSMU; internist at the Medical center Women’s Health.</p><p>3, Lenin St., Ufa, 450008; 52, Kirov St., Ufa, 450078</p></bio><email xlink:type="simple">gmukhetdinova@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9658-5952</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Измайлова</surname><given-names>Р. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Izmailova</surname><given-names>R. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Измайлова Рената Азатовна - администратор, Клиника ЗЖ; студентка 6-го курса по специальности Лечебное дело БГМУ.</p><p>450008, Уфа, ул. Ленина, д. 3; 450078, Уфа, ул. Кирова, д. 52</p></bio><bio xml:lang="en"><p>Renata A. Izmailova - administrator at the Medical center “Women’s Health”; 52, Kirov St., Ufa, 450078, Russia; a 6th-year student of the specialty “Medicine” BSMU/</p><p>3, Lenin St., Ufa, 450008; 52, Kirov St., Ufa, 450078</p></bio><email xlink:type="simple">renleila@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Клиника Здоровье женщины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical center Women’s Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Клиника Здоровье женщины; Башкирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical center Women’s Health; Bashkir State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>12</day><month>10</month><year>2020</year></pub-date><volume>0</volume><issue>13</issue><fpage>58</fpage><lpage>64</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Булгакова А.З., Фазлыева Э.А., Галиева Г.А., Измайлова Р.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Булгакова А.З., Фазлыева Э.А., Галиева Г.А., Измайлова Р.А.</copyright-holder><copyright-holder xml:lang="en">Bulgakova A.Z., Fazlyeva E.A., Galieva G.A., Izmailova R.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/5787">https://www.med-sovet.pro/jour/article/view/5787</self-uri><abstract><sec><title>Введение</title><p>Введение. Нарушение функции щитовидной железы оказывает существенное влияние на течение беременности и здоровье будущего ребенка. Но при этом сама беременность влияет на выработку тиреоидных гормонов, особенно на фоне предшествующей тиреопатии, а также на фоне йодного дефицита в регионе.</p></sec><sec><title>Цель работы</title><p>Цель работы. Оценить структуру патологии щитовидной железы и методические подходы к оптимизации оказания помощи беременным для своевременной профилактики и раннего выявления дисфункции щитовидной железы на примере работы клиники «Здоровье женщины» в регионе йодного дефицита (Республика Башкортостан).</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведен анализ функции щитовидной железы у 450 беременных, состоявших на учете в клинике в 2019 г. Гипотиреоз, как субклинический, так и манифестный, выявлен у 18,6 и 8,7% беременных соответственно.</p></sec><sec><title>Результаты исследования</title><p>Результаты исследования. Наблюдение беременных проводилось совместно акушером-гинекологом и эндокринологом (с выполнением регламентированного рекомендациями Минздрава РФ комплекса исследований). Из общего числа наблюдаемых 438 беременных женщин проживали в регионе с недостаточным потреблением йода (Республика Башкортостан). Полученные результаты существенно превышают литературные данные, что обусловливает необходимость разработки и внедрения региональных программ по ранней диагностике дисфункции щитовидной железы и ее своевременной коррекции у беременных в условиях йодного дефицита. Внедрено обязательное обследование функции щитовидной железы у всех беременных на ранних сроках.</p></sec><sec><title>Заключение</title><p>Заключение. С учетом данных о влиянии на ТТГ этнической принадлежности, обеспеченности региона проживания йодом, можно предположить, что референсные значения ТТГ во время беременности могут быть различными в разных регионах и у разных категорий женщин. Открытыми для обсуждения остаются критерии диагностики и показания для назначения заместительной терапии левотироксином натрия для лечения гипотиреоза у беременных.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Thyroid gland dysfunction has significant effects on the course of pregnancy and unborn child’s health. But at the same time, pregnancy itself affects the production of thyroid hormones, especially on the top of already administered thyropathy, as well as against the background of iodine deficiency in the region.</p></sec><sec><title>Objective of the study</title><p>Objective of the study. Assess the thyroid pathology profile and methodological approaches to optimization of care for pregnant women for timely prevention and early detection of thyroid gland dysfunction through the example of the operation of Woman’s Health Clinic in the iodine-deficient region (Republic of Bashkortostan).</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The analysis of thyroid function was carried out in 450 pregnant women, who were registered with the clinic in 2019. Both subclinical and manifest hypothyroidism was detected in 18.6 and 8.7% of pregnant women, respectively. Results of the study. The observation was carried out jointly by an obstetrician-gynecologist and an endocrinologist (along with the implementation of a set of studies regulated by the recommendations of the Ministry of Health of the Russian Federation). Of the total number of the observed patients, 438 pregnant women were living in the region with insufficient iodine intake (Republic of Bashkortostan). The results obtained significantly exceed the literature data, which necessitates the development and implementation of regional programs for early diagnosis of thyroid dysfunction and its timely management in pregnant women under conditions of iodine deficiency.</p><p>Mandatory examination of thyroid function in all women in the early stages of pregnancy has been introduced.</p></sec><sec><title>Conclusion</title><p>Conclusion. Taking into account the effect of ethnicity on TSH and the iodine status in the region of residence, it can be assumed that the reference TSH values during pregnancy may be different in different regions and in different categories of women. Diagnostic criteria and indications for prescribing replacement therapy using levothyroxine sodium to treat hypothyroidism in pregnant women remain open for discussion.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>гормоны</kwd><kwd>щитовидная железа</kwd><kwd>беременность</kwd><kwd>гипотиреоз</kwd><kwd>йодный дефицит</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hormones</kwd><kwd>thyroid</kwd><kwd>pregnancy</kwd><kwd>hypothyroidism</kwd><kwd>iodine deficiency</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Приказ Министерства здравоохранения Российской Федерации от 1 ноября 2012 г. № 572н «Об утверждении Порядка оказания медицинской помощи по профилю «акушерство и гинекология (за исключением использования вспомогательных репродуктивных технологий)». 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