medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2020-13-179-187medsovet-5802Research ArticleРЕПРОДУКТИВНОЕ ЗДОРОВЬЕ И ВРТREPRODUCTIVE HEALTH AND ARTМужское бесплодие: до и после эпохи коронавируса SARS-CoV-2Male infertility: before and after the era of SARS-CoV-2https://orcid.org/0000-0001-8219-5216ОвчинниковР. И.OvchinnikovR. I.

Овчинников Руслан Игоревич - кандидат медицинских наук, заведующий по клинической работе отделения андрологии и урологии.

117997, Москва, ул. Академика Опарина, д. 4

Ruslan I. Ovchinnikov - Cand. of Sci. (Med.), Head of Clinical Affairs, Department of Andrology and Urology.

riododc@rambler.ruhttps://orcid.org/0000-0002-9128-2714ГамидовС. И.GamidovS. I.

Гамидов Сафар Исраилович - доктор медицинских наук, заведующий отделением андрологии и урологии, НМИЦАГП им.академика В.И. Кулакова; профессор кафедры урологии и оперативной нефрологии, ПМГМУ им.И.М. Сеченова.

117997, Москва, ул. Академика Опарина, д. 4; 119991, Москва, ул. Трубецкая, д. 8, стр. 2

Safail I. Gamidov - Dr. of Sci. (Med.), Head of Department of Andrology and Urology; Professor of Department of Urology and Operative Nephrology.

4, Oparin St., Moscow, 117997; 8, Bldg. 2, Trubetskaya St., Moscow, 119991

safargamidov@yandex.ruhttps://orcid.org/0000-0002-3038-4792ПоповаА. Ю.PopovaA. Yu.

Попова Алина Юрьевна - кандидат медицинских наук, старший научный сотрудник отделения андрологии и урологии.

117997, Москва, ул. Академика Опарина, д. 4

Alina Yu. Popova - Cand. of Sci. (Med.), Senior Researcher, Department of Andrology and Urology.

Alina-dock@ya.ruhttps://orcid.org/0000-0001-8117-3197ИжбаевС. Х.IzhbaevS. Kh.

Ижбаев Сергей Хасанович - кандидат медицинских наук, уролог, андролог, врач ультразвуковой диагностики отделения андрологии и урологии.

117997, Москва, ул. Академика Опарина, д. 4

Sergey Kh. Izhbaev - Cand. of Sci. (Med.), urologist, andrologist, ultrasound specialist, Department of Andrology and Urology.

4, Oparin St., Moscow, 117997

izhbaev-sergei@mail.ruНациональный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени академика В.И. КулаковаРоссияNational Medical Research Center of Obstetrics, Gynecology and Perinatology named after Academician V.I. KulakovRussian FederationНациональный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени академика В.И. Кулакова; Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет)РоссияNational Medical Research Center of Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov; I.M. Sechenov First Moscow State Medical University (Sechenov University)Russian Federation202013102020013179187Copyright © Овчинников Р.И., Гамидов С.И., Попова А.Ю., Ижбаев С.Х., 20202020Овчинников Р.И., Гамидов С.И., Попова А.Ю., Ижбаев С.Х.Ovchinnikov R.I., Gamidov S.I., Popova A.Y., Izhbaev S.K.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/5802

Установлено, что мужчины болеют коронавирусом в 1,5 раза чаще, чем женщины, но в то же время 95% из них переносят инфекцию в легкой форме.

Существует вопросы, которые требуют научного объяснения: почему мужчины болеют чаще и более восприимчивы, чем женщины, проходит ли вирус через гемато-тестикулярный барьер, проникает ли он в семенную жидкость, если ли влияние SARS-CoV-2 на выработку андрогенов, поражается ли яичко и каковы последствия этого поражения, каково непосредственное влияние вируса и связанных с ним проблем (таких как социальные проблемы, изоляция, карантин, психологические проблемы, малоподвижный образ жизни и пр.), прежде всего на сексуальную функцию, сексуальное поведение и репродукцию в целом?

В обзорной статье рассмотрена ситуация, связанная с пандемией коронавируса SARS-CoV-2 в 2020 г. и ее влиянием на мужское здоровье. Приводятся данные по эпидемиологии, аспектам патогенеза, особенностям новой коронавирусной инфекции у мужчин. Озвучены рекомендации международных обществ по репродукции (ASRM, ESHRE, РАРЧ) по проведению программ вспомогательных репродуктивных технологий (ВРТ) в эпоху пандемии. Представлены разные точки зрения на влияние тестостерона на заболеваемость мужчин. Показана важность оксидативного стресса сперматозоидов и антиоксидантной терапии мужского бесплодия. Изложены задачи международного проекта по изучению влияния коронавирусной инфекции SARS-CoV-2 и ее последствий на здоровье мужчин. Опубликовано приглашение к сотрудничеству с отечественными и зарубежными специалистами в области урологии и андрологии на базе ФГБУ «Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени академика В.И. Кулакова» Министерства здравоохранения Российской Федерации.

It has been found that men are infected with the coronavirus 1.5 times more often than women, but at the same time 95% of them have mild infection.

There are questions that require a scientific explanation: why are men infected more often and more susceptible than women, does the virus cross the blood-testicular barrier, can it be found in the seminal fluid, does SARS-CoV-2 have an effect on the production of androgens, is the testicle affected and what are the consequences of this damage, what is the direct effect of a virus and virus-associated problems (such as social problems, isolation, quarantine, psychological problems, sedentary lifestyle, etc.) primarily on sexual function, sexual behaviour and reproduction in general?

The review article examines the SARS-CoV-2 pandemic-associated situation in 2020 and its effect on the men’s health. The article provides data on epidemiology, aspects of pathogenesis, features of new coronavirus infection in men. The authors announced the international reproduction associations (ASRM, ESHRE, RAHR) recommendations for the implementation of assisted reproductive technology (ART) programs in the era of the pandemic. Different points of view on the effect of testosterone on the disease incidence in men are presented. The importance of sperm oxidative stress and antioxidant therapy for male infertility has been shown. The tasks of an international project for the study of SARS-CoV-2 coronavirus infection and its consequences on men’s health are outlined. An invitation to collaboration with domestic and foreign specialists in the field of urology and andrology under the aegis of the National Medical Research Center of Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov of the Ministry of Health of the Russian Federation has been published.

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The authors declare that there are no conflicts of interest present.