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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2021-2-94-100</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-6017</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРАКТИКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PRACTICE</subject></subj-group></article-categories><title-group><article-title>Невротическое расстройство, головная боль, стресс: опыт ведения коморбидного пациента и роль препаратов магния</article-title><trans-title-group xml:lang="en"><trans-title>Neurotic disorder, headache, and stress: experience of managing a comorbid patient and the role of magnesium drugs</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2752-4109</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Головачева</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovacheva</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Головачева Вероника Александровна, к.м.н., ассистент кафедры нервных болезней и нейрохирургии Института клинической медицины</p><p>119991, Москва, ул. Трубецкая, д. 8, стр. 2</p></bio><bio xml:lang="en"><p>Veronika A. Golovacheva, Cand. of Sci. (Med.), Assistant of the Department of Nervous Diseases and Neurosurgery of the Institute of Clinical Medicine</p><p>8, Bldg. 2, Trubetskaya St., Moscow, 119991</p></bio><email xlink:type="simple">xoxo.veronicka@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3833-532X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Табеева</surname><given-names>Г. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Tabeeva</surname><given-names>G. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Табеева Гюзель Рафкатовна, д.м.н., профессор кафедры нервных болезней и нейрохирургии Института клинической медицины</p><p>119991, Москва, ул. Трубецкая, д. 8, стр. 2</p></bio><bio xml:lang="en"><p>Gyuzyal R. Tabeeva, Dr. of Sci. (Med.), Professor of the Department of Nervous Diseases and Neurosurgery of the Institute of Clinical Medicine</p><p>8, Bldg. 2, Trubetskaya St., Moscow, 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>11</day><month>03</month><year>2021</year></pub-date><volume>0</volume><issue>2</issue><fpage>94</fpage><lpage>100</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Головачева В.А., Табеева Г.Р., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Головачева В.А., Табеева Г.Р.</copyright-holder><copyright-holder xml:lang="en">Golovacheva V.A., Tabeeva G.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/6017">https://www.med-sovet.pro/jour/article/view/6017</self-uri><abstract><p>В практике неврологов и терапевтов часто встречаются пациенты с жалобами на головную боль, повышенную утомляемость и раздражительность. Наиболее частые причины головной боли у пациентов амбулаторного звена – первичные головные боли (мигрень и головная боль напряжения). Недостаток сна, стресс, симптомы тревоги и депрессии, злоупотребление обезболивающими препаратами – наиболее распространенные факторы, которые способствуют учащению головных болей. Дефицит магния – еще один фактор, роль которого обсуждается в учащении первичных головных болей, в развитии невротических расстройств и депрессии. К клиническим проявлениям самого дефицита магния принято относить такие неспецифические симптомы, как утомляемость, тревожность, раздражительность, онемения в конечностях, спазмы в ногах, нарушения сна и др.Дефицит магния распространен среди населения развитых стран, особенно среди женщин репродуктивного возраста, часто встречается при беременности, приеме оральных контрацептивов. Магний участвует в регуляции деятельности нервной системы, в нервно-мышечной передаче, сердечной деятельности, регуляции сосудистого тонуса, свертывании крови и метаболизме костной ткани. Дефицит магния ассоциирован с такими заболеваниями, как ишемическая болезнь сердца, гипертоническая болезнь, сахарный диабет 2-го типа, болезнь Альцгеймера, мигрень, остеопороз, депрессия, невротические расстройства (паническое расстройство, генерализованная тревога, различные фобии), фибромиалгический синдром. Стресс может приводить к снижению уровня магния в организме, а недостаток магния, в свою очередь, снижает толерантность к стрессовым ситуациям. Своевременная диагностика и адекватное лечение дефицита магния и ассоциированных состояний представляют собой важные клинические задачи.Представлен клинический случай пациентки с невротическим расстройством, головной болью и дефицитом магния, продемонстрирована эффективность междисциплинарного подхода, включающего образовательную беседу, адекватную терапию для купирования головной боли, терапию препаратом магния и психологические методы. Рассмотрена роль дефицита магния в развитии различных неврологических заболеваний. Обсуждаются наиболее эффективные для терапии соединения магния. Приведены принципы диагностики и лечения пациентов с дефицитом магния.</p></abstract><trans-abstract xml:lang="en"><p>In the practice of neurologists and therapists, patients with complaints of headache, increased fatigue, and irritability are common. The most frequent causes of headaches in ambulatory patients are primary headaches (migraine and tension headaches). Lack of sleep, stress, symptoms of anxiety and depression, and abuse of analgesic drugs are the most common factors that contribute to the frequency of headaches. Magnesium deficiency is another factor, the role of which has been discussed in the frequency of primary headaches, in the development of neurotic disorders and depression. Clinical manifestations of magnesium deficiency itself usually include such nonspecific symptoms as fatigue, anxiety, irritability, numbness in the extremities, leg cramps, sleep disorders, etc.Magnesium deficiency is widespread among the population of developed countries, especially among women of reproductive age, often occurs during pregnancy, while taking oral contraceptives. Magnesium is involved in the regulation of the nervous system, neuromuscular transmission, cardiac activity, regulation of vascular tone, blood clotting and bone tissue metabolism. Magnesium deficiency is associated with diseases such as coronary heart disease, hypertension, type 2 diabetes, Alzheimer’s disease, migraine, osteoporosis, depression, neurotic disorders (panic disorder, generalized anxiety, various phobias), and fibromyalgia syndrome. Stress can lead to a decrease in magnesium levels in the body, and magnesium deficiency, in turn, reduces tolerance to stressful situations. Timely diagnosis and adequate treatment of magnesium deficiency and associated conditions represent important clinical challenges.The clinical case of a patient with neurotic disorder, headache and magnesium deficiency is presented, and the effectiveness of an interdisciplinary approach including an educational talk, adequate therapy for headache management, magnesium drug therapy and psychological methods is demonstrated. The role of magnesium deficiency in the development of various neurologic diseases is reviewed. The most effective magnesium compounds for therapy are discussed. Principles of diagnosis and treatment of patients with magnesium deficiency are presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>стресс</kwd><kwd>невротическое расстройство</kwd><kwd>головная боль</kwd><kwd>тревога</kwd><kwd>лечение</kwd><kwd>когнитивно-поведенческая терапия</kwd><kwd>магний</kwd><kwd>витамин В6</kwd></kwd-group><kwd-group xml:lang="en"><kwd>stress</kwd><kwd>neurotic disorder</kwd><kwd>headache</kwd><kwd>anxiety</kwd><kwd>treatment</kwd><kwd>cognitive behavioral therapy</kwd><kwd>magnesium</kwd><kwd>vitamin B6</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Парфенов В.А., Головачева В.А. Хроническая боль и ее лечение в неврологии. М.: ГЭОТАР-Медиа; 2018. 288 с.</mixed-citation><mixed-citation xml:lang="en">Parfenov V.A., Golovacheva V.A. 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