medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2021-4-170-173medsovet-6105Research ArticleГИНЕКОЛОГИЯGYNECOLOGYЛатентный дефицит железа и железодефицитная анемия беременных: последствия для матери и плода, возможные пути решенияLatent iron deficiency and iron deficiency anemia in pregnancy: effects on maternal and fetal health, possible ways to solve the problemhttps://orcid.org/0000-0002-2882-8163МагомедоваА. П.MagomedovaA. P.

Магомедова Аида Пирмагомедовна, клинический ординатор

117997, Москва, ул. Академика Опарина, д. 4

Aida P. Magomedova, Resident Medical Practitioner

4, Academician Oparin St., Moscow, 117997

aidoxxa21@mail.ruhttps://orcid.org/0000-0002-6090-586XЛомоваН. А.LomovaN. A.

Ломова Наталья Анатольевна, кандидат медицинских наук, научный сотрудник института акушерства

117997, Москва, ул. Академика Опарина, д. 4

Natalia A. Lomova, Cand. Sci. (Med.), Research Associate of the Institute of Obstetrics

4, Academician Oparin St., Moscow, 117997

natasha-lomova@yandex.ruhttps://orcid.org/0000-0003-0025-3182КарапетянТ. Э.KarapetyanT. Eh.

Карапетян Тамара Эдуардовна, доктор медицинских наук, старший научный сотрудник института акушерства

117997, Москва, ул. Академика Опарина, д. 4

Tamara Eh. Karapetyan, Dr. Sci. (Med.), Senior Research Associate of the Institute of Obstetrics

4, Academician Oparin St., Moscow, 117997

tomamed02@mail.ruhttps://orcid.org/0000-0001-5601-1241АмираслановЭ. Ю.AmiraslanovE. Yu.

Амирасланов Эльрад Юсифович, кандидат медицинских наук, заведующий акушерским отделением

117997, Москва, ул. Академика Опарина, д. 4

Elrad Yu. Amiraslanov, Cand. Sci. (Med.), Head of Department of Obstetrics

4, Academician Oparin St., Moscow, 117997

eldis@mail.ruНациональный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени академика В.И. КулаковаРоссияKulakov National Medical Research Center of Obstetrics, Gynecology and PerinatologyRussian Federation20211904202104170173Copyright © Магомедова А.П., Ломова Н.А., Карапетян Т.Э., Амирасланов Э.Ю., 20212021Магомедова А.П., Ломова Н.А., Карапетян Т.Э., Амирасланов Э.Ю.Magomedova A.P., Lomova N.A., Karapetyan T.E., Amiraslanov E.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/6105

В настоящее время дефицит железа как с анемией, так и без нее у беременных встречается достаточно часто. Фактически в мире почти 30% женщин репродуктивного возраста страдают анемией, а распространенность ее во время беременности оценивается в 38%. Хотя дефицит железа (ЖД) – не единственная причина анемии, но наиболее часто встречаемая. Стратегии снижения уровня анемии среди беременных часто оказываются неэффективными, и по данным ВОЗ тяжелая анемия может существенно увеличить риск материнской смертности. Таким образом, текущие рекомендации по  скринингу и  лечению ЖД-анемии (ЖДA) у беременных и новорожденных требуют пересмотра. Тяжелая анемия может существенно увеличить риск материнской смертности и отрицательно сказаться на развитии плода и новорожденного. В этом обзоре мы анализируем доступные данные об эпидемиологии и последствиях дефицита железа у матерей и младенцев, текущие стратегии лечения и рекомендации по скринингу, а также изучаем лечение ЖДА у беременных и новорожденных и проблему низкой комплаентности пациентов с латентным дефицитом железа. Одним из составляющих успеха в лечении ЖДА и особенно латентных форм дефицита железа у беременных женщин является непрерывный продолжительный курс приема пероральных форм железа. Зачастую низкая комплаентность пациенток приводит к  плохим результатам терапии и  неверным выводам о  неэффективности пероральных форм железа в  борьбе с  ЖДА. Проанализированные нами данные говорят о возможности увеличения приверженности к лечению ЖДА беременных женщин.

Iron deficiency with or without anemia in pregnant women is quite common today. In fact, anemia affects nearly 30% of women of reproductive age, and its prevalence among pregnant women is estimated to be 38% worldwide. Although iron deficiency (IR) is not the only cause of anemia, it is the most prevalent one. Anemia-reduction strategies among pregnant women are often ineffective, and severe anemia can greatly increase the risk of maternal mortality, as reported by WHO. Now therefore, the current guidelines for screening and treatment of ID-anemia (IDA) in pregnant women and new-borns require change. Severe anemia can greatly increase the risk of maternal death and adversely affect a developing fetus and new-born. In this review, we analyse the available data on the epidemiology and the effects of iron deficiency on mothers and infants, current treatment strategies and screening recommendations, as well as examine the treatment of IDA in pregnant women and newborns and the problem of poor compliance in patients with latent iron deficiency. A continuous long-term course of administration of oral iron supplements is one of the components of success in the treatment of IDA, and particularly latent forms of iron deficiency in pregnant women. It is often the case that poor patients’ compliance with therapy leads to poor treatment outcomes and misleading conclusions about the ineffectiveness of oral iron dosage forms in the battle against IDA. The data we have analysed suggest the possibility of increasing compliance with IDA treatment in pregnant women.

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The authors declare that there are no conflicts of interest present.