medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2021-7-184-191medsovet-6153Research ArticleДИССЕРТАНТDISSERTANTГестационный сахарный диабет: особенности течения и исходы беременности в реальной клинической практикеGestational diabetes mellitus: peculiarities of course and pregnancy outcomes in real clinical practicehttps://orcid.org/0000-0001-5512-6899УшановаФ. О.UshanovaF. O.

Ушанова Фатима Омариевна - ассистент кафедры эндокринологии лечебного факультета.

117997, Россия, Москва, ул. Островитянова, д. 1.

Fatima O. Ushanova - Assistant of the Department of Endocrinology of the Medical Faculty, Pirogov Russian National Research Medical University.

1, Ostrovityanov St., Moscow, 117997.

fati_2526@mail.ruhttps://orcid.org/0000-0002-3656-0312ЛобановаК. Г.LobanovaK. G.

Лобанова Кристина Геннадьевна - ассистент кафедры эндокринологии лечебного факультета.

117997, Москва, ул. Островитянова, д. 1.

SPIN-код: 6044-1684

Kristina G. Lobanova - Assistant of the Department of Endocrinology of the Medical Faculty, Pirogov Russian National Research Medical University.

1, Ostrovityanov St., Moscow, 117997.

miss.sapog@mail.ruhttps://orcid.org/0000-0002-6276-2305ПереходовС. Н.PerekhodovS. N.

Переходов Сергей Николаевич – доктор медицинских наук, профессор, главный врач.

109263, Москва, ул. Шкулева, д. 4.

SPIN-код: 8770-6877

Sergey N. Perekhodov - Dr. Sci. (Med.), Professor, Chief Medical Officer, Demikhov City Clinical Hospital;.

4, Shkulev St., Moscow, 109263.

s.perekhodov@bk.ruРоссийский национальный исследовательский медицинский университет имени Н.И. ПироговаРоссияPirogov Russian National Research Medical UniversityRussian FederationГородская клиническая больница имени В.П. ДемиховаРоссияDemikhov City Clinical HospitalRussian Federation20211205202107184191Copyright © Ушанова Ф.О., Лобанова К.Г., Переходов С.Н., 20212021Ушанова Ф.О., Лобанова К.Г., Переходов С.Н.Ushanova F.O., Lobanova K.G., Perekhodov S.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/6153Введение

Введение. По данным различных авторов, некомпенсированный гестационный сахарный диабет сопровождается развитием множества осложнений со стороны матери и плода. Однако опубликованных данных о распространенности ГСД и его осложнений в реальной клинической практике в нашей стране недостаточно.

Цель

Цель. Оценить распространенность ГСД среди беременных женщин ЮВАО г. Москвы, проанализировать основные факторы риска, особенности течения и исходы беременности у женщин с ГСД.

Материалы и методы

Материалы и методы. Ретроспективный анализ данных первичной документации 510 беременных женщин, которым был установлен диагноз «ГСД» в течение 2019 г. Проведен сравнительный анализ осложнений и исходов беременности в зависимости от срока выявления ГСД.

Результаты и обсуждение

Результаты и обсуждение. За период 2019 г. ГСД диагностирован 510 беременным женщинам из 5 000 наблюдавшихся. Средний возраст женщин составил 31,9 ± 4,8 (ДИ 95% 31,5-32,3). Чаще всего диагноз устанавливался в первом триместре беременности -224 беременным (43,9%), во втором триместре - 31,8% (162), 18,6% (95) - в третьем триместре. Средние значения глюкозы венозной плазмы - 5,43 [5,25; 5,7] ммоль/л, гликированного гемоглобина - 5,19 ± 0,4% (ДИ 95% 5,15-5,24). Для достижения компенсации ГСД преимущественно было достаточно диетотерапии - 84,3%. Осложнения беременности наблюдались у 123 женщин (24,1%). Неблагоприятные исходы беременности зарегистрированы у 153 женщин с ГСД из 213 проанализированных (71,8%). Не выявлено статистически значимой разницы в исходах беременности в зависимости от срока выявления ГСД.

Выводы

Выводы. Распространенность ГСД в ЮВАО г. Москвы составила 10,2%, что согласуется с данными различных эпидемиологических работ в других регионах. При этом развитие неблагоприятных исходов беременности остается на высоком уровне. В связи с этим целесообразно проведение дальнейших исследовательских работ, направленных на оценку основных факторов, влияющих на течение и исходы беременности.

Introduction

Introduction. According to various authors, uncompensated gestational diabetes mellitus (GDM) is accompanied by the development of many complications affecting the mother and fetus. However, published data on the prevalence of GDM and its complications in real clinical practice in our country are insufficient.

Aim

Aim. To estimate the prevalence of GDM among pregnant women in the South-Eastern Administrative District of Moscow, to analyze the main risk factors, the features of the course and pregnancy outcomes in women with GDM.

Materials and Methods

Materials and Methods. Retrospective analysis of primary records of 510 pregnant women who were diagnosed with GDM during 2019. A comparative analysis of pregnancy complications and outcomes depending on the age of diagnosis of GDM was performed.

Results and Discussion

Results and Discussion. During 2019, 510 pregnant women out of 5,000 women observed were diagnosed with GSD. The mean age of the women was 31.9 ± 4.8 (95% CI 31.5-32.3). Most frequently, 224 pregnant women (43.9%) were diagnosed in the 1st trimester of pregnancy, 31.8% (162) in the 2nd trimester, and 18.6% (95) in the 3rd trimester. Mean venous plasma glucose values were 5.43 [5.25; 5.7] mmol/L, and glycated hemoglobin was 5.19 ± 0.4% (95% CI 5.15-5.24). Diet therapy was predominantly sufficient to achieve GSD compensation - 84.3%. Complications of pregnancy were observed in 123 women (24.1%). Unfavorable pregnancy outcomes were recorded in 153 women with GSD out of 213 women analyzed (71.8%). There was no statistically significant difference in pregnancy outcomes depending on the age of diagnosis of GDM.

Conclusions

Conclusions. The prevalence of GDM in the South-Eastern Administrative District of Moscow was 10.2%, which is consistent with the data of various epidemiological studies in other regions. The development of adverse pregnancy outcomes remains at a high level. Therefore, it is advisable to conduct further research aimed at assessing the main factors influencing the course and outcomes of pregnancy.

 

 

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The authors declare that there are no conflicts of interest present.