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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2021-6-92-98</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-6167</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АЛЛЕРГОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ALLERGOLOGY</subject></subj-group></article-categories><title-group><article-title>Современный взгляд на терапию аллергического ринита при его сочетании с бронхиальной астмой</article-title><trans-title-group xml:lang="en"><trans-title>The modern view of treatment of allergic rhinitis and it’s combination with bronchial asthma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4785-7074</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смирнов</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Smirnov</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Смирнов Дмитрий Сергеевич, младший научный сотрудник отделения «бронхиальная астма»</p><p>115478, Москва, Каширское шоссе, д. 24</p></bio><bio xml:lang="en"><p>Dmitriy S. Smirnov, Junior Research Associate, Bronchial Asthma Department</p><p>24, Kashirskoye Shosse, Moscow, 115478</p></bio><email xlink:type="simple">allergologsmirnov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3250-0694</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Курбачева</surname><given-names>О. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurbacheva</surname><given-names>O. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Курбачева Оксана Михайловна, доктор медицинских наук, профессор, заведующая отделением «бронхиальная астма»</p><p>115478, Москва, Каширское шоссе, д. 24</p></bio><bio xml:lang="en"><p>Oksana M. Kurbacheva, Dr. Sci. (Med.), Professor, Head of Bronchial Asthma Department</p><p>24, Kashirskoye Shosse, Moscow, 115478</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Государственный научный центр «Институт иммунологии»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Research Center – Institute of Immunology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>12</day><month>05</month><year>2021</year></pub-date><volume>0</volume><issue>6</issue><fpage>92</fpage><lpage>98</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Смирнов Д.С., Курбачева О.М., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Смирнов Д.С., Курбачева О.М.</copyright-holder><copyright-holder xml:lang="en">Smirnov D.S., Kurbacheva O.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/6167">https://www.med-sovet.pro/jour/article/view/6167</self-uri><abstract><p>В последние годы отмечен значительный рост распространенности заболеваний носа и околоносовых пазух. Воспалительные заболевания слизистой оболочки полости носа (риниты) чаще всего характеризуются как синдром, в котором пациент испытывает некоторую комбинацию постоянных назальных симптомов, включая ринорею, чихание, заложенность носа, зуд и жжение в полости носа. Среди хронических форм ринита большое место занимает аллергический ринит наряду с вазомоторным, инфекционным, гипертрофическим, катаральным и атрофическим ринитами. Аллергический ринит представляет собой существенную социальную и медико-экономическую проблему, поскольку заметно снижает качество жизни пациентов и требует значительных затрат на лечение. Эта нозология встречается в практике врачей всех специальностей, тем не менее постановка правильного диагноза и назначение адекватной терапии могут занимать долгие месяцы и годы. В настоящий момент широко обсуждается концепция «единых дыхательных путей», которая демонстрирует тесную связь между аллергическим ринитом и бронхиальной астмой и доказывает, что воспалительный ответ может поддерживаться и усиливаться взаимосвязанными механизмами. Поэтому больные с аллергическим ринитом должны быть обследованы на предмет наличия бронхиальной астмы. В свою очередь, больным с бронхиальной астмой необходимо провести диагностику аллергического ринита, лечение должно быть направлено и на подавление аллергического воспаления как в верхних, так и в нижних дыхательных путях. В данной статье рассматриваются современные диагностические и терапевтические подходы к пациентам с данными заболеваниями, позволяющие эффективно и своевременно выявить аллергический ринит и начать соответствующее адекватное лечение. Также в статье обсуждается целесообразность применения комбинированной терапии левоцетиризином и монтелукастом при вышеуказанных нозологиях.</p></abstract><trans-abstract xml:lang="en"><p>In recent years, there has been a significant increase in the prevalence of diseases of the nose and paranasal sinuses. Inflammatory diseases of the mucous membrane nasal cavities (rhinitis) are most commonly characterized as a syndrome in which the patient experiences some combination of persistent nasal symptoms, including rhinorrhea, sneezing, nasal congestion, itching and burning in the nasal cavity. Among the chronic forms of rhinitis, allergic rhinitis occupies a large place along with vasomotor, infectious, hypertrophic, catarrhal and atrophic rhinitis. Allergic rhinitis is a significant social and medico-economic problem, since it significantly reduces the quality of life of patients and requires significant treatment costs. This nosology is found in the practice of doctors of all specialties, however, the correct diagnosis and the appointment of adequate therapy can take many months and years. Currently, the concept of “common airways” is widely discussed, which demonstrates the close relationship between allergic rhinitis and bronchial asthma and proves that the inflammatory response can be supported and enhanced by interrelated mechanisms. Therefore, patients with allergic rhinitis should be examined for the presence of bronchial asthma. In turn, patients with bronchial asthma need to diagnose allergic rhinitis, and treatment should be aimed at suppressing allergic inflammation in both the upper and lower respiratory tract. This article discusses modern diagnostic and therapeutic approaches to patients with these diseases, which make it possible to efficiently and timely identify allergic rhinitis and initiate appropriate adequate treatment. The article also discusses the feasibility of using combined therapy with levocetirizine and montelukast in the above nosologies.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>аллергический ринит</kwd><kwd>диагностика</kwd><kwd>лечение</kwd><kwd>монтелукаст</kwd><kwd>левоцетиризин</kwd><kwd>аллерген-специфическая иммунотерапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>allergic rhinitis</kwd><kwd>diagnostic</kwd><kwd>treatment</kwd><kwd>montelukast</kwd><kwd>levocetirizine</kwd><kwd>allergen-specific immunotherapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Wise S.K., Lin S.Y., Toskala E., Orlandi R.R., Akdis C.A., Alt J.A. et al. International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis. 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