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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2021-8-53-60</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-6197</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЗАБОЛЕВАНИЯ КОЖИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DERMAL DISEASES</subject></subj-group></article-categories><title-group><article-title>Опыт применения многокомпонентного геля на основе троксерутина, гепарина и декспантенола в реабилитации пациентов после косметологических вмешательств</article-title><trans-title-group xml:lang="en"><trans-title>Experience of applying a multi-component gel based on troxerutin, heparin sodium and dexpanthenol in the rehabilitation of patients after cosmetic procedures</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3386-1467</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Острецова</surname><given-names>М. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ostretsova</surname><given-names>M. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Острецова Мария Николаевна, к.м.н., ассистент кафедры дерматовенерологии и аллергологии с курсом иммунологии медицинского института</p><p>117198, Москва, ул. Миклухо-Маклая, д. 6</p></bio><bio xml:lang="en"><p>Maria N. Ostretsova, Cand. Sci. (Med.), Teaching Assistant, Department of Dermatovenereology and Allergology with the Course of Immunology, Institute of Medicine</p><p>6, Miklukho-Maklai St., Moscow, 117198</p></bio><email xlink:type="simple">ostretsova-mn@rudn.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8394-2700</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кореневская</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Korenevskaya</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кореневская Айя, ассистент кафедры дерматовенерологии и аллергологии с курсом иммунологии медицинского института</p><p>117198, Москва, ул. Миклухо-Маклая, д. 6</p></bio><bio xml:lang="en"><p>Aija Korenevskaya, Teaching Assistant, Department of Dermatovenereology and Allergology with the Course of Immunology, Institute of Medicine</p><p>6, Miklukho-Maklai St., Moscow, 117198</p></bio><email xlink:type="simple">aija.korenevska@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0767-8821</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Касихина</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kasikhina</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Касихина Елена Игоревна, к.м.н., доцент кафедры дерматовенерологии и аллергологии с курсом иммунологии медицинского института; врач-дерматовенеролог</p><p>117198, Москва, ул. Миклухо-Маклая, д. 6</p><p>119071, Москва, Ленинский проспект, д. 17</p></bio><bio xml:lang="en"><p>Elena I. Kasikhina, Cand. Sci. (Med.), Associate Professor, Department of Dermatovenereology and Allergology with the Course of Immunology, Institute of Medicine; Dermatologist</p><p>6, Miklukho-Maklai St., Moscow, 117198</p><p>17, Leninskiy Ave., Moscow, 119071</p></bio><email xlink:type="simple">kasprof@bk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5723-6573</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жукова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhukova</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жукова Ольга Валентиновна, д.м.н., профессор, заведующая кафедрой дерматовенерологии и аллергологии с курсом иммунологии медицинского института; главный врач</p><p>117198, Москва, ул. Миклухо-Маклая, д. 6</p><p>119071, Москва, Ленинский проспект, д. 17</p></bio><bio xml:lang="en"><p>Olga V. Zhukova, Dr. Sci. (Med.), Professor, Head of the Department of Dermatovenereology and Allergology with the Course of Immunology, Institute of Medicine; Chief Medical Officer</p><p>6, Miklukho-Maklai St., Moscow, 117198</p><p>17, Leninskiy Ave., Moscow, 119071</p></bio><email xlink:type="simple">klinderma@inbox.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский университет дружбы народов</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российский университет дружбы народов; Московский научно-практический&#13;
центр дерматовенерологии и косметологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia; Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>07</day><month>06</month><year>2021</year></pub-date><volume>0</volume><issue>8</issue><fpage>53</fpage><lpage>60</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Острецова М.Н., Кореневская А., Касихина Е.И., Жукова О.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Острецова М.Н., Кореневская А., Касихина Е.И., Жукова О.В.</copyright-holder><copyright-holder xml:lang="en">Ostretsova M.N., Korenevskaya A., Kasikhina E.I., Zhukova O.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/6197">https://www.med-sovet.pro/jour/article/view/6197</self-uri><abstract><p>В статье приводятся актуальная классификация осложнений косметологических процедур, а также клинический опыт применения многокомпонентного геля на основе троксерутина, гепарина и декспантенола в реабилитации пациентов после косметологических процедур, осложнившихся экхимозами, гематомами и отеками на примере двух пациентов. В первом случае пациентке, 30 лет, были выполнены аугментация и коррекция асимметрии губ с использованием наполнителя на основе стабилизированной гиалуроновой кислоты. Процедура осложнилась образованием гематом и отеком. С целью ускорения заживления и минимизации отека, гематом и риска вторичной инфекции пациентке были назначены: обработка инъецированной зоны 0,05%-м водным раствором хлоргексидина биглюконата 1 р/сут, нанесение многокомпонентного геля на основе троксерутина, гепарина и декспантенола 2 р/сут в течение 10 дней. К 5-му дню были отмечены значительное уменьшение отека области губ, уменьшение гематом. К 8-му дню отмечалось почти полное рассасывание гематом. Во втором случае пациентке, 42 года, была выполнена процедура биоревитализации препаратом на основе нестабилизированной гиалуроновой кислоты, осложнившаяся появлением экхимоза размером до 12 мм в диаметре и отечности в периорбитальной зоне. В качестве постпроцедурной реабилитации был назначен 0,05%-й водный раствор хлоргексидина биглюконата 1 р/сут и многокомпонентный гель на основе троксерутина, гепарина и декспантенола в режиме 2 р/сут на 7 дней. К 4-му дню отмечались клиническое улучшение, исчезновение отечности, изменение цвета и сокращение размера экхимоза до 4 мм, полное исчезновение отмечено к 6-му дню. Кроме того, авторами рассмотрены свойства каждого из основных составляющих, входящих в состав многокомпонентного препарата. Применение многокомпонентного геля на основе троксерутина, гепарина и декспантенола в качестве вспомогательного средства ускорило процесс разрешения сформировавшихся осложнений и позволило значительно сократить реабилитационный период у данных пациентов, что позволяет рекомендовать его в качестве средства постпроцедурной реабилитации.</p></abstract><trans-abstract xml:lang="en"><p>The article reports an up-to-date classification of complications of cosmetic procedures and two clinical cases where multicomponent gel based on troxerutin, heparin sodium and depanthenol was used to rehabilitate patients after cosmetic procedures complicated by ecchymosis, hematomas and edema. In the first case a 30-year-old patient had a procedure to give greater volume to her lips and to correct their asymmetry with hyaluronic acid filler. The procedure was complicated by the formation of hematomas and edema. To minimize the edema and hematomas and to avoid the risk of infection the patient was prescribed 0.05% aqueous solution of chlorhexidine bi-gluconate once per day and taking of multicomponent gel based on troxerutin, heparin sodium and depanthenol two times per day for seven days. By the fifth day there was observed a significant decrease in edema of the lip area and almost complete resorption of hematomas. In the second case a 42-year-old patient had a procedure of a biorevitalization with unstabilized hyaluronic acid complicated by the appearance of ecchymosis up to 12 mm in diameter and edema in the periorbital zone. A 0.05% aqueous solution of chlorhexidine bi-gluconate once per day and a multicomponent gel based on troxerutin, heparin sodium and dexpanthenol twice per day for seven days were prescribed as post-procedural rehabilitation. By the fourth day clinical improvement was noted. The edema disappeared, the color changed, the size of the ecchymosis decreased to 4 mm. The ecchymosis disappeared completely on the sixth day. In addition, the main characteristics of troxerutin, heparin sodium and depanthenol as components of a multicomponent gel were considered. A multicomponent gel based on troxerutin, heparin sodium and depanthenol as supportive aid helped to get complications completely cleaned out and significantly reduced the rehabilitation period for these patients. The authors consider it possible to recommend it as a means of post-procedural rehabilitation.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>троксерутин</kwd><kwd>гепарин натрия</kwd><kwd>декспантенол</kwd><kwd>осложнения инъекционных процедур</kwd><kwd>гематомы</kwd><kwd>экхимозы</kwd><kwd>косметология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>troxerutin</kwd><kwd>heparin sodium</kwd><kwd>dexpanthenol</kwd><kwd>complications of injection procedures</kwd><kwd>hematomas</kwd><kwd>ecchymosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Singh K., Nooreyezdan S. Nonvascular Complications of Injectable Fillers-Prevention and Management. Indian J Plast Surg. 2020;53(3):335–343. doi: 10.1055/s-0040-1721872.</mixed-citation><mixed-citation xml:lang="en">Singh K., Nooreyezdan S. Nonvascular Complications of Injectable Fillers-Prevention and Management. 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