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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2021-12-146-153</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-6343</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПУЛЬМОНОЛОГИЯ, ЛОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BRONCHOPULMONOLOGY, OTORHINOLARYNGOLOGY</subject></subj-group></article-categories><title-group><article-title>Коморбидный больной хронической обструктивной болезнью легких и ишемической болезнью сердца: возможности ранней диагностики легочной гипертензии в амбулаторных условиях</article-title><trans-title-group xml:lang="en"><trans-title>Comorbid patient with chronic obstructive pulmonary disease and coronary heart disease: opportunities for early diagnosis of pulmonary hypertension in outpatient settings</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2914-8570</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Калашник</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kalashnik</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент кафедры поликлинической терапии с курсом общей врачебной практики (семейной медицины) факультета повышения квалификации и профессиональной переподготовки специалистов, 350063, Краснодар, ул. Митрофана Седина, д. 4;</p><p>заведующая приемным отделением, 350072, Краснодар, ул. Московская, д. 96</p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Associate Professor at the of Department Polyclinic Therapy with Course of General Medical Practice (Family Medicine) of the Faculty of Advanced Training and Professional Retraining of Specialists, 4, Mitrofan Sedin St., Krasnodar, 3500063;</p><p>Head of the Reception Department, 96, Moskovskaya St., Krasnodar, 350072</p></bio><email xlink:type="simple">darunika@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8945-5399</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корольчук</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Korolchuk</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>350063, Краснодар, ул. Митрофана Седина, д. 4</p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Associate Professor at the Department of Polyclinic Therapy with Course of General Medical Practice (Family Medicine) of the Faculty of Advanced Training and Professional Retraining of Specialists,</p><p>4, Mitrofan Sedin St., Krasnodar, 350063</p></bio><email xlink:type="simple">ir.korolchuk@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кубанский государственный медицинский университет; &#13;
Клиническая больница «РЖД-Медицина»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kuban State Medical University; &#13;
 Clinical Hospital Russian Railways-Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Кубанский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kuban State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>15</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>12</issue><fpage>146</fpage><lpage>153</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Калашник Д.Н., Корольчук И.С., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Калашник Д.Н., Корольчук И.С.</copyright-holder><copyright-holder xml:lang="en">Kalashnik D.N., Korolchuk I.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/6343">https://www.med-sovet.pro/jour/article/view/6343</self-uri><abstract><sec><title>Введение</title><p>Введение. Коморбидный пациент с хронической обструктивной болезнью легких (ХОБЛ) в сочетании с ишемической болезнью сердца (ИБС) имеет неблагоприятный прогноз вследствие раннего развития легочной гипертензии (ЛГ). В исследовании изучалась возможность выявления ЛГ с использованием стратегии активной ее верификации у амбулаторных пациентов с ХОБЛ и стабильной стенокардией.</p></sec><sec><title>Цель</title><p>Цель. Оценить частоту ЛГ у больных ХОБЛ легкой и средней степени тяжести течения в сочетании с ИБС и возможность использования эхокардиографического критерия «площадь правого предсердия» для доказательства ЛГ.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование включены 52 амбулаторных пациента со средним возрастом 62,8 ± 8,14 года. Проводилась комплексная оценка шкалы одышки Борга, эхокардиографии, пульсоксиметрии в покое и после теста 6-минутной ходьбы (Т6МХ). Подвергнуты сравнительному анализу 2 группы пациентов в зависимости от развития ЛГ после Т6МХ.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Показано, что у пациентов c ХОБЛ (GOLD I-II) и стенокардией исходно ЛГ выявлялась в 3,3% случаев, а после Т6МХ у 63,3% больных. В данной группе после Т6МХ определялось повышение давления в легочной артерии с 18,5 ± 10,6 мм рт. ст. до 41,2 ± 12,5 мм рт. ст. (р &lt; 0,05). После физической нагрузки с повышением давления в легочной артерии отмечалось достоверное увеличение площади правого предсердия. Только у 1/3 больных с ЛГ определялась гипоксемия после Т6МХ.</p></sec><sec><title>Выводы</title><p>Выводы. Проба Т6М дает возможность выявить ЛГ более чем у половины больных ХОБЛ (GOLD I-II) и ИБС в условиях поликлиники. Увеличение площади правого предсердия по данным эхокардиографии, наряду с другими показателями морфофункциональных изменений правых отделов сердца, может быть дополнительным диагностическим критерием ЛГ у коморбидных пациентов ХОБЛ и ИБС. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. A comorbid patient with the chronic obstructive pulmonary disease (COPD) in combination with cardiovascular diseases (CHD) has a poor prognosis due to the early progression of the pulmonary hypertension (PH). The study surveyed an opportunity of the PH detection using an active PH verification strategy in outpatients with COPD and stable angina pectoris.</p></sec><sec><title>Goal</title><p>Goal. To evaluate the frequency of РH in patients with mild and moderate COPD in combination with CHD and the possibility of using the echocardiographic criterion «right atrial area» to prove РH.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study included 52 outpatient patients with an average age of 62.8 ± 8.14 years. A comprehensive assessment of the Borg dyspnea scale, echocardiography, pulse oximetry at rest and after the 6-minute walk test (6MWT) were carried out. Two groups of patients were compared depending on the development of РH after T6MX.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. It was shown that in patients with COPD (GOLD I-II) and angina pectoris, PH was initially detected in 3.3% of cases, and after the 6MWT in 63.3% of patients. In this group, after T6MX, an increase in pulmonary artery pressure was determined from 18.5 ± 10.6 mmHg to 41.2 ± 12.5 mmHg (p &lt; 0.05). After physical activity with increased pressure in the pulmonary artery, there was a significant increase in the area of the right atrium. Only 1/3 of patients with PH had hypoxemia after the 6MWT.</p></sec><sec><title>Conclusions</title><p>Conclusions. The T6M test makes it possible to detect РH in more than half of patients with COPD (GOLD I-II) and CHD in an outpatient setting. An enlargement in the area of the right atrium according to echocardiography, along with the other indicators of morphological and functional changes in the right heart, can be an additional diagnostic criterion for PH in comorbid patients with COPD and cardiovascular diseases. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая обструктивная болезнь легких</kwd><kwd>стенокардия</kwd><kwd>коморбидность</kwd><kwd>легочная гипертензия</kwd><kwd>эхокардиография</kwd><kwd>правое предсердие</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic obstructive pulmonary disease</kwd><kwd>angina pectoris</kwd><kwd>comorbidity</kwd><kwd>pulmonary hypertension</kwd><kwd>echocardiography</kwd><kwd>right atrium</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ghoorah K., De Soyza A., Kunadian V. 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