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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2021-12-276-284</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-6359</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭНДОКРИНОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ENDOCRINOLOGY</subject></subj-group></article-categories><title-group><article-title>Анализ тиреоидного статуса беременных женщин в регионе легкого йодного дефицита</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of the thyroid status of pregnant women in the region of mild iodine deficiency</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9253-8075</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Суплотова</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Suplotova</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заведующая курсом эндокринологии кафедры терапии Института непрерывного профессионального развития, </p><p>625023, Тюмень, ул. Одесская, д. 54</p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor, Head of Endocrinology Course, Therapy Department, Institute of Continuing Professional Development, </p><p>54, Odesskaya St., Tyumen, 625023</p></bio><email xlink:type="simple">suplotovala@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4663-0289</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макарова</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarova</surname><given-names>O. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент, доцент курса эндокринологии кафедры терапии Института непрерывного профессионального развития, </p><p>625023, Тюмень, ул. Одесская, д. 54</p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Assistant Professor, Assistant Professor of the Endocrinology Course, Therapy Department, Institute of Continuing Professional Development, </p><p>54, Odesskaya St., Tyumen, 625023</p></bio><email xlink:type="simple">dr.makarova@yahoo.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2108-5309</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Максюкова</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Maksyukova</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>главный врач, </p><p>625027, Тюмень, ул. Холодильная, д. 58</p></bio><bio xml:lang="en"><p>Chief Physician, </p><p>58, Cholodilnaya St., Tyumen, 625027</p></bio><email xlink:type="simple">dr.maksyukova@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4729-7660</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смолина</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Smolina</surname><given-names>L. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>заведующая женской консультацией № 2, </p><p>625027, Тюмень, ул. Холодильная, д. 58</p></bio><bio xml:lang="en"><p>Head of Antenatal Clinic No. 2, </p><p>58, Cholodilnaya St., Tyumen, 625027</p></bio><email xlink:type="simple">dr.smolina@bk.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тюменский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tyumen State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Родильный дом №2</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Maternity Hospital №2</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Родильный дом № 2</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Maternity Hospital №2</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>18</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>12</issue><fpage>276</fpage><lpage>284</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Суплотова Л.А., Макарова О.Б., Максюкова Е.Н., Смолина Л.Н., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Суплотова Л.А., Макарова О.Б., Максюкова Е.Н., Смолина Л.Н.</copyright-holder><copyright-holder xml:lang="en">Suplotova L.A., Makarova O.B., Maksyukova E.N., Smolina L.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/6359">https://www.med-sovet.pro/jour/article/view/6359</self-uri><abstract><sec><title>Введение</title><p>Введение. Гормоны щитовидной железы играют важную роль во время беременности, обеспечивая органогенез, рост и развитие плода, участвуют в  формировании и  развитии головного мозга и  его структур, влияя на  когнитивные способности. Дисфункция щитовидной железы ассоциирована с  патологическим течением беременности и  родов, а  также негативным влиянием на плод. Йодный дефицит, сохраняющийся на всей территории России, создает предпосылки для более частого развития субклинического гипотиреоза и гипотироксинемии беременных. Поэтому раннее выявление дисфункции щитовидной железы в период гестации в регионе йодного дефицита является актуальным.</p></sec><sec><title>Цель</title><p>Цель. Оценить тиреоидный статус у беременных женщин в регионе йодного дефицита.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведено одноцентровое проспективное одновыборочное исследование в популяции беременных женщин, вставших на учет с июня 2019 г. по декабрь 2019 г. в женскую консультацию г. Тюмени.</p></sec><sec><title>Результаты</title><p>Результаты. По  результатам медико-биологического мониторинга йодного дефицита в  популяции беременных женщин г. Тюмени улучшилось йодное обеспечение, о  чем свидетельствует медианная концентрации йодурии 154,4  мкг/л, частота эндемического зоба составила 0,37%. Сплошной скрининг женщин в 1-м триместре беременности без тиреоидной патологии в анамнезе выявил субклинический гипотиреоз у 21,5% беременных, носительство антител к тиреопероксидазе установлено у 10,5% женщин.</p></sec><sec><title>Выводы</title><p>Выводы. Учитывая сохраняющуюся проблему йодного дефицита, широкое распространение субклинического гипотиреоза в популяции беременных женщин необходимо включить исследование тиреоидного статуса в стандарт обследования беременных при постановке на учет в женскую консультацию для ранней диагностики и своевременной терапии гипотиреоза. Также рекомендовано продолжить профилактические мероприятия, направленные на восполнение йодного дефицита, начиная с этапа прегравидарной подготовки. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Thyroid hormones play an important role during pregnancy, providing organogenesis, growth and development of the fetus, participate in the formation and development of the brain and its structures, affecting cognitive abilities. Thyroid dysfunction is associated with the pathological course of pregnancy and childbirth, as well as a negative effect on the fetus. Iodine deficiency, which persists throughout Russia, creates the preconditions for the more frequent development of subclinical hypothyroidism and hypothyroxinemia in pregnant women. Therefore, early detection of thyroid dysfunction during gestation in the region of iodine deficiency is relevant.</p></sec><sec><title>Aim</title><p>Aim. To assess the thyroid status in pregnant women in the region of iodine deficiency.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. A single-center, prospective, one-sample study was performed in a population of pregnant women registered from June 2019 to December 2019 to the antenatal clinic in Tyumen.</p></sec><sec><title>Results</title><p>Results. According to the results of biomedical monitoring of iodine deficiency in the population of pregnant women in Tyumen, iodine supply improved, as evidenced by the median concentration of ioduria 154.4 μg / l, the frequency of endemic goiter was 0.37%. Continuous screening of women in the 1st trimester of pregnancy without thyroid pathology revealed subclinical hypothyroidism in 21.5% of pregnant women, carriage of antibodies to thyroperoxidase was found in 10.5% of women.</p></sec><sec><title>Conclusions</title><p>Conclusions. Given the persisting problem of iodine deficiency, the widespread occurrence of subclinical hypothyroidism in the population of pregnant women, it is necessary to include the study of thyroid status in the standard of examination of pregnant women when registering in an antenatal clinic for early diagnosis and timely treatment of hypothyroidism. It is also recommended to continue preventive measures aimed at replenishing the iodine deficiency starting from the stage of pregravid preparation. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>щитовидная железа</kwd><kwd>гормоны</kwd><kwd>дисфункция</kwd><kwd>скрининг</kwd><kwd>беременность</kwd><kwd>йодурия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>thyroid gland</kwd><kwd>hormones</kwd><kwd>dysfunction</kwd><kwd>screening</kwd><kwd>pregnancy</kwd><kwd>ioduria</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Zimmermann M.B., Andersson M. Assessment of iodine nutrition in populations: past, present, and future. Nutrition Reviews. 2012;70(10):553–70. https://doi.org/10.1111/j.1753-4887.2012.00528.x.</mixed-citation><mixed-citation xml:lang="en">Zimmermann M.B., Andersson M. Assessment of iodine nutrition in populations: past, present, and future. 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