medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2021-17-128-135medsovet-6494Research ArticleБРОНХОПУЛЬМОНОЛОГИЯ, ОТОРИНОЛАРИНГОЛОГИЯBRONCHOPULMONOLOGY, OTORHINOLARYNGOLOGYПрименение растительного препарата в терапии острых тонзиллофарингитов у детейApplication of a herbal preparation in the therapy of acute tonzillopharyngitis in childrenhttps://orcid.org/0000-0003-1430-6708БорисоваО. В.BorisovaO. V.

Борисова Ольга Вячеславовна - доктор медицинских наук, профессор, заведующий кафедрой детских инфекций.

443099, Самара, ул. Чапаевская, 89

Olga V. Borisova, Dr. Sci. (Med.), Professor, Head of the Department of Children's Infections.

89, Chapaevs-kaya St., Samara, 443099

kaf_di@samsmu.ruhttps://orcid.org/0000-0002-4603-3209БочкареваН. М.BochkarevaN. M.

Бочкарева Наталия Михайловна - кандидат медицинских наук, доцент, доцент кафедры детских инфекций.

443099, Самара, ул. Чапаевская, 89

Natalia M. Bochkareva, Cand. Sci. (Med.), Associate Professor of the Department of Children's Infections.

89, Chapaevskaya St., Samara, 443099

kaf_di@samsmu.ruhttps://orcid.org/0000-0002-9712-862XПолежаеваН. С.PolezhaevaN. S.

Полежаева Наталья Сергеевна - кандидат медицинских наук, доцент, доцент кафедры детских инфекций.

443099, Самара, ул. Чапаевская, 89

Natalia S. Polezhaeva, Cand. Sci. (Med.), Associate Professor of the Department of Children's Infections.

89, Chapaevskaya St., Samara, 443099

kaf_di@samsmu.ruФранкА. А.FrankA. A.

Франк Анна Андреевна - аспирант кафедры детских инфекций.

443099, Самара, ул. Чапаевская, 89

Anna A. Frank, Postgraduate Student of the Department of Children's Infections.

89, Chapaevskaya St., Samara, 443099

kaf_di@samsmu.ruЯшкинаО. Н.YashkinaO. N.

Яшкина Ольга Николаевна - аспирант кафедры детских инфекций.

443099, Самара, ул. Чапаевская, 89

Olga N. Yashkina, Postgraduate Student of the Department of Children's Infections.

89, Chapaevskaya St., Samara, 443099

kaf_di@samsmu.ruСамарский государственный медицинский университетРоссияSamara State Medical UniversityRussian Federation202131102021017128135Copyright © Борисова О.В., Бочкарева Н.М., Полежаева Н.С., Франк А.А., Яшкина О.Н., 20212021Борисова О.В., Бочкарева Н.М., Полежаева Н.С., Франк А.А., Яшкина О.Н.Borisova O.V., Bochkareva N.M., Polezhaeva N.S., Frank A.A., Yashkina O.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/6494Введение

Введение. Тонзиллофарингит нередко сопровождает течение острых респираторных инфекций у детей (до 12-15%). Применение системных антибактериальных препаратов при вирусной этиологии болезни не показано, поэтому все больше возрастает интерес исследователей к использованию средств растительного происхождения. В многочисленных клинических испытаниях, проведенных по всему миру, жидкий экстракт корней пеларгонии сидовидной EPs® 7630 показал свои эффективность и безопасность при лечении острых респираторных инфекций, заболеваний лор-органов, острых бронхитов у взрослых и детей.

Цель

Цель. Оценить эффективность и безопасность препарата EPs® 7630 (Умкалор) при острых тонзиллофарингитах нестрептококковой этиологии у детей 2-6 лет в амбулаторных условиях.

Материалы и методы

Материалы и методы. Проведен проспективный анализ случаев лечения препаратом Умкалор острого тонзиллофарингита нестрептококковой этиологии на фоне острой респираторной инфекции у детей 2-6 лет (n = 23, первая группа). Группу сравнения (вторую) составили дети, получавшие стандартную терапию (n = 22). У всех пациентов не применялись системные антибиотики и противовирусные препараты. Исследование проведено в течение 6 мес. (2019-2020). Результаты исследования обработаны с применением программы Statistica 7.0 (StatSoft, США).

Результаты и обсуждение

Результаты и обсуждение. Терапия препаратом Умкалор у детей с острым тонзиллофарингитом способствовала ликвидации основных клинических симптомов болезни на 4-й день лечения (эффективность составила 69,9%, р < 0,05). Самым стойким симптомом была гиперемия миндалин и ротоглотки. Таким образом, период реконвалесценции наступал на 2 дня раньше по сравнению с детьми 2-й группы (р < 0,05). Умкалор обладал хорошей переносимостью, побочных нежелательных эффектов препарата не выявлено.

Выводы

Выводы. Препарат Умкалор можно рекомендовать для проведения монотерапии продолжительностью 7 дней пациентам с острым нестрептококковым тонзиллофарингитом в амбулаторных условиях при легком и среднетяжелом течении заболевания.

Introduction

Introduction. Tonsillopharyngitis often accompanies the course of acute respiratory infections in children (up to 12-15%). The use of systemic antibacterial drugs for viral etiology of the disease has not been shown, therefore, the interest of researchers in the use of herbal products is increasing. In numerous clinical trials conducted around the world, the liquid extract of the roots of Pelargonium sidoides EPs® 7630 has been shown to be effective and safe in the treatment of acute respiratory infections, acute tonsillopharyngitis, rhinosinusitis, acute bronchitis in adults and children.

Objective of the study

Objective of the study: assessment of the efficacy and safety of the drug EPs® 7630 (Umckalor) in acute tonsillopharyngitis of non-streptococcal etiology in children 2-6 years old on an outpatient basis.

Materials and methods

Materials and methods. A prospective analysis of cases of treatment with Umckalor for acute tonsillopharyngitis of non-streptococcal etiology against the background of acute respiratory infection in children 2-6 years old (n = 23, group 1) was carried out.

The comparison group (2) consisted of children receiving standard therapy (n = 22). Systemic antibiotics and antiviral drugs were not used in all patients. The study was conducted over 6 months (2019-2020). The research results were processed using the Statistica 7.0 software (StatSoft, USA).

Results and discussion

Results and discussion. Therapy with Umckalor in children with acute tonsillopharyngitis contributed to the elimination of the main clinical symptoms of the disease on the 4th day of treatment (efficiency was 69.9%, p < 0.05). The most persistent symptom was hyperemia of the tonsils and oropharynx. The period of convalescence occurred 2 days earlier than in the children of group 2 (p < 0.05). Umckalor was well tolerated, no side effects of the drug were identified.

Conclusions

Conclusions. The drug Umckalor can be recommended for monotherapy for 7 days in patients with acute non-streptococcal tonsillopharyngitis on an outpatient basis with mild and moderate disease.

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The authors declare that there are no conflicts of interest present.