medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2021-21-1-212-223medsovet-6626Research ArticleПЕДИАТРИЯPEDIATRICSДифференцированный подход к назначению препаратов декспантенола в практике педиатраDifferentiated approach to the prescription of dexpanthenol drugs in the practice of a pediatricianhttps://orcid.org/0000-0003-4200-4598ЗахароваИ. Н.ZakharovaI. N.

Захарова Ирина Николаевна, д.м.н., профессор, заслуженный врач РФ, заведующая кафедрой педиатрии имени академика Г.Н. Сперанского

125993, Москва, ул. Баррикадная, д. 2/1, стр. 1

Irina N. Zakharova, Dr. Sci. (Med.), Professor, Honoured Doctor of the Russian Federation, Head of the Department of Pediatrics named after G.N. Speransky

2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993

zakharova-rmapo@yandex.ruhttps://orcid.org/0000-0001-5249-1452ТвороговаТ. М.TvorogovaT. M.

Творогова Татьяна Михайловна, к.м.н., доцент кафедры педиатрии имени академика Г.Н. Сперанского

125993, Москва, ул. Баррикадная, д. 2/1, стр. 1

Tatiana M. Tvorogova, Cand. Sci. (Med.), Associate Professor of the Department of Pediatrics named after Academician G.N. Speransky

2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993

tvort@mail.ruБережнаяИ. В.BerezhnayaI. V.

Бережная Ирина Владимировна, к.м.н., доцент кафедры педиатрии имени академика Г.Н. Сперанского

125993, Москва, ул. Баррикадная, д. 2/1, стр. 1

Irina V. Berezhnaya, Cand. Sci. (Med.), Associate Professor of the Department of Pediatrics named after Academician G.N. Speransky

2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993

berezhnaya-irina26@yandex.ruhttps://orcid.org/0000-0002-0058-3803ПшеничниковаИ. И.PshenichnikovaI. I.

Пшеничникова Ирина Игоревна, к.м.н., ассистент кафедры педиатрии имени академика Г.Н. Сперанского

125993, Москва, ул. Баррикадная, д. 2/1, стр. 1

Irina I. Pshenichnikova, Cand. Sci. (Med.), Assistant Professor of the Department of Pediatrics named after Academician G.N. Speransky

2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993

bassarida@gmail.comhttps://orcid.org/0000-0003-0668-7336ДмитриеваЮ. А.DmitrievaYu. A.

Дмитриева Юлия Андреевна, к.м.н., доцент кафедры педиатрии имени Г.Н. Сперанского

125993, Москва, ул. Баррикадная, д. 2/1, стр. 1

Yulia A. Dmitrieva, Cand. Sci. (Med.), Associate Professor of the Department of Pediatrics named after Academician G.N. Speransky

2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993

jadmitrieva@mail.ruhttps://orcid.org/0000-0002-9524-8724ЦуцаеваА. Н.TsutsaevaA. N.

Цуцаева Анна Николаевна, ассистент кафедры факультетской педиатрии

355017,Ставрополь, ул. Мира, д. 310

 

Anna N. Tsutsaeva, Assistant of the Department of Pediatrics

310, Mira St., Stavropol, 355017

a.nicolaevnakasjanova@yandex.ruhttps://orcid.org/0000-0003-2395-4045МачневаЕ. Б.MachnevaE. B.

Мачнева Елена Борисовна, к.м.н., врач-гематолог отделения трансплантации костного мозга

119571, Москва, Ленинский проспект, д. 117

Elena B. Machneva, Cand. Sci. (Med.), Hematologist of the Department of Bone Marrow Transplantation

117, Leninskiy Ave., Moscow, 19571

lena.machneva@yandex.ruЮдинаА. Е.YudinaA. E.

Юдина Анастасия Евгеньевна, заведующая первым неонатологическим отделением, врач высшей квалификационной категории педиатрии

125373, Москва, ул. Героев Панфиловцев, д. 28

Anastasia E. Yudina, Head of the 1st Neonatology Department, Doctor of the Highest Qualification Category of Pediatrics

28, Geroev Panfilovtsev St., Moscow, 125373

yudina209@gmail.comПупыкинаВ. В.PupykinaV. V.

Пупыкина Виктория Викторовна, клинический ординатор кафедры педиатрии имени Г.Н. Сперанского

125993, Москва, ул. Баррикадная, д. 2/1, стр. 1

Viktoria V. Pupykina, Clinical Resident of the f the Department of Pediatrics named after Academician G.N. Speransky

2/1, Bldg. 1, Barrikadnaya St., Moscow, 125993

vika-pupykina@mail.ruРоссийская медицинская академия непрерывного профессионального образованияРоссияRussian Medical Academy of Continuous Professional EducationRussian FederationСтавропольский государственный медицинский университетРоссияStavropol State Medical UniversityRussian FederationРоссийская детская клиническая больница Российского национального исследовательского медицинского университета имени Н.И. ПироговаРоссияRussian Children’s Clinical Hospital of Pirogov National Medical Research UniversityRussian FederationДетская городская клиническая больница имени З.А. БашляевойРоссияBashlyaeva City Children’s Clinical Hospital of the Department of Healthcare of MoscowRussian Federation202107012022021-1212223Copyright © Захарова И.Н., Творогова Т.М., Бережная И.В., Пшеничникова И.И., Дмитриева Ю.А., Цуцаева А.Н., Мачнева Е.Б., Юдина А.Е., Пупыкина В.В., 20222022Захарова И.Н., Творогова Т.М., Бережная И.В., Пшеничникова И.И., Дмитриева Ю.А., Цуцаева А.Н., Мачнева Е.Б., Юдина А.Е., Пупыкина В.В.Zakharova I.N., Tvorogova T.M., Berezhnaya I.V., Pshenichnikova I.I., Dmitrieva Y.A., Tsutsaeva A.N., Machneva E.B., Yudina A.E., Pupykina V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/6626

В статье приведены сведения об особенностях строения, развития кожи ребенка и о дифференцированном подходе к назначению препаратов декспантенола, применяемых для профилактики и комплексного лечения заболеваний кожи у детей раннего возраста. Регулярное применение несмываемых косметических продуктов, в  т. ч. кремов и  лосьонов для тела, очень широко распространено среди детей в  возрасте 0–4  лет. Однако в  большинстве случаев рекомендации по  применению топических лекарственных средств и (или) косметических средств по уходу за детской кожей основаны не на научных доказательствах, а на здравом смысле, мнениях экспертов, рекламе, личных предпочтениях родителей, фармацевтов, дерматологов и (или) педиатров. Например, детские присыпки имеют недостаточные адсорбирующие свойства, а после впитывания влаги фактически превращаются в мочевые компрессы, усугубляющие повреждение эпидермиса. Крахмалсодержащие присыпки после набухания – превосходная среда для роста патогенной и условно-патогенной микрофлоры. Отмечено, что только правильный уход за кожей детей раннего возраста позволяет сохранить ее целостность и функциональное состояние. Особое внимание уделено препаратам на основе декспантенола в виде крема и мази, которые соответствуют всем критериям, предъявляемым к топическим средствам, эффективно защищают кожу от раздражителей, способствуют ее заживлению и восстановлению, увеличивают эластичность, упругость, оказывают противовоспалительное действие и могут применяться для профилактики и лечения заболеваний кожи детей раннего возраста, а также в качестве средств базисного ухода. Их эффективность неоднократно подтверждена в рамках многочисленных отечественных и зарубежных рандомизированных контролируемых исследований в популяциях новорожденных различного гестационного возраста, что явилось научным обоснованием для их широкого применения в реальной практике педиатров, дерматологов и аллергологов.

The article provides information about the features of the structure, development and differentiated approach to the appointment of dexapanthenol preparations used for the prevention and complex treatment of skin diseases in children of wounded age. Regular use of leave-on cosmetic products including body creams and lotions is very high among children aged 0–4 years. However, in most cases, recommendations for the use of topical baby skin care medicinal products and/or cosmetic products are based not on scientific evidence, but on common sense, expert opinions, advertising, personal preferences of parents, pharmacists, dermatologists and/or pediatricians. For example, adsorbing properties of baby powders are insufficient, and after absorbing moisture, they actually turn to “urine compresses” that aggravate the epidermis injury. After swelling, the starch-containing powders represent an excellent growth media for pathogenic and opportunistic microflora. It is noted that only proper skin care for young children allows you to preserve its integrity and functional state. Special attention is paid to the preparations of the Bepanten® series in the form of cream and ointment, which meet all the criteria for topical products, and can be used for the prevention and treatment of skin diseases in young children, effectively protecting the skin from irritants, promoting its healing and recovery, having an anti-inflammatory effect, increasing its elasticity, elasticity and are recommended for use as a means of basic care. Their effectiveness has been repeatedly confirmed in the numerous domestic and foreign randomized controlled studies in new-born populations at different gestational ages, which provided the scientific justification for their common use in the ‘real-life’ practice of pediatricians, dermatologists and allergists.

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The authors declare that there are no conflicts of interest present.