medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2022-16-13-11-16medsovet-7004Research ArticleЗАБОЛЕВАНИЯ КОЖИDERMAL DISEASESВопросы терапии поствоспалительной гиперпигментации постакнеIssues of therapy for post-acne post-inflammatory hyperpigmentationhttps://orcid.org/0000-0002-5044-5265КругловаЛ. С.KruglovaL. S.

д.м.н., профессор, проректор по учебной работе, заведующая кафедрой дерматовенерологии и косметологии,121359, Москва, ул. Маршала Тимошенко, д. 19, стр. 1а

Dr. Sci. (Med.), Professor, Pro-Vice-Chancellor for Academic Affairs, Head of Department of  Dermatovenereology and Cosmetology,

19, Bldg. 1а, Marshal Timoshenko St., Moscow, 150000

kruglovals@mail.ruhttps://orcid.org/0000-0003-3437-5233ГрязеваН. В.GryazevaN. V.

к.м.н., доцент кафедры дерматовенерологии и косметологии,

121359, Москва, ул. Маршала Тимошенко, д. 19, стр. 1a

Cand. Sci. (Med.), Associate Professor of Department of Dermatovenereology and Cosmetology,

19, Bldg. 1а, Marshal Timoshenko St., Moscow, 150000

tynrik@yandex.ruЦентральная государственная медицинская академияРоссияCentral State Medical Academy of Department for Presidential Affairs of the Russian FederationRussian Federation2022090820220131116Copyright © Круглова Л.С., Грязева Н.В., 20222022Круглова Л.С., Грязева Н.В.Kruglova L.S., Gryazeva N.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/7004Введение

Введение. Поствоспалительная гиперпигментация постакне наиболее часто формируется у  пациентов со  среднетяжелой и тяжелой степенью акне. Пигментация постакне может носить стойкий характер и сохраняться от месяцев до нескольких лет, что оказывает отрицательное влияние на качество жизни пациентов. Она встречается в любом возрасте с одинаковой частотой у мужчин и женщин.

Цель исследования

Цель исследования. Оценить влияние дерматокосметических средств – сыворотки с тройным действием (на основе тиамидола, салициловой кислоты и  ликохалкона А) и  флюида для проблемной кожи SPF30  на  состояние кожи у  пациентов со среднетяжелой и тяжелой поствоспалительной гиперпигментацией постакне.

Материал и  методы

Материал и  методы. Под наблюдением находилось 57  пациентов с  поствоспалительной гиперпигментацией постакне с локализацией на коже лица. Возраст пациентов составил 22,4 ± 2,7 года. У 32 пациентов диагностировалась легкая степень тяжести ПВГ постакне, у 25 – среднетяжелая степень ПВГ постакне. Все пациенты использовали дерматокосметические средства – сыворотку с тройным действием (на основе тиамидола, салициловой кислоты и ликохалкона А) и флюид для проблемной кожи SPF30. Оценка эффективности проводилась с  учетом данных мексаметрии, GSS, дерматологического индекса качества жизни. Для обработки цифрового материала применялись стандартные медицинские статистические методы: высчитывание среднеарифметического значения (Х), квадратичного отклонения (σ), критерий Стьюдента (t).

Результаты

Результаты. Через 12 нед. показатель мексаметрии снизился: 92,7 и 85,9% при легкой и среднетяжелой степени тяжести соответственно. Индекс ДИКЖ к концу лечения редуцировал на 84,9 и 83,8%.

Выводы

Выводы. Применение инновационных дерматокосметических средств на  основе салициловой кислоты и  ликохалкона А эффективно уменьшает пигментацию постакне. Все пациенты отметили хорошие органолептические свойства: комфортность нанесения на кожу и отличную переносимость препаратов. 

Introduction

Introduction. Post-acne post-inflammatory hyperpigmentation most often develops in patients with moderate to severe acne. Post-acne pigmentation can be persistent and last from months to several years, which has a negative impact on the patients’ quality of life. It occurs at any age with the same frequency in men and women.

Aim

Aim. To evaluate the effect of dermatocosmetic products – a triple effect serum (containing thiamidol, salicylic acid and lycochalcone A) and SPF30 fluid for problematic skin on the skin condition in patients with moderate and severe post-acne post-inflammatory hyperpigmentation.

Material and methods

Material and methods. A total of 57 patients with post-acne post-inflammatory hyperpigmentation localized on the facial skin were under observation. The age of the patients was 22.4 ± 2.7 years. 32 patients were diagnosed with mild post-acne PIH, 25 patients – with moderate post-acne PIH. All patients used dermocosmetic products such as the triple effect serum (containing thiamidol, salicylic acid and lycochalcone A) and SPF30 fluid for problematic skin. Efficacy was evaluated with due account for mexametry findings, GSS, dermatology life quality index. Digital data were processed using standard medical statistical methods: calculation of the arithmetic mean value (X), square deviation (σ), Student’s t-test (t).

Results

Results. After 12 weeks the mexometric index decreased: 92.7 and 85.9% in mild and moderate post-acne PIH, respectively. The DLQ index reduced by 84.9 and 83.8% by the end of the treatment,

Conclusions

Conclusions. The use of innovative dermocosmetic products containing salicylic acid and licochalcon A effectively reduces post-acne pigmentation. All patients noted good organoleptic properties: skin application comfort and excellent tolerability of the products.

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The authors declare that there are no conflicts of interest present.