medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2022-16-16-101-107medsovet-7096Research ArticleПРЕГРАВИДАРНАЯ ПОДГОТОВКА И БЕРЕМЕННОСТЬPREGRAVID PREPARATION AND PREGNANCYРоль микронутриентов в сохранении женского репродуктивного потенциала, сниженного на фоне инфекционных заболеванийThe role of micronutrients in maintaining women’s reproductive potential reduced due to infectious diseaseshttps://orcid.org/0000-0002-7150-2230СыркашеваА. Г.SyrkashevaA. G.

Анастасия Григорьевна Сыркашева, к. м. н., старший научный сотрудник

отделение вспомогательных технологий в лечении бесплодия имени проф. Б. В. Леонова

117997

ул. Академика Опарина, д. 4

Москва

Anastasiya G. Syrkasheva, Cand. Sci. (Med.), Senior Researcher

Professor B. V. Leonov Department of Assisted Reproductive Technology inInfertility Treatment

117997

4, Academician Oparin St.

Moscow

a_syrkasheva@oparina4.ruhttps://orcid.org/0000-0002-7775-3508ЛисицынаО. И.LisitsynaO. I.

Ольга Игоревна Лисицына, аспирант

отделение вспомогательных технологий в лечении бесплодия имени проф. Б. В. Леонова

117997

ул. Академика Опарина, д. 4

Москва

Olga I. Lisitsyna, Postgraduate Student

Professor B. V. Leonov Department of Assisted Reproductive Technology in Infertility Treatment

117997

4, Academician Oparin St.

Moscow

o_yazykova@inbox.ruНациональный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени академика В. И. КулаковаРоссияKulakov National Medical Research Center of Obstetrics, Gynecology and PerinatologyRussian Federation202209102022016101107Copyright © Сыркашева А.Г., Лисицына О.И., 20222022Сыркашева А.Г., Лисицына О.И.Syrkasheva A.G., Lisitsyna O.I.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/7096

   Иммунная система человека, находящаяся в тесной связи с другими органами и системами, в т. ч. с репродуктивной, необходима для защиты организма от инфекций, а также других внешних и внутренних факторов. Для нормальной функции иммунной системы необходим полноценный рацион с достаточным содержанием не только макро-, но и микронутриентов. В различных исследованиях показана связь между дефицитом различных витаминов и микроэлементов и снижением активности иммунной системы. Таким образом, иммунный ответ может быть нарушен при недостаточном питании и дефиците микроэлементов, что повышает восприимчивость организма к инфекционным факторам. В свою очередь, инфекционный процесс может привести к повышенной потребности в микроэлементах, которая удовлетворяется за счет экзогенных веществ, а при недостатке их потребления – за счет эндогенных запасов. Инфекции – один из основных факторов, ухудшающих репродуктивное здоровье человека. В структуре гинекологической патологии воспалительные заболевания органов малого таза (ВЗОМТ) занимают лидирующие позиции, а их распространенность не демонстрирует тенденции к снижению. В данном обзоре литературы рассмотрено влияние основных инфекций на репродуктивное здоровье женщины, представлены данные о роли микронутриентов в профилактике инфекционных заболеваний и реабилитации после них, а также в сохранении репродуктивных функций после перенесенных инфекций. Рассмотрено значение витаминов С, Е, витаминов группы В, цинка, L-аргинина для сохранения и восстановления фертильности у женщин, приведены результаты исследований, посвященных проблеме.

   The human immune system, which is in close connection with other organs and systems including the reproductive one, is required for the body’s defence against infections, as well as other external and internal factors. A balanced diet with a sufficient content of not only macro-, but also micronutrients is necessary for the normal function of the immune system. Various studies showed a relationship between the deficiency of various vitamins and trace elements and decreased activity of the immune system. Thus, the immune response can be impaired by malnutrition and trace element deficiency, which increases the body’s susceptibility to infectious factors. In its turn, the infectious process can lead to an increased demand for micronutrients, which is met by exogenous substances, and in case of not enough consumption of them – by endogenous reserves. Infections are one of the main factors deteriorating human reproductive health. Pelvic inflammatory diseases (PID) hold leading positions in the gynecological pathology pattern, and their prevalence does not show a downward trend. This literature review considers the impact of major infections on women’s reproductive health, presents data on the role of micronutrients in preventing infectious diseases and rehabilitating after them, as well as in preserving reproductive functions after infections. The importance of vitamin C, E, B vitamins, zinc, L-arginine for the preservation and restoration of women’s fertility is considered, and the results of studies on the issue are presented.

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The authors declare that there are no conflicts of interest present.