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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2022-16-17-13-19</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-7106</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АТЕРОСКЛЕРОЗ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ATHEROSCLEROSIS</subject></subj-group></article-categories><title-group><article-title>Прогнозирование сосудистых событий у лиц с атеросклеротическим поражением различных сосудистых бассейнов: результаты 3-летнего проспективного наблюдения</article-title><trans-title-group xml:lang="en"><trans-title>Prediction of vascular events in individuals with atherosclerotic lesions of various vascular basins: results of a 3-year prospective follow-up</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3390-2452</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кобзева</surname><given-names>Н. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kobzeva</surname><given-names>N. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент кафедры внутренних болезней №1, </p><p>344022, Ростов-на-Дону, Нахичеванский пер., д. 29</p></bio><bio xml:lang="en"><p>Cand. Sci. (Med.), Associate Professor of the Department of Internal Medicine No. 1,</p><p>29, Nakhichevan Lane, Rostov-on-Don, 344022</p></bio><email xlink:type="simple">kobzeva.nataliya1@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3607-5832</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терентьев</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Terentev</surname><given-names>V. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрой внутренних болезней №1,</p><p>344022, Ростов-на-Дону, Нахичеванский пер., д. 29</p></bio><bio xml:lang="en"><p>Dr. Sci. (Med.), Professor, Head of the Department of Internal Medicine No. 1,</p><p>29, Nakhichevan Lane, Rostov-on-Don, 344022</p></bio><email xlink:type="simple">vpterentev@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1304-6046</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Олейникова</surname><given-names>В. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Oleynikova</surname><given-names>V. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>студент,</p><p>344022, Ростов-на-Дону, Нахичеванский пер., д. 29</p></bio><bio xml:lang="en"><p>Student,</p><p>29, Nakhichevan Lane, Rostov-on-Don, 344022</p></bio><email xlink:type="simple">victoria-ol@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ростовский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>12</day><month>10</month><year>2022</year></pub-date><volume>0</volume><issue>17</issue><fpage>13</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кобзева Н.Д., Терентьев В.П., Олейникова В.Д., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Кобзева Н.Д., Терентьев В.П., Олейникова В.Д.</copyright-holder><copyright-holder xml:lang="en">Kobzeva N.D., Terentev V.P., Oleynikova V.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/7106">https://www.med-sovet.pro/jour/article/view/7106</self-uri><abstract><sec><title>Введение</title><p>Введение. Сегодня сердечно-сосудистые заболевания занимают лидирующие позиции в структуре смертности в России и во всем мире. Каждый год более 17 млн человек умирают от кардиальной патологии. По данным ВОЗ, в перспективе ожидается рост заболеваемости и смертности, что объясняется в первую очередь увеличением количества больных с сахарным диабетом и ожирением.</p></sec><sec><title>Цель</title><p>Цель. Разработать оптимальные подходы к прогнозированию сердечно-сосудистых событий и неблагоприятных исходов у больных с периферическим атеросклерозом в ходе 3-летнего проспективного наблюдения.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование включено 519 пациентов с атеросклеротическим поражением различных сосудистых бассейнов, из них 360 (69,4%) мужчин, 159 (30,6%) женщин. Средний возраст обследованных больных составил 60,0 ± 8,7 года.</p></sec><sec><title>Результаты</title><p>Результаты. В ходе проведенного анализа было отмечено, что такой фактор, как процент стенозирования ствола левой коронарной артерии (р = 0,013), оказывал влияние на риск развития нефатальных случаев сердечной недостаточности у пациентов с периферическим атеросклерозом. В отношении конечной точки – фатальные случаи сердечной недостаточности – свою статистическую значимость продемонстрировали следующие факторы: возраст дебюта артериальной гипертензии, лет  (р = 0,020); наличие в анамнезе хронической сердечной недостаточности  (р = 0,020); размер левого предсердия, мм  (р  =  0,025); степень стенозирования задней боковой ветви, %  (р = 0,038); наличие атеросклеротического поражения в области задней межжелудочковой ветви (р = 0,002); количество пораженных сосудистых бассейнов (р = 0,044).</p></sec><sec><title>Выводы</title><p>Выводы. С помощью уравнений логистической регрессии разработаны оригинальные математические инструменты с целью оценки риска развития как фатальной, так и нефатальной сердечной недостаточности у больных с периферическим атеросклерозом. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Today, cardiovascular diseases occupy a leading position in the structure of mortality, both in Russia and throughout the  world. Every year more than 17  million people die from cardiac pathology, according to the World Health Organization, an increase in morbidity and mortality is expected in the future, which is explained, first of all, by an increase in the number of patients with diabetes and obesity.</p></sec><sec><title>Aim</title><p>Aim. Development of optimal approaches to predicting cardiovascular events and unfavorable outcomes in patients with peripheral atherosclerosis during a 3-year prospective follow-up.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study included 519  patients with atherosclerotic lesions of  various vascular regions, of  which 360 (69.4%) were men, 159 (30.6%) were women. The average age of the examined patients was 60.0 ± 8.7 years.</p></sec><sec><title>Results</title><p>Results. In the course of the analysis, it was noted that a factor such as the percentage of table stenosis of the left coronary artery (p = 0.013) influenced the risk of developing non-fatal cases of heart failure in patients with peripheral atherosclerosis. With regard to the end point – fatal cases of heart failure, the following factors demonstrated their statistical significance: age of onset of arterial hypertension, years (p = 0.020); history of chronic heart failure (p = 0.020); left atrial size, mm (p = 0.025); degree of stenosis of the posterior lateral branch, % (p = 0.038); presence of atherosclerotic lesions in the region of the posterior interventricular branch (p = 0.002); number of affected vascular beds (p = 0.044).</p></sec><sec><title>Conclusions</title><p>Conclusions. Using logistic regression equations, original mathematical tools have been developed to assess the risk of developing both fatal and non-fatal heart failure in patients with peripheral atherosclerosis. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>инсульт</kwd><kwd>атеросклероз коронарных артерий</kwd><kwd>артерии нижних конечностей</kwd><kwd>сердечная недостаточность</kwd><kwd>фатальные исходы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>stroke</kwd><kwd>atherosclerosis of the coronary arteries</kwd><kwd>arteries of the lower extremities</kwd><kwd>heart failure</kwd><kwd>fatal outcomes</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бойцов С.А., Шальнова С.А., Деев А.Д. Эпидемиологическая ситуация как фактор, определяющий стратегию действий по снижению смертности в Российской Федерации. 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