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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2016-4-28-35</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-73</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КАРДИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>Влияние блокаторов рецепторов к ангиотензину II и антагонистов кальция на когнитивные функции</article-title><trans-title-group xml:lang="en"><trans-title>Effect of angiotensin II receptor blockers and calcium antagonists on cognition</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Остроумова</surname><given-names>О. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Ostroumova</surname><given-names>O. D.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Первичко</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Pervichko</surname><given-names>E. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галеева</surname><given-names>Н. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Galeeva</surname><given-names>N. Y.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский государственный медико-стоматологический университет им. А.И. Евдокимова; Первый Московский государственный медицинский университет им. И.М. Сеченова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow State University of Medicine and Dentistry named after A.I. Yevdokimov; First Moscow State Medical University named after I.M. Sechenov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Московский государственный университет им. М.В. Ломоносова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow State University named after M.V. Lomonosov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Городская клиническая больница №70</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City clinical hospital No.70</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2016</year></pub-date><volume>0</volume><issue>4</issue><fpage>28</fpage><lpage>35</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Остроумова О.Д., Первичко Е.И., Галеева Н.Ю., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Остроумова О.Д., Первичко Е.И., Галеева Н.Ю.</copyright-holder><copyright-holder xml:lang="en">Ostroumova O.D., Pervichko E.I., Galeeva N.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/73">https://www.med-sovet.pro/jour/article/view/73</self-uri><abstract><p>В статье приведены определение, классификация и патогенетические механизмы нарушения когнитивных функций при артериальной гипертонии. Обсуждаются возможности антигипертензивных препаратов разных классов в коррекции когнитивных нарушений и профилактике деменции. Рассмотрены потенциальные механизмы коррекции когнитивных функций на фоне лечения блока-торами рецепторов к ангиотензину II и антагонистами кальция.</p></abstract><trans-abstract xml:lang="en"><p>The article offers a definition, classification and describes the pathogenetic mechanisms of cognitive impairment in patients with arterial hypertension. The potential of different classes of antihypertensive drugs in the management of cognitive impairment and dementia prevention is discussed. The possible mechanisms of the improvement of cognitive functions during treatment with angiotensin II receptor blockers and calcium antagonists are considered.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертония</kwd><kwd>когнитивные функции</kwd><kwd>деменция</kwd><kwd>антигипертензивная терапия</kwd><kwd>антагонисты рецепторов к ангиотензину II</kwd><kwd>лозартан</kwd><kwd>антагонисты кальция</kwd><kwd>амлодипин</kwd><kwd>hypertension</kwd><kwd>cognitive functions</kwd><kwd>dementia</kwd><kwd>antihypertensive therapy</kwd><kwd>angiotensin II receptor blockers</kwd><kwd>losartan</kwd><kwd>calcium antagonists</kwd><kwd>amlodipine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Захаров В.В., Локшина А.Б. Когнитивные нарушения в общеклинической практике. М., 2009, 8 с.</mixed-citation><mixed-citation xml:lang="en">Захаров В.В., Локшина А.Б. 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