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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/ms2023-081</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-7467</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРЕ- И ПОСТМЕНОПАУЗА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PRE- AND POSTMENOPAUSE</subject></subj-group></article-categories><title-group><article-title>Психоэмоциональное состояние женщин в период перименопаузального перехода</article-title><trans-title-group xml:lang="en"><trans-title>Psycho-emotional state of women during the perimenopausal transition</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9491-9303</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маркова</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Markova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Маркова Элеонора Александровна, к.м.н., ассистент кафедры акушерства и гинекологии,</p><p>117997, Москва, ул. Островитянова, д. 1</p></bio><bio xml:lang="en"><p>Eleonora A. Markova, Cand. Sci. (Med.), Teaching Assistant of Department of Obstetrics and Gynaecology,</p><p>1, Ostrovityanov St., Moscow, 117997</p></bio><email xlink:type="simple">markova.eleonora@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7591-6281</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хашукоева</surname><given-names>А. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Khashukoeva</surname><given-names>A. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хашукоева Асият Зульчифовна, д.м.н., профессор кафедры акушерства и  гинекологии,</p><p>117997, Москва, ул. Островитянова, д. 1</p></bio><bio xml:lang="en"><p>Asiyat Z. Khashukoeva, Dr. Sci. (Med.), Professor of Department of Obstetrics and Gynaecology,</p><p>1, Ostrovityanov St., Moscow, 117997</p></bio><email xlink:type="simple">azk05@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет имени Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>22</day><month>04</month><year>2023</year></pub-date><volume>0</volume><issue>5</issue><fpage>168</fpage><lpage>175</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Маркова Э.А., Хашукоева А.З., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Маркова Э.А., Хашукоева А.З.</copyright-holder><copyright-holder xml:lang="en">Markova E.A., Khashukoeva A.Z.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/7467">https://www.med-sovet.pro/jour/article/view/7467</self-uri><abstract><p>Здоровье женщины в период перименопаузального перехода не теряет своей актуальности ввиду того риска, которому подвергается данная категория женщин. У пациенток зрелого возраста часто возникают жалобы, ассоциированные с климактерическим синдромом. Увеличение продолжительности жизни женщины, активный образ жизни, который она хочет, но не всегда может поддерживать по причине наличия ряда неблагоприятных факторов, таких как экология, стрессовые факторы, наличие хронических заболеваний, имеющих тенденцию к  частым обострениям,  – все это усугубляет общее состояние женщины и в первую очередь негативно сказывается на ее психоэмоциональном здоровье. Климактерический синдром, который может дебютировать в  периоде перименопаузального перехода, еще больше осложняет состояние женщины. Работа врача-гинеколога заключается в ведении таких пациенток и помощи им. Казалось бы, в клинических рекомендациях и  протоколах четко прописаны алгоритмы ведения и  терапии таких пациенток, сказано о  назначении менопаузальной гормональной терапии, которая является патогенетической и обоснованной при развитии климактерического синдрома и  жалобах, ассоциированных с  ним. Но  назначение данной терапии связано с  совокупностью рисков и  побочных эффектов. Негормональная терапия  – хорошая альтернатива при лечении климактерических расстройств, учитывая, что гормональные препараты противопоказаны ряду женщин. В данной статье представлен обзор литературных данных по результатам назначения биологически активной добавки Менсе® у женщин с психоэмоциональным напряжением в  период менопаузы. Комплекс Менсе® содержит внушительное количество компонентов: β-аланин, 5-гидрокситриптофан, фитоэстрогены – изофлавоны сои, витамины группы В, фолиевая кислота, витамины Е и С, благоприятно воздействующих на организм женщины и повышающих качество ее жизни в период перименопаузы. Данный комплекс может быть рекомендован пациенткам с климактерическим синдромом как эффективное терапевтическое средство на период подбора менопаузальной гормональной терапии или при наличии противопоказаний к  ней. Менсе®  – эффективная помощь в повышении качества жизни женщин в перименопаузе на фоне психоэмоционального напряжения. </p></abstract><trans-abstract xml:lang="en"><p>A woman’s health during the perimenopausal transition is not irrelevant because of the risk zone in which this category of women falls. Mature patients often have complaints associated with the menopausal syndrome. The increase in life expectancy of women, their active lifestyle that they want to maintain, which is not always possible due to the presence of a number of adverse factors such as the environment, stress factors, the presence of chronic diseases that tend to frequent exacerbations, all this aggravates the overall condition of women and primarily has a negative impact on their psycho-emotional health. The menopausal syndrome, which can debut during the perimenopausal transition, further complicates the woman’s condition. The job of a specialist gynaecologist is to help and manage these patients. It would seem that there is no question: the clinical guidelines and protocols are clearly prescribed algorithms for the management and therapy of such patients, where it is stated in black and white about the prescription of menopausal hormone therapy, which is pathogenetic and justified in the development of the menopausal syndrome and the complaints associated with it. But the prescription of this therapy is associated with a set of risks and side effects. Non-hormonal therapy is a good alternative in the treatment of menopausal disorders, given that hormonal treatment is contraindicated in a number of women. This article presents a cross-section of the literature data on the results of prescribing a dietary supplement MENSE® (Aquion JSC, Russia) in women with psycho-emotional tension during menopause. MENSE® complex contains an impressive range of components (β-alanine, 5-hydroxytryptophan, phytoestrogens – soy isoflavones, B vitamins, folic acid, vitamins E and C) favorably affecting the female body and improves the quality of her life during perimenopause. This complex can be recommended for patients with menopausal syndrome as an effective therapeutic agent for the period of selection of menopausal hormonal therapy or the presence of contraindications to it. MENSE® is an effective complex for improving the quality of life of perimenopausal women against the background of psycho-emotional conditions. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>климактерический синдром</kwd><kwd>перименопауза</kwd><kwd>фитоэстрогены</kwd><kwd>негормональная терапия</kwd><kwd>биологически активная добавка</kwd></kwd-group><kwd-group xml:lang="en"><kwd>menopausal syndrome</kwd><kwd>perimenopause</kwd><kwd>phytoestrogens</kwd><kwd>non-hormonal therapy</kwd><kwd>dietary supplement</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Harlow S.D., Gass M., Hall J.E., Lobo R., Maki P., Rebar R.W. et al. Executive summary of the Stages of Reproductive Aging Workshop + 10: addressing the unfinished agenda of staging reproductive aging. 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