medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/2079-701X-2014-16-6-11medsovet-754Research ArticleХроническая обструктивная болезнь легкихChronic obstructive pulmonary diseaseГликопиррония бромид - новый длительно действующий антихолинергический препарат для терапии ХОБЛGlycopyrronium bromide is a new long-acting anticholinergic drug for the treatment of COPDАвдеевС. Н.AvdeevS. N.noemail@neicon.ruЧикинаС. Ю.ChikinaS. Y.noemail@neicon.ruНИИ пульмонологии ФМБА РоссииРоссияScientific Research Institute of Pulmonology, Federal Medical and Biological Agency of RussiaRussian Federation201430122014016611Copyright © Авдеев С.Н., Чикина С.Ю., 20142014Авдеев С.Н., Чикина С.Ю.Avdeev S.N., Chikina S.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/754

Гликопирроний - новый антихолинергический препарат с мощным, быстро наступающим бронходилатационным эффектом, предназначенный для лечения хронической обструктивной болезни легких. Гликопирроний выпускается в виде пудры в ингаляционном устройстве Бризхалер. В данном обзоре рассказывается о клинических исследованиях III фазы, в которых продемонстрировано эффективное влияние гликопиррония на легочную функцию, выраженность симптомов заболевания, переносимость больными физической нагрузки, частоту тяжелых и среднетяжелых обострений ХОБЛ и качество жизни больных. Показана хорошая переносимость препарата, включая высокую кардиологическую безопасность при длительном применении.

Glycopyrronium is a new powerful quick-acting anticholinergic bronchodilator for the treatment of chronic obstructive pulmonary disease. Glycopyrronium is powder in Breezhaler® inhalation device. The review tells about phase III clinical trials demonstrating the positive effect of glycopyrronium on lung function, symptoms of the disease, exercise tolerance, frequency of severe and moderate COPD exacerbations and quality of life of patients. The drug showed good tolerability and high cardiac safety in a long-term period.

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The authors declare that there are no conflicts of interest present.