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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/2079-701X-2014-17-23-27</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-769</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Новости</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>News. Findings and events</subject></subj-group></article-categories><title-group><article-title>Внебольничная пневмония на фоне хронической сердечной недостаточности: особенности диагностики и лечения</article-title><trans-title-group xml:lang="en"><trans-title>Community-acquired pneumonia against a background of chronic heart failure: diagnosis and treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бобылев</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bobylev</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рачина</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rachina</surname><given-names>S. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козлов</surname><given-names>Р. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlov</surname><given-names>R. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дехнич</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Dekhnich</surname><given-names>N. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Смоленская государственная медицинская академия Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Smolensk State Medical Academy, Russia's Ministry of Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Смоленская государственная медицинская академия Минздрава России; НИИ антимикробной химиотерапии, Смоленск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Smolensk State Medical Academy, Russia's Ministry of Health; Research Institute of Antimicrobial Chemotherapy, Smolensk</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>НИИ антимикробной химиотерапии, Смоленск ; НИИ антимикробной химиотерапии, Смоленск</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Antimicrobial Chemotherapy, Smolensk</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2014</year></pub-date><volume>0</volume><issue>17</issue><fpage>23</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бобылев А.А., Рачина С.А., Козлов Р.С., Дехнич Н.Н., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Бобылев А.А., Рачина С.А., Козлов Р.С., Дехнич Н.Н.</copyright-holder><copyright-holder xml:lang="en">Bobylev A.A., Rachina S.A., Kozlov R.S., Dekhnich N.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/769">https://www.med-sovet.pro/jour/article/view/769</self-uri><abstract><p>Внебольничная пневмония - одно из наиболее часто встречающихся инфекционных заболеваний в развитых странах. Хроническая сердечная недостаточность является независимым фактором риска неблагоприятного течения и прогноза при внебольничной пневмонии. Объективные трудности клинической, рентгенологической, лабораторной и микробиологической диагностики внебольничной пневмонии у пожилых пациентов с хронической сердечной недостаточностью обусловливают необходимость более широкого использования в рутинной практике определения сывороточных биомаркеров воспаления. Системная антибактериальная терапия у данной категории больных проводится в соответствии с общепринятыми рекомендациями, но должна учитывать некоторые особенности этиологии, влияние сопутствующей функциональной недостаточности систем органов и дополнительной медикаментозной терапии на фармакокинетику антимикробных препаратов, а также возможное потенцирование нежелательных реакций при одновременном назначении некоторых лекарственных средств.</p></abstract><trans-abstract xml:lang="en"><p>Community-acquired pneumonia is one of the most common infectious diseases in developed countries. Chronic heart failure is an independent risk factor for unfavorable course and prognosis of community-acquired pneumonia. Objective challenges of clinical, radiological, laboratory and microbiological diagnosis of community-acquired pneumonia in elderly patients with chronic heart failure dictate the need for a greater number of physicians to routinely examine for serum biomarkers of inflammation. Systemic antibiotic therapy for the category of patients is carried out in accordance with the standard guidelines and should be based on certain peculiarities of the etiology, impact of concomitant functional impairment of the organ systems and additional medication therapy on the pharmacokinetics of antimicrobial agents, and take into account the risk of potentiation of adverse reactions as a result of administration of drugs.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>внебольничная пневмония</kwd><kwd>инфекции нижних дыхательных путей</kwd><kwd>хроническая сердечная недостаточность</kwd><kwd>диагностика</kwd><kwd>лечение</kwd><kwd>антибактериальная терапия</kwd><kwd>фторхинолоны</kwd><kwd>левофлоксацин</kwd><kwd>моксифлоксацин</kwd><kwd>community-acquired pneumonia</kwd><kwd>lower respiratory tract infections</kwd><kwd>chronic heart failure</kwd><kwd>diagnosis</kwd><kwd>treatment</kwd><kwd>antibiotic therapy</kwd><kwd>fluoroquinolones</kwd><kwd>levofloxacin</kwd><kwd>moxifloxacin</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Trotter CL, Stuart JM, George R et al. 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