medsovetМедицинский СоветMeditsinskiy sovet = Medical Council2079-701X2658-5790REMEDIUM GROUP Ltd.10.21518/ms2023-342medsovet-7793Research ArticleПРЕ- И ПОСТМЕНОПАУЗАPRE- AND POSTMENOPAUSEМенопаузальный переход. Можно ли отсрочить назначение менопаузальной гормональной терапии?Menopausal transition. Is it possible to delay the prescription of menopausal hormone therapy?https://orcid.org/0000-0001-7591-6281ХашукоеваА. З.KhashukoevaA. Z.

Хашукоева Асият Зульчифовна – доктор медицинских наук, профессор, профессор кафедры акушерства и гинекологии лечебного факультета, РНИМУ им. Н.И. Пирогова; профессор кафедры акушерства и гинекологии, РГНКЦ.

117997, Москва, ул. Островитянова, д. 1; 129226, Москва, ул. 1-я Леонова, д. 16

Asiyat Z. Khashukoeva - Dr. Sci. (Med.), Professor, Professor of the Department of Obstetrics and Gynecology, Faculty of Medicine, Pirogov Russian National Research Medical University; Professor of the Department of Obstetrics and Gynecology, Russian Clinical and Research Center of Gerontology.

1, Ostrovityanov St., Moscow, 117997; 16, 1st Leonov St, Moscow, 129226

azk05@mail.ruhttps://orcid.org/0000-0002-9491-9303МарковаЭ. А.MarkovaE. A.

Маркова Элеонора Александровна – кандидат медицинских наук, ассистент кафедры акушерства и гинекологии лечебного факультета.

117997, Москва, ул. Островитянова, д. 1

Eleonora A. Markova - Cand. Sci. (Med.), Assistant at the Department of Obstetrics and Gynecology, Faculty of Medicine, Pirogov Russian National Research Medical University.

1, Ostrovityanov St., Moscow, 117997

markova.eleonora@mail.ruБурденкоМ. В.BurdenkoM. V.

Бурденко Марина Владимировна - кандидат медицинских наук, доцент кафедры акушерства и гинекологии лечебного факультета.

117997, Москва, ул. Островитянова, д. 1

Marina V. Burdenko - Cand. Sci. (Med.), Associate Professor of the Department of Obstetrics and Gynecology, Faculty of Medicine, Pirogov Russian National Research Medical University.

1, Ostrovityanov St., Moscow, 117997

bmv-0306@rambler.ruhttps://orcid.org/0000-0002-0925-3755НосоваЛ. A.NosovaL. A.

Носова Лилия Андреевна - аспирант кафедры акушерства и гинекологии лечебного факультета.

117997, Москва, ул. Островитянова, д. 1

Lilia A. Nosova - Postgraduate Student of the Department of Obstetrics and Gynecology, Faculty of Medicine, Pirogov Russian National Research Medical University.

1, Ostrovityanov St., Moscow, 117997

karelina_lilia0@mail.ruСоловьеваА. М.SolovyovaA. M.

Соловьева Анна Михайловна - студент лечебного факультета.

117997, Москва, ул. Островитянова, д. 1

Anna M. Solovyova - Student of the Faculty of Medicine, Pirogov Russian National Research Medical University.

1, Ostrovityanov St., Moscow, 117997

annasol02@yandex.ruhttps://orcid.org/0009-0007-1229-3671ЛукьяноваЕ. А.LukyanovaE. A.

Лукьянова Екатерина Анатольевна - студент лечебного факультета.

117997, Москва, ул. Островитянова, д. 1

Ekaterina A. Lukyanova - Student of the Faculty of Medicine, Pirogov Russian National Research Medical University.

1, Ostrovityanov St., Moscow, 117997

yekaterina.lukyanova.99@bk.ruРоссийский национальный исследовательский медицинский университет имени Н.И. Пирогова; Российский геронтологический научно-клинический центрРоссияPirogov Russian National Research Medical University; Russian Clinical and Research Center of GerontologyRussian FederationРоссийский национальный исследовательский медицинский университет имени Н.И. ПироговаРоссияPirogov Russian National Research Medical UniversityRussian Federation202321102023015126133Copyright © Хашукоева А.З., Маркова Э.А., Бурденко М.В., Носова Л.A., Соловьева А.М., Лукьянова Е.А., 20232023Хашукоева А.З., Маркова Э.А., Бурденко М.В., Носова Л.A., Соловьева А.М., Лукьянова Е.А.Khashukoeva A.Z., Markova E.A., Burdenko M.V., Nosova L.A., Solovyova A.M., Lukyanova E.A.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.med-sovet.pro/jour/article/view/7793

После завершения репродуктивного периода треть своей жизни женщины проводят в менопаузе. В этот период они испытывают целый ряд предсказуемых симптомов и состояний, связанных с изменением уровня половых гормонов и старением организма. Менопаузальный переход предшествует менопаузе на несколько лет и обычно характеризуется нерегулярностью менструального цикла, приливами жара и ночной потливостью. После наступления менопаузы преобладают генитоуринарные симптомы, включая атрофию и сухость вульвовагинальной области, и жалобы, ассоциированные с нарушениями мочеиспускания: повышение частоты мочеиспусканий, ургентность и ноктурия. Менопаузальная гормональная терапия эффективна для устранения вазомоторных и мочеполовых симптомов, но она связана с развитием рисков сердечно-сосудистых заболеваний, когнитивных нарушений, депрессии и рядом  побочных эффектов. Альтернативой в терапии симптомов климактерия может стать назначение биологически активной добавки Хепиклим®. Комплексный состав препарата эффективно компенсирует недостаток собственных эстрогенов в женском организме. Препарат Хепиклим® содержит фитоэстрогены (изофлавоны сои, флавоноиды) и вспомогательные компоненты (магний и витамины группы В, витамин С, экстракт мелиссы лекарственной), которые с высокой эффективностью воздействуют на организм женщины в период менопаузального перехода, облегчая симптомы климактерия и повышая качество ее жизни. В статье представлен срез литературных данных по использованию фитоэстрогенов и биологически активной добавки Хепиклим® в период перименопаузального перехода с целью отсрочить назначение менопаузальной гормональной терапии.

After the end of the reproductive period, women spend a third of their lives in menopause. During this period, they experience a range of predictable symptoms and conditions associated with changing levels of sex hormones and aging of the body. The menopausal transition precedes menopause by several years and is usually characterized by irregular menstrual cycles, hot flashes and night sweats. After menopause, genitourinary symptoms predominate, including vulvovaginal atrophy and dryness and complaints associated with urinary disturbances: increased urinary frequency, urgency, and nocturia. Menopausal hormone therapy is effective for vasomotor and genitourinary symptoms, but it is associated with the development of cardiovascular risks, cognitive impairment, depression, and a number of side effects. An alternative in the therapy of menopausal symptoms can be the prescription of biologically active supplement Happyclim®. The complex composition of the drug effectively fills the lack of its own estrogen in the female body. The preparation Happyclim® contains phytoestrogens (soy isoflavones, flavonoids) and auxiliary components (magnesium and B vitamins, vitamin C, extract of medicinal melissa), which with high efficiency affect the woman’s body during menopausal transition, alleviating the symptoms of menopause and improving the quality of life. This article presents a cross-section of the literature on the use of phytoestrogens and the dietary supplement Happyclim® during the perimenopausal transition to delay the administration of menopausal hormone therapy.

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The authors declare that there are no conflicts of interest present.