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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medsovet</journal-id><journal-title-group><journal-title xml:lang="ru">Медицинский Совет</journal-title><trans-title-group xml:lang="en"><trans-title>Meditsinskiy sovet = Medical Council</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2079-701X</issn><issn pub-type="epub">2658-5790</issn><publisher><publisher-name>REMEDIUM GROUP Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21518/ms2023-392</article-id><article-id custom-type="elpub" pub-id-type="custom">medsovet-7867</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОМОРБИДНЫЙ ПАЦИЕНТ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COMORBID PATIENT</subject></subj-group></article-categories><title-group><article-title>Характеристика нутритивного статуса пациентов с хронической болезнью почек</article-title><trans-title-group xml:lang="en"><trans-title>Characteristics of nutritional status in patients with chronic kidney disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8247-061X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тишкина</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tishkina</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тишкина Светлана Владимировна - врач-нефролог.</p><p>119049, Москва, Ленинский проспект, д. 8</p></bio><bio xml:lang="en"><p>Svetlana V. Tishkina - Nephrologist, City Clinical  Hospital No. 1  named after N.I. Pirogov.</p><p>8, Leninsky Ave., Moscow, 119049</p></bio><email xlink:type="simple">svet0810@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6938-9665</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шеменкова</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shemenkova</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шеменкова Виктория Сергеевна - кандидат медицинских наук, ассистент кафедры пропедевтики внутренних болезней  лечебного факультета, РНИМУ им. Н.И. Пирогова; ведущий врач-терапевт,  кардиолог, врач функциональной  диагностики, Клиника персонализированной терапии  MedEx.</p><p>117997, Москва, ул. Островитянова, д. 1; 121170, Москва, Кутузовский проспект, д. 32, к. 1</p></bio><bio xml:lang="en"><p>Victoria S. Shemenkova - Cand. Sci. (Med.), Assistant  of the  Department of Propaedeutics of Internal  Diseases, Faculty of Medicine, Pirogov Russian National Research Medical University; Leading General Practitioner, Cardiologist, Doctor of Functional  Diagnostics, MedEx Personalized Therapy Clinic.</p><p>1, Ostrovityanov St., Moscow, 117997; 32, Bldg. 1, Kutuzovsky Ave., Moscow, 121170</p></bio><email xlink:type="simple">vshemenkova@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4918-3795</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Константинова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Konstantinova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Константинова Екатерина Владимировна - доктор медицинских наук, доцент кафедры факультетской терапии имени акад. А.И. Нестерова, профессор  кафедры интервенционной  кардиологии и кардиореабилитации, РНИМУ им. Н.И. Пирогова; врач-кардиолог, ГКБ №1 им. Н.И. Пирогова.</p><p>117997, Москва, ул. Островитянова, д. 1; 119049, Москва, Ленинский проспект, д. 8</p></bio><bio xml:lang="en"><p>Ekaterina V. Konstantinova - Dr. Sci. (Med.), Associate Professor of the Department of Faculty Therapy named after Acad.  A.I. Nesterov, Professor of the Department of Interventional Cardiology and Cardiac Rehabilitation, Pirogov Russian National Research Medical University; Cardiologist, City Clinical Hospital No. 1 named after N.I. Pirogov.</p><p>1, Ostrovityanov St., Moscow, 117997; 8, Leninsky Ave., Moscow, 119049</p></bio><email xlink:type="simple">katekons@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Городская клиническая больница №1 им. Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital No. 1 named after N.I. Pirogov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российский национальный исследовательский  медицинский университет имени Н.И. Пирогова; Клиника персонализированной терапии MedEx</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National  Research Medical University; MedEx Personalized Therapy Clinic</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Городская клиническая больница №1 им. Н.И. Пирогова; Российский национальный исследовательский  медицинский университет имени Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital No. 1 named  after N.I. Pirogov; Pirogov Russian National  Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>04</day><month>11</month><year>2023</year></pub-date><volume>0</volume><issue>18</issue><fpage>166</fpage><lpage>174</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тишкина С.В., Шеменкова В.С., Константинова Е.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Тишкина С.В., Шеменкова В.С., Константинова Е.В.</copyright-holder><copyright-holder xml:lang="en">Tishkina S.V., Shemenkova V.S., Konstantinova E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.med-sovet.pro/jour/article/view/7867">https://www.med-sovet.pro/jour/article/view/7867</self-uri><abstract><p>Хроническая болезнь почек –это персистирующее в течение 3 мес. и более поражение почек вследствие действия различных этиологических факторов, анатомической основой которого является процесс замещения  нормальных анатомических структур фиброзом, приводящим к дисфункции. Данная нозология является достаточно распространенной в современном  мире, может прогрессировать  и приводить к инвалидизации  пациентов, снижению качества их жизни. Высоким остается и показатель летальности при данном заболевании. Около 3/4 пациентов с данной патологией имеют терминальную стадию процесса, для которой характерно развитие белково-энергетической недостаточности за счет уремии, мальнутриции, ацидоза  и персистирующего воспалительного процесса, значимо ухудшающих прогноз. В настоящее время в имеющейся литературе представлено небольшое количество работ, посвященных данной проблеме, поэтому важной частью ведения пациентов с хронической болезнью почек (в особенности  находящихся на гемодиализе)  является оценка и коррекция  нутритивного статуса. В статье освещены  аспекты  развития  белково-энергетической недостаточности, возможные  методы  ее  диагностики  и коррекции. Частыми осложнениями хронической болезни почек также являются электролитные нарушения, в особенности гиперкалиемия и гиперфосфатемия. Коррекция этих состояний, в свою очередь, может приводить к развитию недостаточности витаминов и других микроэлементов. Согласно представленным в литературе исследованиям, состояние нутритивного статуса – это один из главных факторов, определяющих  выживаемость  и степень реабилитации  пациентов, находящихся  на заместительной почечной терапии, а также эффективность диализного  лечения. Таким образом, знание  врачом-клиницистом  особенностей нутритивного статуса у данной группы пациентов позволяет улучшить прогноз и качество их жизни.</p></abstract><trans-abstract xml:lang="en"><p>Chronic kidney disease  is kidney damage  that persists  for three  months  or more due to the action of various etiological  factors, the anatomical basis of which is the process  of replacement of normal anatomical structures with fibrosis, leading  to its dysfunction. This nosology is quite common in the modern world; it can progress  and lead to disability of patients and a decrease in their  quality of life. The mortality  rate  for this disease  also remains  high. About 3/4  of patients with this pathology  have a terminal  stage  of the process, which is characterized by the development of protein-energy deficiency (due to uremia, malnutrition, acidosis and persistent inflammatory  process), which significantly worsens  the prognosis. Currently, the available  literature  contains  a small number  of works devoted  to this problem, therefore an important part of the  management of patients with chronic kidney disease  (especially  those  on hemodialysis)  is the  assessment and correction  of nutritional status. In this article, the authors  highlight  aspects  of the development of protein-energy malnutrition, its possible  methods of diagnosis and correction. Electrolyte disturbances, especially hyperkalemia  and hyperphosphatemia, are also common complications of chronic kidney disease.  Correction  of these  conditions,  in turn, can  lead  to the  development of deficiency  of vitamins  and  other microelements. According to studies presented in the literature, nutritional status  is one of the main factors determining the survival and degree  of rehabilitation of patients on renal replacement therapy, as well as the effectiveness of dialysis treatment. Thus, a clinician’s knowledge  of the nutritional status  of this group of patients can improve their prognosis  and quality of life.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гемодиализ</kwd><kwd>белково-энергетическая недостаточность</kwd><kwd>гипопротеинемия</kwd><kwd>оценка нутритивного статуса</kwd><kwd>коррекция нутритивного статуса</kwd><kwd>мальнутриция</kwd><kwd>гиперкалиемия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hemodialysis</kwd><kwd>protein-energy deficiency</kwd><kwd>hyperproteinemia</kwd><kwd>nutritional status  assessment</kwd><kwd>nutritional status correction</kwd><kwd>malnutrition</kwd><kwd>hyperkaliemia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">GBD Chronic Kidney Disease Collaboration. Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. 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